2024
Trends in COVID‐19–Attributable Hospitalizations Among Adults With Laboratory‐Confirmed SARS‐CoV‐2—COVID‐NET, June 2020 to September 2023
Taylor C, Whitaker M, Patton M, Melgar M, Kirley P, Kawasaki B, Yousey‐Hindes K, Openo K, Ryan P, Kim S, Como‐Sabetti K, Solhtalab D, Barney G, Tesini B, Moran N, Sutton M, Talbot H, Olsen K, Havers F. Trends in COVID‐19–Attributable Hospitalizations Among Adults With Laboratory‐Confirmed SARS‐CoV‐2—COVID‐NET, June 2020 to September 2023. Influenza And Other Respiratory Viruses 2024, 18: e70021. PMID: 39496579, PMCID: PMC11534501, DOI: 10.1111/irv.70021.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgedAged, 80 and overCOVID-19FemaleHospitalizationHumansMaleMiddle AgedSARS-CoV-2United StatesYoung Adult
2022
Comparison of Influenza and Coronavirus Disease 2019–Associated Hospitalizations Among Children Younger Than 18 Years Old in the United States: FluSurv-NET (October–April 2017–2021) and COVID-NET (October 2020–September 2021)
Delahoy MJ, Ujamaa D, Taylor CA, Cummings C, Anglin O, Holstein R, Milucky J, O’Halloran A, Patel K, Pham H, Whitaker M, Reingold A, Chai SJ, Alden NB, Kawasaki B, Meek J, Yousey-Hindes K, Anderson EJ, Openo KP, Weigel A, Teno K, Reeg L, Leegwater L, Lynfield R, McMahon M, Ropp S, Rudin D, Muse A, Spina N, Bennett NM, Popham K, Billing LM, Shiltz E, Sutton M, Thomas A, Schaffner W, Talbot HK, Crossland MT, McCaffrey K, Hall AJ, Burns E, McMorrow M, Reed C, Havers FP, Garg S. Comparison of Influenza and Coronavirus Disease 2019–Associated Hospitalizations Among Children Younger Than 18 Years Old in the United States: FluSurv-NET (October–April 2017–2021) and COVID-NET (October 2020–September 2021). Clinical Infectious Diseases 2022, 76: e450-e459. PMID: 35594564, PMCID: PMC9129156, DOI: 10.1093/cid/ciac388.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAgedAged, 80 and overChildCOVID-19HospitalizationHumansInfluenza, HumanPandemicsSARS-CoV-2United StatesConceptsCOVID-19-associated hospitalizationInfluenza-associated hospitalization ratesHospitalization ratesIntensive care unit admissionPopulation-based surveillance systemCOVID-19COVID-19 pandemicCare unit admissionInfluenza-associated hospitalizationsComparison of influenzaSARS-CoV-2FluSurv-NETICU admissionUnit admissionHospital outcomesInfluenza seasonRespiratory virusesPediatric deathsPediatric hospitalizationsRespiratory illnessSevere outcomesOngoing COVID-19 pandemicAdolescents 12HospitalizationChildren 5
2021
Rates of Influenza-Associated Hospitalization, Intensive Care Unit Admission, and In-Hospital Death by Race and Ethnicity in the United States From 2009 to 2019
O’Halloran A, Holstein R, Cummings C, Kirley P, Alden NB, Yousey-Hindes K, Anderson EJ, Ryan P, Kim S, Lynfield R, McMullen C, Bennett NM, Spina N, Billing LM, Sutton M, Schaffner W, Talbot HK, Price A, Fry AM, Reed C, Garg S. Rates of Influenza-Associated Hospitalization, Intensive Care Unit Admission, and In-Hospital Death by Race and Ethnicity in the United States From 2009 to 2019. JAMA Network Open 2021, 4: e2121880. PMID: 34427679, PMCID: PMC8385599, DOI: 10.1001/jamanetworkopen.2021.21880.Peer-Reviewed Original ResearchConceptsInfluenza-associated hospitalizationsIntensive care unit admissionCare unit admissionCross-sectional studyHospitalization ratesPacific Islander childrenHospital deathICU admissionUnit admissionInfluenza seasonMAIN OUTCOMELaboratory-confirmed influenza-associated hospitalizationsAge groupsAge-adjusted hospitalization ratesHospital death rateICU admission rateInfluenza-associated diseaseInfluenza-associated outcomesIn-Hospital DeathSevere influenza diseaseHispanic childrenPopulation-based surveillanceWhite personsAlaska NativesAge-stratified rates
2020
Acute Cardiovascular Events Associated With Influenza in Hospitalized Adults : A Cross-sectional Study.
