2024
Impact of sleep quality and physical activity on blood pressure variability
de Havenon A, Falcone G, Rivier C, Littig L, Petersen N, de Villele P, Prabhakaran S, Kimberly W, Mistry E, Sheth K. Impact of sleep quality and physical activity on blood pressure variability. PLOS ONE 2024, 19: e0301631. PMID: 38625967, PMCID: PMC11020843, DOI: 10.1371/journal.pone.0301631.Peer-Reviewed Original ResearchConceptsSleep qualityPhysical activityOdds ratioCohort of community-dwelling adultsCommunity-dwelling adultsExcess relative riskBlood pressure variabilityExamined sleep qualityPoor sleep qualitySystolic blood pressure standard deviationSleep interruptionBody mass indexPhysical inactivityPrimary study outcomeStep countsImpact of sleep qualityLowest tertileRelative riskHigh blood pressure variabilityHome measurement devicesActivity levelsExposure statusPoor sleepMass indexStudy outcomes
2023
Association of Body Mass Index and Waist Circumference With Imaging Metrics of Brain Integrity and Functional Connectivity in Children Aged 9 to 10 Years in the US, 2016-2018
Kaltenhauser S, Weber C, Lin H, Mozayan A, Malhotra A, Constable R, Acosta J, Falcone G, Taylor S, Ment L, Sheth K, Payabvash S. Association of Body Mass Index and Waist Circumference With Imaging Metrics of Brain Integrity and Functional Connectivity in Children Aged 9 to 10 Years in the US, 2016-2018. JAMA Network Open 2023, 6: e2314193. PMID: 37200030, PMCID: PMC10196880, DOI: 10.1001/jamanetworkopen.2023.14193.Peer-Reviewed Original ResearchConceptsBody mass indexHigher body mass indexWaist circumferenceBMI z-scoreCross-sectional studyBrain healthCross-sectional analysisFunctional connectivityMass indexMean ageInterval developmentCorpus callosumAssociation of BMIHigher baseline body mass indexBaseline cross-sectional analysisBaseline body mass indexBrain integrityResting-state functional connectivityLongitudinal analysisFuture treatment trialsABCD studyLower microstructural integrityCognitive Development StudyAdolescent Brain Cognitive Development (ABCD) studyCardiovascular implications
2019
Genetic and lifestyle risk factors for MRI-defined brain infarcts in a population-based setting
Chauhan G, Adams H, Satizabal C, Bis J, Teumer A, Sargurupremraj M, Hofer E, Trompet S, Hilal S, Smith A, Jian X, Malik R, Traylor M, Pulit S, Amouyel P, Mazoyer B, Zhu Y, Kaffashian S, Schilling S, Beecham G, Montine T, Schellenberg G, Kjartansson O, Guðnason V, Knopman D, Griswold M, Windham B, Gottesman R, Mosley T, Schmidt R, Saba Y, Schmidt H, Takeuchi F, Yamaguchi S, Nabika T, Kato N, Rajan K, Aggarwal N, De Jager P, Evans D, Psaty B, Rotter J, Rice K, Lopez O, Liao J, Chen C, Cheng C, Wong T, Ikram M, van der Lee S, Amin N, Chouraki V, DeStefano A, Aparicio H, Romero J, Maillard P, DeCarli C, Wardlaw J, del C. Valdés Hernández M, Luciano M, Liewald D, Deary I, Starr J, Bastin M, Maniega S, Slagboom P, Beekman M, Deelen J, Uh H, Lemmens R, Brodaty H, Wright M, Ames D, Boncoraglio G, Hopewell J, Beecham A, Blanton S, Wright C, Sacco R, Wen W, Thalamuthu A, Armstrong N, Chong E, Schofield P, Kwok J, van der Grond J, Stott D, Ford I, Jukema J, Vernooij M, Hofman A, Uitterlinden A, van der Lugt A, Wittfeld K, Grabe H, Hosten N, von Sarnowski B, Völker U, Levi C, Jimenez-Conde J, Sharma P, Sudlow C, Rosand J, Woo D, Cole J, Meschia J, Slowik A, Thijs V, Lindgren A, Melander O, Grewal R, Rundek T, Rexrode K, Rothwell P, Arnett D, Jern C, Johnson J, Benavente O, Wasssertheil-Smoller S, Lee J, Wong Q, Mitchell B, Rich S, McArdle P, Geerlings M, van der Graaf Y, de Bakker P, Asselbergs F, Srikanth V, Thomson R, McWhirter R, Moran C, Callisaya M, Phan T, Rutten-Jacobs L, Bevan S, Tzourio C, Mather K, Sachdev P, van Duijn C, Worrall B, Dichgans M, Kittner S, Markus H, Ikram M, Fornage M, Launer L, Seshadri S, Longstreth W, Debette S, the International Stroke Genetics Consortium M, Almgren