2024
Trends in COVID‐19–Attributable Hospitalizations Among Adults With Laboratory‐Confirmed SARS‐CoV‐2—COVID‐NET, June 2020 to September 2023
Taylor C, Whitaker M, Patton M, Melgar M, Kirley P, Kawasaki B, Yousey‐Hindes K, Openo K, Ryan P, Kim S, Como‐Sabetti K, Solhtalab D, Barney G, Tesini B, Moran N, Sutton M, Talbot H, Olsen K, Havers F. Trends in COVID‐19–Attributable Hospitalizations Among Adults With Laboratory‐Confirmed SARS‐CoV‐2—COVID‐NET, June 2020 to September 2023. Influenza And Other Respiratory Viruses 2024, 18: e70021. PMID: 39496579, PMCID: PMC11534501, DOI: 10.1111/irv.70021.Peer-Reviewed Original Research
2023
COVID-19–Associated Hospitalizations Among U.S. Adults Aged ≥65 Years — COVID-NET, 13 States, January–August 2023
Taylor C, Patel K, Patton M, Reingold A, Kawasaki B, Meek J, Openo K, Ryan P, Falkowski A, Bye E, Plymesser K, Spina N, Tesini B, Moran N, Sutton M, Talbot H, George A, Havers F, Team C, Team C, Kirley P, Armistead I, Yousey-Hindes K, Oosmanally N, Monroe M, Henderson J, D’Heilly P, Hancock E, Barney G, Bushey S, Billing L, Abdullah N, Schaffner W, Mendez E. COVID-19–Associated Hospitalizations Among U.S. Adults Aged ≥65 Years — COVID-NET, 13 States, January–August 2023. MMWR Morbidity And Mortality Weekly Report 2023, 72: 1089-1094. PMID: 37796744, PMCID: PMC10564325, DOI: 10.15585/mmwr.mm7240a3.Peer-Reviewed Original ResearchMeSH KeywordsAdultCOVID-19HospitalizationHumansIntensive Care UnitsSARS-CoV-2United StatesVaccinationConceptsCOVID-19-associated hospitalizationCOVID-19-Associated Hospitalization Surveillance NetworkCOVID-19-associated hospitalization ratesHospitalization ratesAge groupsIntensive care unit admissionMultiple underlying conditionsSevere COVID-19 diseasePromote early treatmentPositive SARS-CoV-2 testSARS-CoV-2 infectionPrevent SARS-CoV-2 infectionYounger age groupsClinical characteristicsUnit admissionUnderlying conditionEarly treatmentSARS-CoV-2 testingIncreased riskSevere COVID-19-associated outcomesSevere outcomesCOVID-19 hospitalizationElevated riskCOVID-19 diseaseBivalent vaccineSeverity of influenza-associated hospitalisations by influenza virus type and subtype in the USA, 2010–19: a repeated cross-sectional study
Sumner K, Masalovich S, O’Halloran A, Holstein R, Reingold A, Kirley P, Alden N, Herlihy R, Meek J, Yousey-Hindes K, Anderson E, Openo K, Monroe M, Leegwater L, Henderson J, Lynfield R, McMahon M, McMullen C, Angeles K, Spina N, Engesser K, Bennett N, Felsen C, Lung K, Shiltz E, Thomas A, Talbot H, Schaffner W, Swain A, George A, Rolfes M, Reed C, Garg S. Severity of influenza-associated hospitalisations by influenza virus type and subtype in the USA, 2010–19: a repeated cross-sectional study. The Lancet Microbe 2023, 4: e903-e912. PMID: 37769676, PMCID: PMC10872935, DOI: 10.1016/s2666-5247(23)00187-8.Peer-Reviewed Original ResearchConceptsInfluenza virus typeInfluenza-associated hospitalisationsInfluenza seasonInfluenza B virusICU admissionMechanical ventilationSevere outcomesOdds ratioVirus typeFluSurv-NETECMO useInfluenza vaccineB virusVirus infectionLaboratory-confirmed influenza virus infectionInfluenza Hospitalization Surveillance NetworkInfluenza B virus infectionPopulation-based surveillance systemComplete chart reviewEarly antiviral treatmentHospital-onset casesInfluenza-associated outcomesRepeated cross-sectional studyInfluenza vaccination statusB virus infection