Chow EJ, Rolfes MA, O'Halloran A, Anderson EJ, Bennett NM, Billing L, Chai S, Dufort E, Herlihy R, Kim S, Lynfield R, McMullen C, Monroe ML, Schaffner W, Spencer M, Talbot HK, Thomas A, Yousey-Hindes K, Reed C, Garg S. Acute Cardiovascular Events Associated With Influenza in Hospitalized Adults : A Cross-sectional Study. Annals Of Internal Medicine 2020, 173: 605-613. PMID: 32833488, PMCID: PMC8097760, DOI: 10.7326/m20-1509.Peer-Reviewed Original ResearchConceptsAcute ischemic heart diseaseAcute heart failureAcute cardiovascular eventsLaboratory-confirmed influenzaCardiovascular eventsCross-sectional studyInfluenza vaccinationDischarge codesInfluenza testingChronic conditionsTobacco useInfluenza Hospitalization Surveillance NetworkInfluenza antiviral medicationsMedical record abstractionIschemic heart diseasePopulation-based studyAnnual influenza epidemicsLogistic regression modelsCommon such eventsRace/ethnicityPractitioner ordersHospitalized adultsAntiviral medicationsHeart failureInfluenza seasonRespiratory and Nonrespiratory Diagnoses Associated With Influenza in Hospitalized Adults
Chow EJ, Rolfes MA, O’Halloran A, Alden NB, Anderson EJ, Bennett NM, Billing L, Dufort E, Kirley PD, George A, Irizarry L, Kim S, Lynfield R, Ryan P, Schaffner W, Talbot HK, Thomas A, Yousey-Hindes K, Reed C, Garg S. Respiratory and Nonrespiratory Diagnoses Associated With Influenza in Hospitalized Adults. JAMA Network Open 2020, 3: e201323. PMID: 32196103, PMCID: PMC7084169, DOI: 10.1001/jamanetworkopen.2020.1323.Peer-Reviewed Original ResearchConceptsLaboratory-confirmed influenzaRespiratory diagnosesInfluenza seasonAcute diagnosisInfluenza Hospitalization Surveillance NetworkPositive influenza test resultsRevision discharge diagnosis codesSeasonal influenza virus infectionCommon acute diagnosesEarly antiviral treatmentAcute kidney injuryMedical record abstractionPatient demographic characteristicsDischarge diagnosis codesBurden of infectionInfluenza virus infectionInfluenza test resultsCross-sectional studyTranscription-polymerase chain reactionIndirect fluorescent stainingInternational Statistical ClassificationSurveillance networkRelated Health ProblemsFluSurv-NETHospital outcomes
2017
Impact of pregnancy on observed sex disparities among adults hospitalized with laboratory‐confirmed influenza, FluSurv‐NET, 2010‐2012
Kline K, Hadler JL, Yousey‐Hindes K, Niccolai L, Kirley PD, Miller L, Anderson EJ, Monroe ML, Bohm SR, Lynfield R, Bargsten M, Zansky SM, Lung K, Thomas AR, Brady D, Schaffner W, Reed G, Garg S. Impact of pregnancy on observed sex disparities among adults hospitalized with laboratory‐confirmed influenza, FluSurv‐NET, 2010‐2012. Influenza And Other Respiratory Viruses 2017, 11: 404-411. PMID: 28703414, PMCID: PMC5596517, DOI: 10.1111/irv.12465.Peer-Reviewed Original ResearchConceptsIncidence rate ratiosInfluenza-associated hospitalizationsMale incidence rate ratiosPregnant womenLaboratory-confirmed influenza-associated hospitalizationsFemale incidence rate ratiosLaboratory-confirmed influenza casesLaboratory-confirmed influenzaLikelihood of vaccinationPopulation-based surveillanceNon-pregnant womenImpact of pregnancyNon-pregnant counterpartsCensus tract-level povertyObserved sex disparityGroup of womenTract-level povertyRace/ethnicityPregnant adult femalesFluSurv-NETHospitalized femalesInfluenza seasonAdult casesVaccination priorityVaccination rates
2015
Identification of population at risk for future Clostridium difficile infection following hospital discharge to be targeted for vaccine trials
