2023
Effect of Alteplase on Ischemic Stroke Mortality Is Dependent on Stroke Severity
de Havenon A, Abbasi M, Yaghi S, Delic A, Bangad A, Johnston K, Tirschwell D, Sheth K. Effect of Alteplase on Ischemic Stroke Mortality Is Dependent on Stroke Severity. Annals Of Neurology 2023, 93: 1106-1116. PMID: 36852919, DOI: 10.1002/ana.26621.Peer-Reviewed Original ResearchConceptsIV-tPAHigher NIHSSIschemic strokeAtrial fibrillationNational Inpatient Sample (NIS) 2016Non-Hispanic white raceOlder ageBaseline National InstitutesDEFUSE-3 trialsHealth Stroke ScalePost-stroke mortalityIschemic stroke mortalityEffect of alteplaseRisk of mortalityLogistic regression modelsAnn NeurolFAST-MAGIMS IIISevere ISHospital mortalityIntravenous alteplaseSevere strokeStroke ScaleStroke severityFunctional outcome
2021
Author Response: Cause of Death in Spontaneous Intracerebral Hemorrhage Survivors: Multistate Longitudinal Study
Kuohn L, Sheth K. Author Response: Cause of Death in Spontaneous Intracerebral Hemorrhage Survivors: Multistate Longitudinal Study. Neurology 2021, 97: 149-149. DOI: 10.1212/wnl.0000000000012283.Peer-Reviewed Original ResearchIntracerebral hemorrhage survivorsSpontaneous intracerebral hemorrhage survivorsAdjusted multinomial logistic regression modelIndependent risk factorInfection-related mortalityBurden of disabilityInfection-related deathsInfection-related morbidityUrinary tract infectionOdds of deathLong-term outcomesCause of deathLogistic regression modelsDeath overallICH survivorsAspiration pneumoniaMultinomial logistic regression modelsTract infectionsChronic hospitalizationRisk factorsDiabetesPotential associationClostridium difficileInfectionOlder age