2022
Trends in disparities in COVID hospitalizations among community‐dwelling residents of two counties in Connecticut, before and after vaccine introduction, March 2020–September 2021
McWilliams C, Bothwell L, Yousey‐Hindes K, Hadler J. Trends in disparities in COVID hospitalizations among community‐dwelling residents of two counties in Connecticut, before and after vaccine introduction, March 2020–September 2021. Influenza And Other Respiratory Viruses 2022, 17: e13082. PMID: 36509459, PMCID: PMC9835416, DOI: 10.1111/irv.13082.Peer-Reviewed Original ResearchMeSH KeywordsChildConnecticutCOVID-19COVID-19 VaccinesHospitalizationHumansIndependent LivingSocioeconomic FactorsUnited StatesConceptsCOVID-19 hospitalizationNon-Hispanic blacksGeocoded residential addressesAge-adjusted incidenceNon-Hispanic whitesHispanic/LatinxVaccination ratesLaboratory-confirmed COVID-19Residential addressesSocioeconomic statusSurveillance Network databaseCommunity-dwelling residentsNon-institutionalized personsIntroduction of vaccinesLow socioeconomic statusCensus tract measuresRace/ethnicityLower SES groupsVaccine registryVaccine introductionVaccination levelsHospitalizationVaccine rolloutDelta wavesSES disparitiesVital Signs: Influenza Hospitalizations and Vaccination Coverage by Race and Ethnicity—United States, 2009–10 Through 2021–22 Influenza Seasons
Black C, O’Halloran A, Hung M, Srivastav A, Lu P, Garg S, Jhung M, Fry A, Jatlaoui T, Davenport E, Burns E, Network I, Network I, Reingold A, Alden N, Yousey-Hindes K, Anderson E, Ryan P, Kim S, McMahon M, Bleecker M, Spina N, Bennett N, Lung K, Sutton M, Schaffner W, Talbot H, Crossland M, Reed C, Holstein R, Ujamaa D, Cummings C. Vital Signs: Influenza Hospitalizations and Vaccination Coverage by Race and Ethnicity—United States, 2009–10 Through 2021–22 Influenza Seasons. MMWR Morbidity And Mortality Weekly Report 2022, 71: 1366-1373. PMID: 36302226, PMCID: PMC9620569, DOI: 10.15585/mmwr.mm7143e1.Peer-Reviewed Original ResearchConceptsInfluenza vaccination coverageBehavioral Risk Factor Surveillance SystemVaccination coverageHealth care providersInfluenza seasonInfluenza hospitalizationsInfluenza vaccinationAsian adultsCare providersHispanic adultsLaboratory-confirmed influenza-associated hospitalizationsDisease severityLow influenza vaccination coverageNon-Hispanic Asian adultsPersonal health care providerHealth care access barriersNon-Hispanic white personsRisk Factor Surveillance SystemInfluenza disease severityInfluenza hospitalization ratesPatient vaccination statusInfluenza-associated hospitalizationsPopulation-based surveillanceRoutine medical checkupVaccination coverage dataComparison of Influenza and Coronavirus Disease 2019–Associated Hospitalizations Among Children Younger Than 18 Years Old in the United States: FluSurv-NET (October–April 2017–2021) and COVID-NET (October 2020–September 2021)
