2021
Circulating Donor Lung-specific Exosome Profiles Enable Noninvasive Monitoring of Acute Rejection in a Rodent Orthotopic Lung Transplantation Model
Habertheuer A, Ram C, Schmierer M, Chatterjee S, Hu R, Freas A, Zielinski P, Rogers W, Silvestro EM, McGrane M, Moore JS, Korutla L, Siddiqui S, Xin Y, Rizi R, Tao J, Kreisel D, Naji A, Ochiya T, Vallabhajosyula P. Circulating Donor Lung-specific Exosome Profiles Enable Noninvasive Monitoring of Acute Rejection in a Rodent Orthotopic Lung Transplantation Model. Transplantation 2021, 106: 754-766. PMID: 33993180, DOI: 10.1097/tp.0000000000003820.Peer-Reviewed Original ResearchConceptsAcute rejectionDonor exosomesExosome profileSyngeneic controlsRat orthotopic lung transplant modelChronic lung allograft dysfunctionOrthotopic lung transplantation modelLung transplant modelPosttransplant time pointsAcute rejection episodesLung allograft dysfunctionLung transplant patientsLung transplant rejectionLung transplantation modelEarly therapeutic interventionMajor risk factorTime-sensitive diagnosisDevelopment of biomarkersAllograft dysfunctionRejection episodesLewis recipientsTransplant patientsPulmonary allograftsRecipient bloodAllogeneic grafts
2018
(492) Donor Lung Specific Exosome Profiles for Noninvasive Monitoring of Acute Rejection in a Rat Orthotopic Left Lung Transplant Model
Habertheuer A, Korutla L, Rostami S, Siddiqui S, Xin Y, Rizi R, Naji A, Zielinski P, Hu R, Ochiya T, Vallabhajosyula P. (492) Donor Lung Specific Exosome Profiles for Noninvasive Monitoring of Acute Rejection in a Rat Orthotopic Left Lung Transplant Model. The Journal Of Heart And Lung Transplantation 2018, 37: s203-s204. DOI: 10.1016/j.healun.2018.01.495.Peer-Reviewed Original Research