2024
Acute Cardiac Events in Hospitalized Older Adults With Respiratory Syncytial Virus Infection
Woodruff R, Melgar M, Pham H, Sperling L, Loustalot F, Kirley P, Austin E, Yousey-Hindes K, Openo K, Ryan P, Brown C, Lynfield R, Davis S, Barney G, Tesini B, Sutton M, Talbot H, Zahid H, Kim L, Havers F, Rowlands J, Spina N, Engesser K, Salazar-Sanchez Y, George A, Staten H, Bleecker M, Leegwater L, Tellez Nunez V, Falkowski A, Felsen C, Licherdell E, St George K, Pacheco F, Desiato J, Labozzo N, Zmek E, Alden N, Strayhorn N, Fawcett E, Surell C, Como-Sabetti K, Mumm E, Bilski K, Markus T, Ndi D, Billings K. Acute Cardiac Events in Hospitalized Older Adults With Respiratory Syncytial Virus Infection. JAMA Internal Medicine 2024, 184: 602-611. PMID: 38619857, PMCID: PMC11019447, DOI: 10.1001/jamainternmed.2024.0212.Peer-Reviewed Original ResearchRespiratory syncytial virus infectionRespiratory syncytial virusRespiratory syncytial virus seasonAcute cardiac eventsCardiac eventsWeighted estimated prevalenceIn-hospital deathAdjusted risk ratiosIntensive care unitClassification of DiseasesCross-sectional studyHospitalized adultsCardiac complicationsRSV infectionRSV diseaseLaboratory-confirmed RSV infectionOlder adultsCases of RSV infectionReceipt of invasive mechanical ventilationCardiovascular diseaseIntensive care unit admissionSevere outcomesEstimated prevalenceAcute heart failurePotential cardiac complications
2023
COVID-19–Associated Hospitalizations Among U.S. Adults Aged ≥65 Years — COVID-NET, 13 States, January–August 2023
Taylor C, Patel K, Patton M, Reingold A, Kawasaki B, Meek J, Openo K, Ryan P, Falkowski A, Bye E, Plymesser K, Spina N, Tesini B, Moran N, Sutton M, Talbot H, George A, Havers F, Team C, Team C, Kirley P, Armistead I, Yousey-Hindes K, Oosmanally N, Monroe M, Henderson J, D’Heilly P, Hancock E, Barney G, Bushey S, Billing L, Abdullah N, Schaffner W, Mendez E. COVID-19–Associated Hospitalizations Among U.S. Adults Aged ≥65 Years — COVID-NET, 13 States, January–August 2023. MMWR Morbidity And Mortality Weekly Report 2023, 72: 1089-1094. PMID: 37796744, PMCID: PMC10564325, DOI: 10.15585/mmwr.mm7240a3.Peer-Reviewed Original ResearchConceptsCOVID-19-associated hospitalizationCOVID-19-Associated Hospitalization Surveillance NetworkCOVID-19-associated hospitalization ratesHospitalization ratesAge groupsIntensive care unit admissionMultiple underlying conditionsSevere COVID-19 diseasePromote early treatmentPositive SARS-CoV-2 testSARS-CoV-2 infectionPrevent SARS-CoV-2 infectionYounger age groupsClinical characteristicsUnit admissionUnderlying conditionEarly treatmentSARS-CoV-2 testingIncreased riskSevere COVID-19-associated outcomesSevere outcomesCOVID-19 hospitalizationElevated riskCOVID-19 diseaseBivalent vaccineSeverity of influenza-associated hospitalisations by influenza virus type and subtype in the USA, 2010–19: a repeated cross-sectional study
