2023
COVID-19–Associated Hospitalizations Among U.S. Adults Aged ≥65 Years — COVID-NET, 13 States, January–August 2023
Taylor C, Patel K, Patton M, Reingold A, Kawasaki B, Meek J, Openo K, Ryan P, Falkowski A, Bye E, Plymesser K, Spina N, Tesini B, Moran N, Sutton M, Talbot H, George A, Havers F, Team C, Team C, Kirley P, Armistead I, Yousey-Hindes K, Oosmanally N, Monroe M, Henderson J, D’Heilly P, Hancock E, Barney G, Bushey S, Billing L, Abdullah N, Schaffner W, Mendez E. COVID-19–Associated Hospitalizations Among U.S. Adults Aged ≥65 Years — COVID-NET, 13 States, January–August 2023. MMWR Morbidity And Mortality Weekly Report 2023, 72: 1089-1094. PMID: 37796744, PMCID: PMC10564325, DOI: 10.15585/mmwr.mm7240a3.Peer-Reviewed Original ResearchConceptsCOVID-19-associated hospitalizationCOVID-19-Associated Hospitalization Surveillance NetworkCOVID-19-associated hospitalization ratesHospitalization ratesAge groupsIntensive care unit admissionMultiple underlying conditionsSevere COVID-19 diseasePromote early treatmentPositive SARS-CoV-2 testSARS-CoV-2 infectionPrevent SARS-CoV-2 infectionYounger age groupsClinical characteristicsUnit admissionUnderlying conditionEarly treatmentSARS-CoV-2 testingIncreased riskSevere COVID-19-associated outcomesSevere outcomesCOVID-19 hospitalizationElevated riskCOVID-19 diseaseBivalent vaccine
2022
Comparison of Influenza and Coronavirus Disease 2019–Associated Hospitalizations Among Children Younger Than 18 Years Old in the United States: FluSurv-NET (October–April 2017–2021) and COVID-NET (October 2020–September 2021)
Delahoy MJ, Ujamaa D, Taylor CA, Cummings C, Anglin O, Holstein R, Milucky J, O’Halloran A, Patel K, Pham H, Whitaker M, Reingold A, Chai SJ, Alden NB, Kawasaki B, Meek J, Yousey-Hindes K, Anderson EJ, Openo KP, Weigel A, Teno K, Reeg L, Leegwater L, Lynfield R, McMahon M, Ropp S, Rudin D, Muse A, Spina N, Bennett NM, Popham K, Billing LM, Shiltz E, Sutton M, Thomas A, Schaffner W, Talbot HK, Crossland MT, McCaffrey K, Hall AJ, Burns E, McMorrow M, Reed C, Havers FP, Garg S. Comparison of Influenza and Coronavirus Disease 2019–Associated Hospitalizations Among Children Younger Than 18 Years Old in the United States: FluSurv-NET (October–April 2017–2021) and COVID-NET (October 2020–September 2021). Clinical Infectious Diseases 2022, 76: e450-e459. PMID: 35594564, PMCID: PMC9129156, DOI: 10.1093/cid/ciac388.Peer-Reviewed Original ResearchConceptsCOVID-19-associated hospitalizationInfluenza-associated hospitalization ratesHospitalization ratesIntensive care unit admissionPopulation-based surveillance systemCOVID-19COVID-19 pandemicCare unit admissionInfluenza-associated hospitalizationsComparison of influenzaSARS-CoV-2FluSurv-NETICU admissionUnit admissionHospital outcomesInfluenza seasonRespiratory virusesPediatric deathsPediatric hospitalizationsRespiratory illnessSevere outcomesOngoing COVID-19 pandemicAdolescents 12HospitalizationChildren 5Epidemiology, Clinical Characteristics, and Outcomes of Influenza-Associated Hospitalizations in US Children Over 9 Seasons Following the 2009 H1N1 Pandemic
Kamidani S, Garg S, Rolfes MA, Campbell AP, Cummings CN, Haston JC, Openo KP, Fawcett E, Chai SJ, Herlihy R, Yousey-Hindes K, Monroe ML, Kim S, Lynfield R, Smelser C, Muse A, Felsen CB, Billing L, Thomas A, Talbot HK, Schaffner W, Risk I, Anderson EJ. Epidemiology, Clinical Characteristics, and Outcomes of Influenza-Associated Hospitalizations in US Children Over 9 Seasons Following the 2009 H1N1 Pandemic. Clinical Infectious Diseases 2022, 75: 1930-1939. PMID: 35438769, DOI: 10.1093/cid/ciac296.Peer-Reviewed Original ResearchConceptsInfluenza Hospitalization Surveillance NetworkHospital mortality rateMechanical ventilationMortality rateIntensive care unit admissionRecent population-based dataCare unit admissionInfluenza vaccination ratesLaboratory-confirmed influenzaInfluenza-associated hospitalizationsMultivariable logistic regressionPopulation-based dataHospitalization incidence ratesMonths of ageUnit admissionAntiviral treatmentVaccination ratesRisk factorsIncidence rateHigher oddsUS childrenHospitalizationDisease controlLogistic regressionPneumonia
2021
Characteristics and Outcomes of Hospitalized Pregnant Women With Influenza, 2010 to 2019 : A Repeated Cross-Sectional Study.