Delahoy MJ, Ujamaa D, Taylor CA, Cummings C, Anglin O, Holstein R, Milucky J, O’Halloran A, Patel K, Pham H, Whitaker M, Reingold A, Chai SJ, Alden NB, Kawasaki B, Meek J, Yousey-Hindes K, Anderson EJ, Openo KP, Weigel A, Teno K, Reeg L, Leegwater L, Lynfield R, McMahon M, Ropp S, Rudin D, Muse A, Spina N, Bennett NM, Popham K, Billing LM, Shiltz E, Sutton M, Thomas A, Schaffner W, Talbot HK, Crossland MT, McCaffrey K, Hall AJ, Burns E, McMorrow M, Reed C, Havers FP, Garg S. Comparison of Influenza and Coronavirus Disease 2019–Associated Hospitalizations Among Children Younger Than 18 Years Old in the United States: FluSurv-NET (October–April 2017–2021) and COVID-NET (October 2020–September 2021). Clinical Infectious Diseases 2022, 76: e450-e459. PMID: 35594564, PMCID: PMC9129156, DOI: 10.1093/cid/ciac388.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAgedAged, 80 and overChildCOVID-19HospitalizationHumansInfluenza, HumanPandemicsSARS-CoV-2United StatesConceptsCOVID-19-associated hospitalizationInfluenza-associated hospitalization ratesHospitalization ratesIntensive care unit admissionPopulation-based surveillance systemCOVID-19COVID-19 pandemicCare unit admissionInfluenza-associated hospitalizationsComparison of influenzaSARS-CoV-2FluSurv-NETICU admissionUnit admissionHospital outcomesInfluenza seasonRespiratory virusesPediatric deathsPediatric hospitalizationsRespiratory illnessSevere outcomesOngoing COVID-19 pandemicAdolescents 12HospitalizationChildren 5
2021
Racial and Ethnic Disparities in Rates of COVID-19–Associated Hospitalization, Intensive Care Unit Admission, and In-Hospital Death in the United States From March 2020 to February 2021
Acosta AM, Garg S, Pham H, Whitaker M, Anglin O, O’Halloran A, Milucky J, Patel K, Taylor C, Wortham J, Chai SJ, Kirley PD, Alden NB, Kawasaki B, Meek J, Yousey-Hindes K, Anderson EJ, Openo KP, Weigel A, Monroe ML, Ryan P, Reeg L, Kohrman A, Lynfield R, Bye E, Torres S, Salazar-Sanchez Y, Muse A, Barney G, Bennett NM, Bushey S, Billing L, Shiltz E, Sutton M, Abdullah N, Talbot HK, Schaffner W, Ortega J, Price A, Fry AM, Hall A, Kim L, Havers FP. Racial and Ethnic Disparities in Rates of COVID-19–Associated Hospitalization, Intensive Care Unit Admission, and In-Hospital Death in the United States From March 2020 to February 2021. JAMA Network Open 2021, 4: e2130479. PMID: 34673962, PMCID: PMC8531997, DOI: 10.1001/jamanetworkopen.2021.30479.Peer-Reviewed Original ResearchConceptsCOVID-19-associated hospitalizationIntensive care unit admissionCare unit admissionSevere COVID-19Age-adjusted ratesICU admissionHospital deathUnit admissionWhite personsPacific Islander personsLaboratory-confirmed COVID-19-associated hospitalizationsAlaska NativesCOVID-19Positive SARS-CoV-2 testCOVID-19 Associated HospitalizationsEthnic disparitiesCOVID-19-Associated Hospitalization Surveillance NetworkSARS-CoV-2 testNon-Hispanic white personsIn-Hospital DeathRate ratioCross-sectional studyNon-Hispanic American IndianEthnic minority groupsNon-Hispanic blacksCensus tract socioeconomic indicators and COVID-19-associated hospitalization rates—COVID-NET surveillance areas in 14 states, March 1–April 30, 2020
Wortham JM, Meador SA, Hadler JL, Yousey-Hindes K, See I, Whitaker M, O’Halloran A, Milucky J, Chai SJ, Reingold A, Alden NB, Kawasaki B, Anderson EJ, Openo KP, Weigel A, Monroe ML, Ryan PA, Kim S, Reeg L, Lynfield R, McMahon M, Sosin DM, Eisenberg N, Rowe A, Barney G, Bennett NM, Bushey S, Billing LM, Shiltz J, Sutton M, West N, Talbot HK, Schaffner W, McCaffrey K, Spencer M, Kambhampati AK, Anglin O, Piasecki AM, Holstein R, Hall AJ, Fry AM, Garg S, Kim L. Census tract socioeconomic indicators and COVID-19-associated