2020
Factors associated with hospital admission and critical illness among 5279 people with coronavirus disease 2019 in New York City: prospective cohort study
Petrilli CM, Jones SA, Yang J, Rajagopalan H, O'Donnell L, Chernyak Y, Tobin KA, Cerfolio RJ, Francois F, Horwitz LI. Factors associated with hospital admission and critical illness among 5279 people with coronavirus disease 2019 in New York City: prospective cohort study. The BMJ 2020, 369: m1966. PMID: 32444366, PMCID: PMC7243801, DOI: 10.1136/bmj.m1966.Peer-Reviewed Original ResearchConceptsBody mass indexProspective cohort studyCritical illnessCoronavirus disease 2019Hospital admissionCohort studyHeart failureMale sexDisease 2019Hospice careAcute respiratory syndrome coronavirus 2 infectionSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infectionSyndrome coronavirus 2 infectionC-reactive protein levelsSingle academic medical centerAdmission oxygen saturationCoronavirus 2 infectionReactive protein levelsChronic kidney diseaseD-dimer levelsMarkers of inflammationAge 75 yearsSeverity of illnessStrong riskMultivariable logistic regression
2019
Creating a Learning Health System through Rapid-Cycle, Randomized Testing
Horwitz LI, Kuznetsova M, Jones SA. Creating a Learning Health System through Rapid-Cycle, Randomized Testing. New England Journal Of Medicine 2019, 381: 1175-1179. PMID: 31532967, DOI: 10.1056/nejmsb1900856.Peer-Reviewed Original ResearchBending the cost curve: time series analysis of a value transformation programme at an academic medical centre
Chatfield SC, Volpicelli FM, Adler NM, Kim KL, Jones SA, Francois F, Shah PC, Press RA, Horwitz LI. Bending the cost curve: time series analysis of a value transformation programme at an academic medical centre. BMJ Quality & Safety 2019, 28: 449. PMID: 30877149, PMCID: PMC6860728, DOI: 10.1136/bmjqs-2018-009068.Peer-Reviewed Original ResearchConceptsLength of stayDiagnosis Related GroupsAcademic medical centerHospital mortalityMedical CenterMedical diagnosis related groupsSurgical diagnosis related groupsStudy periodSame-hospital readmissionsCost of careNYU Langone HealthVariable direct costsValue of healthcareSecondary outcomesHigh-value careStudy cohortOutlier patientsHealth outcomesValue careEarly increaseIntervention costsDirect costsHealthcare valueShared Savings ProgramHospitalisation