Sumner K, Masalovich S, O’Halloran A, Holstein R, Reingold A, Kirley P, Alden N, Herlihy R, Meek J, Yousey-Hindes K, Anderson E, Openo K, Monroe M, Leegwater L, Henderson J, Lynfield R, McMahon M, McMullen C, Angeles K, Spina N, Engesser K, Bennett N, Felsen C, Lung K, Shiltz E, Thomas A, Talbot H, Schaffner W, Swain A, George A, Rolfes M, Reed C, Garg S. Severity of influenza-associated hospitalisations by influenza virus type and subtype in the USA, 2010–19: a repeated cross-sectional study. The Lancet Microbe 2023, 4: e903-e912. PMID: 37769676, PMCID: PMC10872935, DOI: 10.1016/s2666-5247(23)00187-8.Peer-Reviewed Original ResearchConceptsInfluenza virus typeInfluenza-associated hospitalisationsInfluenza seasonInfluenza B virusICU admissionMechanical ventilationSevere outcomesOdds ratioVirus typeFluSurv-NETECMO useInfluenza vaccineB virusVirus infectionLaboratory-confirmed influenza virus infectionInfluenza Hospitalization Surveillance NetworkInfluenza B virus infectionPopulation-based surveillance systemComplete chart reviewEarly antiviral treatmentHospital-onset casesInfluenza-associated outcomesRepeated cross-sectional studyInfluenza vaccination statusB virus infection
2022
Drug use and severe outcomes among adults hospitalized with influenza, 2016–2019
Parisi C, Yousey‐Hindes K, Holstein R, O'Halloran A, Kirley P, Alden N, Anderson E, Kim S, McMahon M, Khanlian S, Spina N, Gaitan M, Shiltz E, Thomas A, Schaffner W, Talbot K, Crossland M, Cook R, Garg S, Meek J, Hadler J. Drug use and severe outcomes among adults hospitalized with influenza, 2016–2019. Influenza And Other Respiratory Viruses 2022, 17: e13052. PMID: 36300969, PMCID: PMC9835414, DOI: 10.1111/irv.13052.Peer-Reviewed Original ResearchConceptsSevere outcomesDrug useICU admissionMechanical ventilationInfluenza Hospitalization Surveillance NetworkInfluenza-associated outcomesSevere influenza outcomesPersistent public health problemChronic liver diseaseChronic lung diseasePublic health problemNon-Hispanic blacksLogistic regression modelsHispanics/LatinosSmoke tobaccoInfluenza vaccinationOpioid useImmunosuppressive conditionsInfluenza seasonSevere morbidityInfluenza infectionInfluenza outcomesLiver diseaseLung diseaseChronic conditionsComparison of Influenza and Coronavirus Disease 2019–Associated Hospitalizations Among Children Younger Than 18 Years Old in the United States: FluSurv-NET (October–April 2017–2021) and COVID-NET (October 2020–September 2021)
Delahoy MJ, Ujamaa D, Taylor CA, Cummings C, Anglin O, Holstein R, Milucky J, O’Halloran A, Patel K, Pham H, Whitaker M, Reingold A, Chai SJ, Alden NB, Kawasaki B, Meek J, Yousey-Hindes K, Anderson EJ, Openo KP, Weigel A, Teno K, Reeg L, Leegwater L, Lynfield R, McMahon M, Ropp S, Rudin D, Muse A, Spina N, Bennett NM, Popham K, Billing LM, Shiltz E, Sutton M, Thomas A, Schaffner W, Talbot HK, Crossland MT, McCaffrey K, Hall AJ, Burns E, McMorrow M, Reed C, Havers FP, Garg S. Comparison of Influenza and Coronavirus Disease 2019–Associated Hospitalizations Among Children Younger Than 18 Years Old in the United States: FluSurv-NET (October–April 2017–2021) and COVID-NET (October 2020–September 2021). Clinical Infectious Diseases 2022, 76: e450-e459. PMID: 35594564, PMCID: PMC9129156, DOI: 10.1093/cid/ciac388.Peer-Reviewed Original ResearchConceptsCOVID-19-associated hospitalizationInfluenza-associated hospitalization ratesHospitalization ratesIntensive care unit admissionPopulation-based surveillance systemCOVID-19COVID-19 pandemicCare unit admissionInfluenza-associated hospitalizationsComparison of influenzaSARS-CoV-2FluSurv-NETICU admissionUnit admissionHospital outcomesInfluenza seasonRespiratory virusesPediatric deathsPediatric hospitalizationsRespiratory illnessSevere outcomesOngoing COVID-19 pandemicAdolescents 12HospitalizationChildren 5