hospitalization rates—COVID-NET surveillance areas in 14 states, March 1–April 30, 2020. PLOS ONE 2021, 16: e0257622. PMID: 34559838, PMCID: PMC8462704, DOI: 10.1371/journal.pone.0257622.Peer-Reviewed Original ResearchConceptsCOVID-19-associated hospitalizationHigh-poverty census tractsHospitalization ratesFederal poverty levelNon-Hispanic black personsNon-Hispanic white personsHispanic personsAge-adjusted hospitalization ratesPopulation-based surveillanceLow-poverty census tractsCensus tractsPublic health practiceClinical Trends Among U.S. Adults Hospitalized With COVID-19, March to December 2020
Garg S, Patel K, Pham H, Whitaker M, O'Halloran A, Milucky J, Anglin O, Kirley PD, Reingold A, Kawasaki B, Herlihy R, Yousey-Hindes K, Maslar A, Anderson EJ, Openo KP, Weigel A, Teno K, Ryan PA, Monroe ML, Reeg L, Kim S, Como-Sabetti K, Bye E, Davis S, Eisenberg N, Muse A, Barney G, Bennett NM, Felsen CB, Billing L, Shiltz J, Sutton M, Abdullah N, Talbot HK, Schaffner W, Hill M, Chatelain R, Wortham J, Taylor C, Hall A, Fry AM, Kim L, Havers FP. Clinical Trends Among U.S. Adults Hospitalized With COVID-19, March to December 2020. Annals Of Internal Medicine 2021, 174: m21-1991. PMID: 34370517, PMCID: PMC8381761, DOI: 10.7326/m21-1991.Peer-Reviewed Original ResearchMeSH KeywordsAdenosine MonophosphateAdolescentAdrenal Cortex HormonesAdultAge DistributionAgedAlanineAntiviral AgentsCOVID-19Critical CareCross-Sectional StudiesFemaleHospitalizationHumansIntensive Care UnitsLength of StayMaleMiddle AgedPandemicsRespiration, ArtificialSARS-CoV-2United StatesVasoconstrictor AgentsYoung AdultConceptsICU admissionClinical trendsMechanical ventilationCOVID-19COVID-19-associated hospitalizationIntensive care unit admissionLaboratory-confirmed COVID-19U.S. adultsNon-Hispanic black personsCare unit admissionHospital death rateNoninvasive respiratory supportUse of remdesivirPercentage of interventionsCross-sectional studyCOVID-19 vaccineNon-Hispanic whitesSystemic corticosteroidsUnit admissionVasopressor useHospitalized adultsRespiratory supportCase patientsMedian ageSubstantial morbidityRates of Influenza-Associated Hospitalization, Intensive Care Unit Admission, and In-Hospital Death by Race and Ethnicity in the United States From 2009 to 2019
O’Halloran A, Holstein R, Cummings C, Kirley P, Alden NB, Yousey-Hindes K, Anderson EJ, Ryan P, Kim S, Lynfield R, McMullen C, Bennett NM, Spina N, Billing LM, Sutton M, Schaffner W, Talbot HK, Price A, Fry AM, Reed C, Garg S. Rates of Influenza-Associated Hospitalization, Intensive Care Unit Admission, and In-Hospital Death by Race and Ethnicity in the United States From 2009 to 2019. JAMA Network Open 2021, 4: e2121880. PMID: 34427679, PMCID: PMC8385599, DOI: 10.1001/jamanetworkopen.2021.21880.Peer-Reviewed Original ResearchConceptsInfluenza-associated hospitalizationsIntensive care unit admissionCare unit admissionCross-sectional studyHospitalization ratesPacific Islander childrenHospital deathICU admissionUnit admissionInfluenza seasonMAIN OUTCOMELaboratory-confirmed influenza-associated hospitalizationsAge groupsAge-adjusted hospitalization ratesHospital death rateICU admission rateInfluenza-associated diseaseInfluenza-associated outcomesIn-Hospital DeathSevere influenza diseaseHispanic childrenPopulation-based surveillanceWhite personsAlaska NativesAge-stratified rates