Holstein R, Dawood FS, O'Halloran A, Cummings C, Ujamaa D, Daily Kirley P, Yousey-Hindes K, Fawcett E, Monroe ML, Kim S, Lynfield R, McMullen C, Muse A, Bennett NM, Billing LM, Sutton M, Thomas A, Talbot HK, Schaffner W, Risk I, Reed C, Garg S. Characteristics and Outcomes of Hospitalized Pregnant Women With Influenza, 2010 to 2019 : A Repeated Cross-Sectional Study. Annals Of Internal Medicine 2021, 175: 149-158. PMID: 34958603, DOI: 10.7326/m21-3668.Peer-Reviewed Original ResearchConceptsInfluenza-associated outcomesPregnant womenCross-sectional studyFetal outcomesHospital dischargeInfluenza seasonMechanical ventilationInfluenza Hospitalization Surveillance NetworkIntensive care unit admissionMedical chart abstractionRepeated cross-sectional studySevere maternal outcomesCare unit admissionLaboratory-confirmed influenzaReproductive-aged womenHospitalized pregnant womenInfluenza A H1N1Multivariable logistic regressionHigh-priority target groupUnit admissionHospital deathICU admissionMaternal outcomesChart abstractionClinical characteristicsRacial and Ethnic Disparities in Rates of COVID-19–Associated Hospitalization, Intensive Care Unit Admission, and In-Hospital Death in the United States From March 2020 to February 2021
Acosta AM, Garg S, Pham H, Whitaker M, Anglin O, O’Halloran A, Milucky J, Patel K, Taylor C, Wortham J, Chai SJ, Kirley PD, Alden NB, Kawasaki B, Meek J, Yousey-Hindes K, Anderson EJ, Openo KP, Weigel A, Monroe ML, Ryan P, Reeg L, Kohrman A, Lynfield R, Bye E, Torres S, Salazar-Sanchez Y, Muse A, Barney G, Bennett NM, Bushey S, Billing L, Shiltz E, Sutton M, Abdullah N, Talbot HK, Schaffner W, Ortega J, Price A, Fry AM, Hall A, Kim L, Havers FP. Racial and Ethnic Disparities in Rates of COVID-19–Associated Hospitalization, Intensive Care Unit Admission, and In-Hospital Death in the United States From March 2020 to February 2021. JAMA Network Open 2021, 4: e2130479. PMID: 34673962, PMCID: PMC8531997, DOI: 10.1001/jamanetworkopen.2021.30479.Peer-Reviewed Original ResearchConceptsCOVID-19-associated hospitalizationIntensive care unit admissionCare unit admissionSevere COVID-19Age-adjusted ratesICU admissionHospital deathUnit admissionWhite personsPacific Islander personsLaboratory-confirmed COVID-19-associated hospitalizationsAlaska NativesCOVID-19Positive SARS-CoV-2 testCOVID-19 Associated HospitalizationsEthnic disparitiesCOVID-19-Associated Hospitalization Surveillance NetworkSARS-CoV-2 testNon-Hispanic white personsIn-Hospital DeathRate ratioCross-sectional studyNon-Hispanic American IndianEthnic minority groupsNon-Hispanic blacksClinical Trends Among U.S. Adults Hospitalized With COVID-19, March to December 2020
Garg S, Patel K, Pham H, Whitaker M, O'Halloran A, Milucky J, Anglin O, Kirley PD, Reingold A, Kawasaki B, Herlihy R, Yousey-Hindes K, Maslar A, Anderson EJ, Openo KP, Weigel A, Teno K, Ryan PA, Monroe ML, Reeg L, Kim S, Como-Sabetti K, Bye E, Davis S, Eisenberg N, Muse A, Barney G, Bennett NM, Felsen CB, Billing L, Shiltz J, Sutton M, Abdullah N, Talbot HK, Schaffner W, Hill M, Chatelain R, Wortham J, Taylor C, Hall A, Fry AM, Kim L, Havers FP. Clinical Trends Among U.S. Adults Hospitalized With COVID-19, March to December 2020. Annals Of Internal Medicine 2021, 174: m21-1991. PMID: 34370517, PMCID: PMC8381761, DOI: 10.7326/m21-1991.Peer-Reviewed Original ResearchMeSH KeywordsAdenosine MonophosphateAdolescentAdrenal Cortex HormonesAdultAge DistributionAgedAlanineAntiviral AgentsCOVID-19Critical CareCross-Sectional StudiesFemaleHospitalizationHumansIntensive Care UnitsLength of StayMaleMiddle AgedPandemicsRespiration, ArtificialSARS-CoV-2United StatesVasoconstrictor AgentsYoung AdultConceptsICU admissionClinical trendsMechanical ventilationCOVID-19COVID-19-associated hospitalizationIntensive care unit admissionLaboratory-confirmed COVID-19U.S. adultsNon-Hispanic black personsCare unit admissionHospital death rateNoninvasive respiratory supportUse of remdesivirPercentage of interventionsCross-sectional studyCOVID-19 vaccineNon-Hispanic whitesSystemic corticosteroidsUnit admissionVasopressor useHospitalized adultsRespiratory supportCase patientsMedian ageSubstantial morbidityRates of Influenza-Associated Hospitalization, Intensive Care Unit Admission, and In-Hospital Death by Race and Ethnicity in the United States From 2009 to 2019
