2024
Cerebral Amyloid Angiopathy and Risk of Isolated Nontraumatic Subdural Hemorrhage
Rivier C, Kamel H, Sheth K, Iadecola C, Gupta A, de Leon M, Ross E, Falcone G, Murthy S. Cerebral Amyloid Angiopathy and Risk of Isolated Nontraumatic Subdural Hemorrhage. JAMA Neurology 2024, 81: 163-169. PMID: 38147345, PMCID: PMC10751656, DOI: 10.1001/jamaneurol.2023.4918.Peer-Reviewed Original ResearchCerebral amyloid angiopathyMultivariable logistic regression analysisSubdural hemorrhageLogistic regression analysisIntracerebral hemorrhageIntracranial hemorrhageUK Biobank cohortAmyloid angiopathyMean ageUS cohortRisk factorsHigher oddsDiagnosis of CAAPopulation-based cohort studyBiobank cohortClinical Modification diagnosis codesCAA-related intracerebral hemorrhageCox proportional hazards modelRegression analysisAntithrombotic medication useIndependent risk factorCox regression analysisMultivariable logistic regressionNovel risk factorsSpontaneous intracerebral hemorrhageImpaired mobility and MRI markers of vascular brain injury: Atherosclerosis Risk in Communities and UK Biobank studies
Sharma R, de Havenon A, Rivier C, Payabvash S, Forman R, Krumholz H, Falcone G, Sheth K, Kernan W. Impaired mobility and MRI markers of vascular brain injury: Atherosclerosis Risk in Communities and UK Biobank studies. BMJ Neurology Open 2024, 6: e000501. PMID: 38288313, PMCID: PMC10823923, DOI: 10.1136/bmjno-2023-000501.Peer-Reviewed Original ResearchVascular brain injurySlow walkingAtherosclerosis RiskMobility impairmentsAssociated with mobility impairmentImpaired mobilityUK Biobank (UKBStroke-free cohortMarkers of vascular brain injuryAdjusted multivariate logistic regression analysisGait dataMultivariate logistic regression analysisCommunity-dwellingLogistic regression analysisBrain injuryARICUKBInclusion criteriaStudy cohortWalkingClinical strokeRegression analysisImpaired outcomeMRI markersStudy background
2023
Antithrombotic and Statin Prescription After Intracerebral Hemorrhage in the Get With The Guidelines-Stroke Registry
Murthy S, Zhang C, Shah S, Schwamm L, Fonarow G, Smith E, Bhatt D, Ziai W, Kamel H, Sheth K. Antithrombotic and Statin Prescription After Intracerebral Hemorrhage in the Get With The Guidelines-Stroke Registry. Stroke 2023, 54: 2972-2980. PMID: 37942641, PMCID: PMC10842167, DOI: 10.1161/strokeaha.123.043194.Peer-Reviewed Original ResearchConceptsIschemic vascular diseaseProportion of patientsGuidelines-Stroke registryLipid-lowering therapyIntracerebral hemorrhageVascular diseaseStatin therapyAnticoagulation therapyCardiovascular eventsAtrial fibrillationFuture major cardiovascular eventsLower admission National InstitutesPrevious lipid-lowering therapyAdmission National InstitutesFavorable discharge outcomeIschemic cardiovascular eventsHealth Stroke ScaleMajor cardiovascular eventsLipid-lowering medicationsCross-sectional studyMultiple logistic regressionLogistic regression analysisAntiplatelet medicationsAntiplatelet therapyStatin medication