2020
Risk Factors for Coronavirus Disease 2019 (COVID-19)–Associated Hospitalization: COVID-19–Associated Hospitalization Surveillance Network and Behavioral Risk Factor Surveillance System
Ko JY, Danielson ML, Town M, Derado G, Greenlund KJ, Kirley PD, Alden NB, Yousey-Hindes K, Anderson EJ, Ryan PA, Kim S, Lynfield R, Torres SM, Barney GR, Bennett NM, Sutton M, Talbot HK, Hill M, Hall AJ, Fry AM, Garg S, Kim L, Whitaker M, O’Halloran A, Holstein R, Garvin W, Chai S, Kawasaki B, Meek J, Openo K, Monroe M, Henderson J, Como-Sabetti K, Davis S, Spina N, Felsen C, West N, Schaffner W, George A. Risk Factors for Coronavirus Disease 2019 (COVID-19)–Associated Hospitalization: COVID-19–Associated Hospitalization Surveillance Network and Behavioral Risk Factor Surveillance System. Clinical Infectious Diseases 2020, 72: e695-e703. PMID: 32945846, PMCID: PMC7543371, DOI: 10.1093/cid/ciaa1419.Peer-Reviewed Original ResearchConceptsCOVID-19-Associated Hospitalization Surveillance NetworkCOVID-19-associated hospitalizationChronic kidney diseaseHospitalization ratesRace/ethnicitySevere obesityKidney diseaseRisk factorsMedical conditionsLaboratory-confirmed COVID-19Chronic obstructive pulmonary diseaseBehavioral Risk Factor Surveillance SystemRisk Factor Surveillance SystemHigher hospitalization riskRace/ethnicity strataHistory of strokeObstructive pulmonary diseaseUnderlying medical conditionsCoronary artery diseaseHigher hospitalization ratesCommunity-dwelling adultsCoronavirus disease 2019Surveillance networkPoisson regression modelsSurveillance systemRisk Factors for Intensive Care Unit Admission and In-hospital Mortality Among Hospitalized Adults Identified through the US Coronavirus Disease 2019 (COVID-19)-Associated Hospitalization Surveillance Network (COVID-NET)
Kim L, Garg S, O’Halloran A, Whitaker M, Pham H, Anderson EJ, Armistead I, Bennett NM, Billing L, Como-Sabetti K, Hill M, Kim S, Monroe ML, Muse A, Reingold AL, Schaffner W, Sutton M, Talbot HK, Torres SM, Yousey-Hindes K, Holstein R, Cummings C, Brammer L, Hall AJ, Fry AM, Langley GE. Risk Factors for Intensive Care Unit Admission and In-hospital Mortality Among Hospitalized Adults Identified through the US Coronavirus Disease 2019 (COVID-19)-Associated Hospitalization Surveillance Network (COVID-NET). Clinical Infectious Diseases 2020, 72: e206-e214. PMID: 32674114, PMCID: PMC7454425, DOI: 10.1093/cid/ciaa1012.Peer-Reviewed Original ResearchConceptsIntensive care unit admissionCare unit admissionHospital mortalityICU admissionUnit admissionMale sexRisk factorsAge 50Independent factorsCOVID-19-related complicationsLaboratory-confirmed COVID-19Surveillance networkCoronavirus disease 2019 (COVID-19) casesInvasive mechanical ventilationIn-Hospital MortalityChronic lung diseaseAcute care hospitalsCoronavirus disease 2019COVID-19Rigorous hand hygieneRenal diseaseMechanical ventilationMultivariable analysisLung diseaseSevere outcomesRespiratory and Nonrespiratory Diagnoses Associated With Influenza in Hospitalized Adults