2020
Risk Factors for Intensive Care Unit Admission and In-hospital Mortality Among Hospitalized Adults Identified through the US Coronavirus Disease 2019 (COVID-19)-Associated Hospitalization Surveillance Network (COVID-NET)
Kim L, Garg S, O’Halloran A, Whitaker M, Pham H, Anderson EJ, Armistead I, Bennett NM, Billing L, Como-Sabetti K, Hill M, Kim S, Monroe ML, Muse A, Reingold AL, Schaffner W, Sutton M, Talbot HK, Torres SM, Yousey-Hindes K, Holstein R, Cummings C, Brammer L, Hall AJ, Fry AM, Langley GE. Risk Factors for Intensive Care Unit Admission and In-hospital Mortality Among Hospitalized Adults Identified through the US Coronavirus Disease 2019 (COVID-19)-Associated Hospitalization Surveillance Network (COVID-NET). Clinical Infectious Diseases 2020, 72: e206-e214. PMID: 32674114, PMCID: PMC7454425, DOI: 10.1093/cid/ciaa1012.Peer-Reviewed Original ResearchConceptsIntensive care unit admissionCare unit admissionHospital mortalityICU admissionUnit admissionMale sexRisk factorsAge 50Independent factorsCOVID-19-related complicationsLaboratory-confirmed COVID-19Surveillance networkCoronavirus disease 2019 (COVID-19) casesInvasive mechanical ventilationIn-Hospital MortalityChronic lung diseaseAcute care hospitalsCoronavirus disease 2019COVID-19Rigorous hand hygieneRenal diseaseMechanical ventilationMultivariable analysisLung diseaseSevere outcomes
2018
2494. Influenza B Hospitalizations Are Associated With Mortality in Children, FluSurv-NET, 2011–2017
Garg S, O’Halloran A, Cummings C, Chai S, Alden N, Yousey-Hindes K, Anderson E, Ryan P, Collins J, Smelser C, Blog D, Felsen C, Billing L, Thomas A, Talbot H, Spencer M, Lynfield R, Reed C. 2494. Influenza B Hospitalizations Are Associated With Mortality in Children, FluSurv-NET, 2011–2017. Open Forum Infectious Diseases 2018, 5: s748-s749. PMCID: PMC6255344, DOI: 10.1093/ofid/ofy210.2146.Peer-Reviewed Original ResearchHospital mortalityUnivariate analysisVirus infectionInfluenza Hospitalization Surveillance NetworkInfluenza B virus infectionLaboratory-confirmed influenzaB virus infectionInfluenza-associated hospitalizationsMultivariable logistic regressionInfluenza B virusNon-Hispanic whitesCharacteristics of childrenClinical courseMedian ageMedical chartsMechanical ventilationIllness onsetIntensive careUnadjusted oddsHospitalized childrenB virusIndependent associationSevere outcomesNeurologic diseaseInfluenza type
2013
Heavy alcohol use as a risk factor for severe outcomes among adults hospitalized with laboratory-confirmed influenza, 2005–2012
Greenbaum A, Chaves S, Perez A, Aragon D, Bandyopadhyay A, Bennett N, Fowler B, Hancock E, Lynfield R, McDonald-Hamm C, Reingold A, Ryan P, Schaffner W, Sharangpani R, Spencer M, Thomas A, Yousey-Hindes K, Zansky S, Finelli L. Heavy alcohol use as a risk factor for severe outcomes among adults hospitalized with laboratory-confirmed influenza, 2005–2012. Infection 2013, 42: 165-170. PMID: 24243481, DOI: 10.1007/s15010-013-0534-8.Peer-Reviewed Original Research