Baggs J, Yousey-Hindes K, Ashley ED, Meek J, Dumyati G, Cohen J, Wise ME, McDonald LC, Lessa FC. Identification of population at risk for future Clostridium difficile infection following hospital discharge to be targeted for vaccine trials. Vaccine 2015, 33: 6241-6249. PMID: 26450660, PMCID: PMC4702247, DOI: 10.1016/j.vaccine.2015.09.078.Peer-Reviewed Original ResearchConceptsEmerging Infections ProgramHigh-risk groupRisk groupsRisk scoreIndex hospitalizationHospital dischargeDerivation cohortVaccine trialsValidation cohortDifficile infectionCox proportional hazards modelRisk of CDIAcute care hospitalizationIdentification of patientsClostridium difficile infectionHospital discharge dataNumber of hospitalizationsLow-risk groupProportional hazards modelLarge academic centerAdmission diagnosisPrimary outcomeInpatient stayPatient populationPharmacy data
2014
Comparing Clinical Characteristics Between Hospitalized Adults With Laboratory-Confirmed Influenza A and B Virus Infection
Su S, Chaves SS, Perez A, D'Mello T, Kirley PD, Yousey-Hindes K, Farley MM, Harris M, Sharangpani R, Lynfield R, Morin C, Hancock EB, Zansky S, Hollick GE, Fowler B, McDonald-Hamm C, Thomas A, Horan V, Lindegren ML, Schaffner W, Price A, Bandyopadhyay A, Fry AM. Comparing Clinical Characteristics Between Hospitalized Adults With Laboratory-Confirmed Influenza A and B Virus Infection. Clinical Infectious Diseases 2014, 59: 252-255. PMID: 24748521, DOI: 10.1093/cid/ciu269.Peer-Reviewed Original ResearchInfluenza‐related hospitalization of adults associated with low census tract socioeconomic status and female sex in New Haven County, Connecticut, 2007‐2011
Tam K, Yousey‐Hindes K, Hadler JL. Influenza‐related hospitalization of adults associated with low census tract socioeconomic status and female sex in New Haven County, Connecticut, 2007‐2011. Influenza And Other Respiratory Viruses 2014, 8: 274-281. PMID: 24382111, PMCID: PMC4181475, DOI: 10.1111/irv.12231.Peer-Reviewed Original ResearchConceptsAge-adjusted incidenceInfluenza seasonNeighborhood socioeconomic statusSocioeconomic statusFemale sexVaccination effortsCensus tract socioeconomic statusFuture influenza vaccination effortsActive population-based surveillanceLower neighborhood socioeconomic statusSES measuresHospitalizations of adultsInfluenza-related hospitalizationsPopulation-based surveillanceInfluenza hospitalizationsInfluenza infectionCostly complicationRelative riskFemale incidenceHigh riskHigh incidenceHospitalizationNew Haven CountyResidential addressesAge groups
2013
Heavy alcohol use as a risk factor for severe outcomes among adults hospitalized with laboratory-confirmed influenza, 2005–2012
Greenbaum A, Chaves S, Perez A, Aragon D, Bandyopadhyay A, Bennett N, Fowler B, Hancock E, Lynfield R, McDonald-Hamm C, Reingold A, Ryan P, Schaffner W, Sharangpani R, Spencer M, Thomas A, Yousey-Hindes K, Zansky S, Finelli L. Heavy alcohol use as a risk factor for severe outcomes among adults hospitalized with laboratory-confirmed influenza, 2005–2012. Infection 2013, 42: 165-170. PMID: 24243481, DOI: 10.1007/s15010-013-0534-8.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgedAged, 80 and overAlcoholismHospitalizationHumansInfluenza, HumanMaleMiddle AgedRisk FactorsYoung Adult
2012
Increase in Rates of Hospitalization Due to Laboratory-Confirmed Influenza Among Children and Adults During the 2009–10 Influenza Pandemic