Chow EJ, Rolfes MA, O’Halloran A, Alden NB, Anderson EJ, Bennett NM, Billing L, Dufort E, Kirley PD, George A, Irizarry L, Kim S, Lynfield R, Ryan P, Schaffner W, Talbot HK, Thomas A, Yousey-Hindes K, Reed C, Garg S. Respiratory and Nonrespiratory Diagnoses Associated With Influenza in Hospitalized Adults. JAMA Network Open 2020, 3: e201323. PMID: 32196103, PMCID: PMC7084169, DOI: 10.1001/jamanetworkopen.2020.1323.Peer-Reviewed Original ResearchConceptsLaboratory-confirmed influenzaRespiratory diagnosesInfluenza seasonAcute diagnosisInfluenza Hospitalization Surveillance NetworkPositive influenza test resultsRevision discharge diagnosis codesSeasonal influenza virus infectionCommon acute diagnosesEarly antiviral treatmentAcute kidney injuryMedical record abstractionPatient demographic characteristicsDischarge diagnosis codesBurden of infectionInfluenza virus infectionInfluenza test resultsCross-sectional studyTranscription-polymerase chain reactionIndirect fluorescent stainingInternational Statistical ClassificationSurveillance networkRelated Health ProblemsFluSurv-NETHospital outcomesSpatial and temporal clustering of patients hospitalized with laboratory-confirmed influenza in the United States
Sloan C, Chandrasekhar R, Mitchel E, Ndi D, Miller L, Thomas A, Bennett NM, Chai S, Spencer M, Eckel S, Spina N, Monroe M, Anderson EJ, Lynfield R, Yousey-Hindes K, Bargsten M, Zansky S, Lung K, Schroeder M, N Cummings C, Garg S, Schaffner W, Lindegren ML. Spatial and temporal clustering of patients hospitalized with laboratory-confirmed influenza in the United States. Epidemics 2020, 31: 100387. PMID: 32371346, DOI: 10.1016/j.epidem.2020.100387.Peer-Reviewed Original ResearchConceptsRelative riskHospitalization burdenInfluenza Hospitalization Surveillance NetworkSocioeconomic factorsLaboratory-confirmed influenzaTiming of influenzaScan statistics analysisInfluenza seasonDisease burdenEpidemic timingSurveillance dataInfluenzaPandemic yearSpatial scan statisticSurveillance networkBurdenLocal socioeconomic factorsUnited StatesEpidemic intensityYearsPhase synchronyNational patternsPatientsSocioeconomicsFactors
2019
Effects of Influenza Vaccination in the United States During the 2017–2018 Influenza Season
Rolfes MA, Flannery B, Chung JR, O’Halloran A, Garg S, Belongia EA, Gaglani M, Zimmerman RK, Jackson ML, Monto AS, Alden NB, Anderson E, Bennett NM, Billing L, Eckel S, Kirley PD, Lynfield R, Monroe ML, Spencer M, Spina N, Talbot HK, Thomas A, Torres SM, Yousey-Hindes K, Singleton JA, Patel M, Reed C, Fry AM, McLean H, King J, Nowalk M, Balasubramani G, Bear T, Hickey R, Williams J, Reis E, Moehling K, Eng H, Jackson L, Smith M, Raiyani C, Clipper L, Murthy K, Chen W, Reis M, Petrie J, Malosh R, McSpadden E, Segaloff H, Cheng C, Truscon R, Johnson E, Lamerato L, Rosenblum B, Ford S, Johnson M, Raviotta J, Sax T, Steele J, Susick M, Chabra R, Garofolo E, Iozzi P, Kevish B, Middleton D, Urbanski L, Ponder T, Crumbaker T, Iosefo I, Sleeth P, Gandy V, Bounds K, Kylberg M, Rao A, Fader R, Walker K, Volz M, Ray J, Price D, Thomas J, Wehbe-Janek H, Beeram M, Boyd J, Walkowiak J, Probe R, Couchman G, Motakef S, Arroliga A, Kaniclides A, Bouldin E, Baker C, Berke K, Smith M, Rajesh N, Alleman E, Bauer S, Groesbeck M, Brundidge K, Hafeez N, Jackson J, Anastasia I, Kadoo G, Petnic S, Ryan A, Maslar A, Meek J, Chen R, Stephens S, Thomas S, Segler S, Openo K, Fawcett E, Farley M, Martin A, Ryan P, Sunkel R, Lutich T, Perlmutter R, Grace B, Blood T, Zerrlaut C, McMahon M, Strain A, Christensen J, Angeles K, Butler L, Khanlian S, Mansmann R, McMullen C, Pradhan E, Manzi K, Felsen