O’Halloran A, Holstein R, Cummings C, Kirley P, Alden NB, Yousey-Hindes K, Anderson EJ, Ryan P, Kim S, Lynfield R, McMullen C, Bennett NM, Spina N, Billing LM, Sutton M, Schaffner W, Talbot HK, Price A, Fry AM, Reed C, Garg S. Rates of Influenza-Associated Hospitalization, Intensive Care Unit Admission, and In-Hospital Death by Race and Ethnicity in the United States From 2009 to 2019. JAMA Network Open 2021, 4: e2121880. PMID: 34427679, PMCID: PMC8385599, DOI: 10.1001/jamanetworkopen.2021.21880.Peer-Reviewed Original ResearchConceptsInfluenza-associated hospitalizationsIntensive care unit admissionCare unit admissionCross-sectional studyHospitalization ratesPacific Islander childrenHospital deathICU admissionUnit admissionInfluenza seasonMAIN OUTCOMELaboratory-confirmed influenza-associated hospitalizationsAge groupsAge-adjusted hospitalization ratesHospital death rateICU admission rateInfluenza-associated diseaseInfluenza-associated outcomesIn-Hospital DeathSevere influenza diseaseHispanic childrenPopulation-based surveillanceWhite personsAlaska NativesAge-stratified rates
2020
Risk Factors for Intensive Care Unit Admission and In-hospital Mortality Among Hospitalized Adults Identified through the US Coronavirus Disease 2019 (COVID-19)-Associated Hospitalization Surveillance Network (COVID-NET)
Kim L, Garg S, O’Halloran A, Whitaker M, Pham H, Anderson EJ, Armistead I, Bennett NM, Billing L, Como-Sabetti K, Hill M, Kim S, Monroe ML, Muse A, Reingold AL, Schaffner W, Sutton M, Talbot HK, Torres SM, Yousey-Hindes K, Holstein R, Cummings C, Brammer L, Hall AJ, Fry AM, Langley GE. Risk Factors for Intensive Care Unit Admission and In-hospital Mortality Among Hospitalized Adults Identified through the US Coronavirus Disease 2019 (COVID-19)-Associated Hospitalization Surveillance Network (COVID-NET). Clinical Infectious Diseases 2020, 72: e206-e214. PMID: 32674114, PMCID: PMC7454425, DOI: 10.1093/cid/ciaa1012.Peer-Reviewed Original ResearchConceptsIntensive care unit admissionCare unit admissionHospital mortalityICU admissionUnit admissionMale sexRisk factorsAge 50Independent factorsCOVID-19-related complicationsLaboratory-confirmed COVID-19Surveillance networkCoronavirus disease 2019 (COVID-19) casesInvasive mechanical ventilationIn-Hospital MortalityChronic lung diseaseAcute care hospitalsCoronavirus disease 2019COVID-19Rigorous hand hygieneRenal diseaseMechanical ventilationMultivariable analysisLung diseaseSevere outcomes
2017
Influenza Vaccination Modifies Disease Severity Among Community-dwelling Adults Hospitalized With Influenza
Arriola C, Garg S, Anderson EJ, Ryan PA, George A, Zansky SM, Bennett N, Reingold A, Bargsten M, Miller L, Yousey-Hindes K, Tatham L, Bohm SR, Lynfield R, Thomas A, Lindegren ML, Schaffner W, Fry AM, Chaves SS. Influenza Vaccination Modifies Disease Severity Among Community-dwelling Adults Hospitalized With Influenza. Clinical Infectious Diseases 2017, 65: 1289-1297. PMID: 28525597, PMCID: PMC5718038, DOI: 10.1093/cid/cix468.Peer-Reviewed Original ResearchConceptsLaboratory-confirmed influenzaInfluenza vaccinationDisease severityInfluenza seasonIntensive care unit admissionCare unit admissionMultivariable logistic regressionProbability of vaccinationCommunity-dwelling adultsHospital LOSICU LOSUnvaccinated patientsHospital deathICU admissionICU lengthUnit admissionAntiviral treatmentIllness onsetAdverse outcomesOutcome measuresVaccine virusAge strataVaccinationLogistic regressionPropensity score