Cox CM, D'Mello T, Perez A, Reingold A, Gershman K, Yousey-Hindes K, Arnold KE, Farley MM, Ryan P, Lynfield R, Morin C, Baumbach J, Hancock EB, Zansky S, Bennett NM, Thomas A, Schaffner W, Finelli L, Network F. Increase in Rates of Hospitalization Due to Laboratory-Confirmed Influenza Among Children and Adults During the 2009–10 Influenza Pandemic. The Journal Of Infectious Diseases 2012, 206: 1350-1358. PMID: 23002448, DOI: 10.1093/infdis/jis517.Peer-Reviewed Original ResearchConceptsLaboratory-confirmed influenzaPrevious influenza seasonRate of hospitalizationInfluenza seasonEmerging Infections Program NetworkInfections Program NetworkPopulation-based surveillancePandemic of influenzaAdult age groupsUS Census Bureau dataMean rateH1N1 infectionHospitalization DueHospitalization ratesIncidence rateInfluenza pandemicAge groupsHospitalizationInfluenzaMonthsCensus Bureau dataSurveillanceAdultsEpisodesChildrenReduced Influenza Antiviral Treatment Among Children and Adults Hospitalized With Laboratory-Confirmed Influenza Infection in the Year After the 2009 Pandemic
Garg S, Chaves SS, Pérez A, D'Mello T, Gershman K, Meek J, Yousey-Hindes K, Arnold KE, Farley MM, Tengelsen L, Ryan P, Sharangpani R, Lynfield R, Morin C, Baumbach J, Hancock EB, Zansky S, Bennett NM, Fowler B, Bradley K, Thomas A, Cooper T, Schaffner W, Boulton R, Finelli L, Fry AM. Reduced Influenza Antiviral Treatment Among Children and Adults Hospitalized With Laboratory-Confirmed Influenza Infection in the Year After the 2009 Pandemic. Clinical Infectious Diseases 2012, 55: e18-e21. PMID: 22543024, DOI: 10.1093/cid/cis442.Peer-Reviewed Original Research
2011
Description of Antiviral Treatment Among Adults Hospitalized With Influenza Before and During the 2009 Pandemic: United States, 2005–2009
Doshi S, Kamimoto L, Finelli L, Perez A, Reingold A, Gershman K, Yousey-Hindes K, Arnold K, Ryan P, Lynfield R, Morin C, Baumbach J, Hancock EB, Bennett NM, Zansky S, Thomas A, Schaffner W, Fry AM. Description of Antiviral Treatment Among Adults Hospitalized With Influenza Before and During the 2009 Pandemic: United States, 2005–2009. The Journal Of Infectious Diseases 2011, 204: 1848-1856. PMID: 22013219, DOI: 10.1093/infdis/jir648.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgedAged, 80 and overAmantadineAntiviral AgentsDrug Therapy, CombinationFemaleGuideline AdherenceHospitalizationHumansInfluenza A Virus, H1N1 SubtypeInfluenza, HumanMaleMiddle AgedOdds RatioOseltamivirPandemicsPractice Guidelines as TopicPractice Patterns, Physicians'PregnancyPregnancy Complications, InfectiousRimantadineUnited StatesYoung AdultZanamivirConceptsAntiviral treatmentPregnant womenHospitalized adultsActive population-based surveillanceEmerging Infections ProgramLaboratory-confirmed influenzaMedical record reviewPopulation-based surveillanceAntiviral recommendationsAntiviral useRecord reviewIllness onsetInfections ProgramInfluenza pandemicAntiviral agentsInfluenzaNegative predictorAdultsTreatmentWomenPandemicPatientsPregnancyCliniciansPersons
2009
Peridomestic Lyme Disease Prevention Results of a Population-Based Case–Control Study
Connally NP, Durante AJ, Yousey-Hindes KM, Meek JI, Nelson RS, Heimer R. Peridomestic Lyme Disease Prevention Results of a Population-Based Case–Control Study. American Journal Of Preventive Medicine 2009, 37: 201-206. PMID: 19595558, DOI: 10.1016/j.amepre.2009.04.026.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgedAged, 80 and overAnimalsCase-Control StudiesChildChild, PreschoolConnecticutEnvironment DesignEnvironmental ExposureFemaleHumansHygieneInfantLogistic ModelsLyme DiseaseMaleMatched-Pair AnalysisMiddle AgedPopulation SurveillanceProspective StudiesResidence CharacteristicsRisk FactorsSurveys and QuestionnairesTicksYoung AdultConceptsCase-control studyLyme diseaseDisease prevention initiativesConditional logistic regressionDisease prevention measuresErythema migransPotential confoundersRecreational exposureLogistic regressionProspective ageDiseaseCase onsetPrevention resultsPrevention measuresPersonal protectionRiskHoursConfoundersMigransTicksInfectionStudyConnecticut communitiesMonths