C, Gaitan M, Long K, Fisher N, Hawley E, O’Shaughnessy R, Scott M, Crawford C, Schaffner W, Markus T, Leib K, Dyer K, Santibanez T, Zhai Y, Lu P, Srivastav A, Hung M. Effects of Influenza Vaccination in the United States During the 2017–2018 Influenza Season. Clinical Infectious Diseases 2019, 69: 1845-1853. PMID: 30715278, PMCID: PMC7188082, DOI: 10.1093/cid/ciz075.Peer-Reviewed Original ResearchConceptsInfluenza-associated illnessVaccine effectivenessInfluenza vaccinationInfluenza seasonMedical visitsCurrent influenza vaccinationInfluenza-associated outcomesInfluenza vaccine coverageInfluenza vaccine effectivenessLaboratory-confirmed influenzaTest-negative designInfluenza virus infectionAge-specific estimatesInfluenza B.Vaccine coverageDisease burdenVirus infectionSubstantial burdenAmbulatory settingVaccinationHospitalizationImproved vaccinesInfluenzaIllnessVisits
2018
Clinical Features and Outcomes of Immunocompromised Children Hospitalized With Laboratory-Confirmed Influenza in the United States, 2011–2015
Collins JP, Campbell AP, Openo K, Farley MM, Cummings CN, Kirley PD, Herlihy R, Yousey-Hindes K, Monroe ML, Ladisky M, Lynfield R, Baumbach J, Spina N, Bennett N, Billing L, Thomas A, Schaffner W, Price A, Garg S, Anderson EJ. Clinical Features and Outcomes of Immunocompromised Children Hospitalized With Laboratory-Confirmed Influenza in the United States, 2011–2015. Journal Of The Pediatric Infectious Diseases Society 2018, 8: 539-549. PMID: 30358877, DOI: 10.1093/jpids/piy101.Peer-Reviewed Original ResearchConceptsSolid organ transplantationImmunocompromised childrenClinical featuresImmunosuppressive therapyIntensive careOrgan transplantationInfluenza Hospitalization Surveillance NetworkHuman immunodeficiency virus/Community-acquired influenzaEarly antiviral treatmentLonger hospitalization durationDuration of hospitalizationIntensive care admissionAntiviral useCare admissionHospital deathHospitalization durationInfluenza vaccinationAntiviral treatmentInfluenza seasonInfluenza severityPrimary outcomeImmunodeficiency syndromeMultivariable analysisImmunoglobulin deficiency
2017
Social determinants of influenza hospitalization in the United States
Chandrasekhar R, Sloan C, Mitchel E, Ndi D, Alden N, Thomas A, Bennett NM, Kirley PD, Hill M, Anderson EJ, Lynfield R, Yousey‐Hindes K, Bargsten M, Zansky SM, Lung K, Schroeder M, Monroe M, Eckel S, Markus TM, Cummings CN, Garg S, Schaffner W, Lindegren ML. Social determinants of influenza hospitalization in the United States. Influenza And Other Respiratory Viruses 2017, 11: 479-488. PMID: 28872776, PMCID: PMC5720587, DOI: 10.1111/irv.12483.Peer-Reviewed Original ResearchConceptsAdjusted odds ratioInfluenza hospitalizationsLaboratory-confirmed influenza-associated hospitalizationsHigher adjusted odds ratioPopulation-based surveillance systemInfluenza-associated hospitalizationsInfluenza seasonSubstantial morbidityVs 5Odds ratioHospitalizationHousehold crowdingSocial determinantsTractIndividual factorsMultilevel regression modelsSocioeconomic determinantsAfrican AmericansSurveillance systemRegression modelsUnited StatesHispanicsIndividual-level determinantsDeterminantsMorbidityImpact of pregnancy on observed sex disparities among adults hospitalized with laboratory‐confirmed influenza, FluSurv‐NET, 2010‐2012
Kline K, Hadler JL, Yousey‐Hindes K, Niccolai L, Kirley PD, Miller L, Anderson EJ, Monroe ML, Bohm SR, Lynfield R, Bargsten M, Zansky SM, Lung K, Thomas AR, Brady D, Schaffner W, Reed G, Garg S. Impact of pregnancy on observed sex disparities among adults hospitalized with laboratory‐confirmed influenza, FluSurv‐NET, 2010‐2012. Influenza And Other Respiratory Viruses 2017, 11: 404-411. PMID: 28703414, PMCID: PMC5596517, DOI: 10.1111/irv.12465.Peer-Reviewed Original ResearchConceptsIncidence rate ratiosInfluenza-associated hospitalizationsMale incidence rate ratiosPregnant womenLaboratory-confirmed influenza-associated hospitalizationsFemale incidence rate ratiosLaboratory-confirmed influenza casesLaboratory-confirmed influenzaLikelihood of vaccinationPopulation-based surveillanceNon-pregnant womenImpact of pregnancyNon-pregnant counterpartsCensus tract-level povertyObserved sex disparityGroup of womenTract-level povertyRace/ethnicityPregnant adult femalesFluSurv-NETHospitalized femalesInfluenza seasonAdult casesVaccination priorityVaccination ratesInfluenza Vaccination Modifies Disease Severity Among Community-dwelling Adults Hospitalized With Influenza
Arriola C, Garg S, Anderson EJ, Ryan PA, George A, Zansky SM, Bennett N, Reingold A, Bargsten M, Miller L, Yousey-Hindes K, Tatham L, Bohm SR, Lynfield R, Thomas A, Lindegren ML, Schaffner W, Fry AM, Chaves SS. Influenza Vaccination Modifies Disease Severity Among Community-dwelling Adults Hospitalized With Influenza. Clinical Infectious Diseases 2017, 65: 1289-1297. PMID: 28525597, PMCID: PMC5718038, DOI: 10.1093/cid/cix468.Peer-Reviewed Original ResearchConceptsLaboratory-confirmed influenzaInfluenza vaccinationDisease severityInfluenza seasonIntensive care unit admissionCare unit admissionMultivariable logistic regressionProbability of vaccinationCommunity-dwelling adultsHospital LOSICU LOSUnvaccinated patientsHospital deathICU admissionICU lengthUnit admissionAntiviral treatmentIllness onsetAdverse outcomesOutcome measuresVaccine virusAge strataVaccinationLogistic regressionPropensity score
2016
Utility of Keywords from Chest Radiograph Reports for Pneumonia Surveillance among Hospitalized Patients with Influenza: The CDC Influenza Hospitalization Surveillance Network, 2008–2009
Bramley AM, Chaves SS, Dawood FS, Doshi S, Reingold A, Miller L, Yousey-Hindes K, Farley MM, Ryan P, Lynfield R, Baumbach J, Zansky S, Bennett N, Thomas A, Schaffner W, Finelli L, Jain S. Utility of Keywords from Chest Radiograph Reports for Pneumonia Surveillance among Hospitalized Patients with Influenza: The CDC Influenza Hospitalization Surveillance Network, 2008–2009. Public Health Reports 2016, 131: 483-490. PMID: 27252568, PMCID: PMC4869084, DOI: 10.1177/003335491613100314.Peer-Reviewed Original ResearchConceptsLaboratory-confirmed influenza virus infectionInfluenza virus infectionPositive predictive valueChest radiograph reportsVirus infectionPercent agreementPneumonia surveillanceRadiograph reportsInfluenza Hospitalization Surveillance NetworkAdmission chest radiographsClinical Modification codesAbsence of pneumoniaDischarge summary dataComposite reference standardCohen's K statisticPublic health responsePublic health surveillanceU.S. study sitesStaff membersHospitalized patientsPleural effusionNinth RevisionPneumonia casesChest radiographsK statistic