P, Anderson C, Arnett D, Attia J, Ay H, Benavente O, Bevan S, Brown R, Bustamante M, Cheng Y, Cole J, Cotlarciuc I, Cruchaga C, de Bakker P, Delavaran H, Dichgans M, Engström G, Fornage M, Grewal R, Heitsch L, Holliday E, Ibanez L, Ilinca A, Irvin M, Jackson R, Jern C, Jimenez-Conde J, Johnson J, Jood K, Kissela B, Kittner S, Kleindorfer D, Labovitz D, Laurie C, Lee J, Lemmens R, Levi C, Li L, Lindgren A, Maguire J, Markus H, McArdle P, Melander O, Meschia J, Mitchell B, Müller-Nurasyid M, Norrving B, Peddareddygari L, Pera J, Pulit S, Rexrode K, Ribasés M, Roquer J, Rost N, Rothwell P, Rundek T, Sacco R, Schmidt R, Sharma P, Slowik A, Soriano-Tárraga C, Stanne T, Stauch K, Stine O, Sudlow C, Thijs V, Wasssertheil-Smoller S, Weir D, Williams S, Wong Q, Woo D, Worrall B, Xu H, Seshadri S, Hyacinth H, Marini S, Nyquist P, Lewis C, Hansen B, Norrving B, Rosand J, Biffi A, Kourkoulis C, Anderson C, Giese A, Sacco R, Sharma P, Chung J, Kim G, Lubitz S, Bourcier R, Howson J, Granata A, Drazyk A, Markus H, Wardlaw J, Mitchell B, Cole J, Hopewell J, Walters R, Turnbull I, Worrall B, Bis J, Reiner A, Dhar R, Heitsch L, Lee J, Prasad K, Sarnowski C, Aparicio H, Yang Q, Chasman D, Rexrode K, Phuah C, Liu G, Elkind M, Lange L, Rost N, James M, Stewart J, Vojinovic D, Thijs V, Parati E, Boncoraglio G, Zand R, Bijlenga P, Selim M, Grond-Ginsbach C, Strbian D, Tomppo L, Sallinen H, Pfeiffer D, Torres N, Barboza M, Laarman M, Carriero R, Holliday E, Jimenez-Conde J, Soriano C, Gill D, Debette S, Mishra A, Wu J, Ko T, Bione S, Jood K, Tatlisumak T, Holmegaard L, Yue S, bersano A, Pera J, Slowik A, Levi C, Schlicht K, Lemmens R, Ninomiya T, Oberstein S, Lee T, Malik R, Dichgans M, Lindgren A, Wasselius J, Drake M, Melander O, Stenman M, Ilinca A, Crawford K, Lena U, Mateen F, Ay H, Wu O, Schirmer M, Cramer S, Golland P, Brown R, Meschia J, Ross O, Pare G, Chong M, Rundek T, Gwinn K, Chen C, Koenig J, Giralt E, Saleheen D, de Leeuw F, Klijn K, Kamatani Y, Kubo M, Okada Y, Pedersen A, Olsson M, Martín J, Xu H, Tan E, Frid P, Lee C, Tregouet D, Leung T, Choy R, Jern C, Loo K, Rinkel G, Franca P, Cendes I, Carrera C, Fernandez-Cadenas I, Montaner J, Kim H, Owolabi M, Sofat R, Bakker M, Ruigrok Y, Hauer A, Pulit S, van der Laan S, Irvin R, Sargurupremraj M, Pezzini A, Abd-Allah F, Liebeskind D, Traylor M, Tan R, Danesh J, Rutten-Jacobs L, Donatti A, Avelar W, Broderick J, Woo D, Sudlow C, Rannikmae K, McDonough C, van Agtmael T, Walters M, Söderholm M, Lorentzen E, Olsson S, Stanne T, Olsson M, Akinyemi R, Cotlatciuc I, McArdle P, Dave T, Kittner S, Attia J, Faber J, Millwood I, Márquez E, Mancuso M, Vibo R, Korv J, Maguire J, Fornage M, Majersik J, DeHavenon A, Alexander M, Sale M, Southerland A, Owens D, Psaty B, Longstreth W, Wolfe S, Langefeld C, Cruchaga C, Konrad J, Sheth K, Falcone G, Donahue K, Simpkins A, Byorn T, Chan B, Clatworthy P, Florez J, Harshfield E, Hozawa A, Hsu C, Hu C, Ibanez L, Ihara M, Lange M, Lee S, Lee I, Musolino P, Nakatomi H, Park K, Rich S, Riley C, Sung J, Suzuki H, Vo K, Washida K, Ibenez L, Slowik A, Hofman A, Algra A, Reiner A, Doney A, Gschwendtner A, Ilinca A, Giese A, Lindgren A, Vicente A, Norrving B, Nordestgaard B, Mitchell B, Worrall B, Psaty B, Carty C, Sudlow C, Anderson C, Levi C, Satizabal C, Palmer C, Gamble D, Woo D, Saleheen D, Ringelstein E, Valdimarsson E, Holliday E, Davies G, Chauhan G, Pasterkamp G, Boncoraglio G, Kuhlenbäumer G, Thorleifsson G, Falcone G, Pare G, Schmidt H, Delavaran H, Markus H, Aparicio H, Deary I, Cotlarciuc I, Fernandez-Cadenas I, Meschia J, Hopewell J, Liu J, Montaner J, Pera J, Cole J, Attia J, Rosand J, Ferro J, Bis J, Furie K, Stefansson K, Berger K, Kostulas K, Rannikmae K, Ikram M, Benn M, Dichgans M, Farrall M, Pandolfo M, Traylor M, Walters M, Sale M, Nalls M, Fornage M, van Zuydam N, Sharma P, Abrantes P, de Bakker P, Higgins P, Lichtner P, Rothwell P, Amouyel P, Yang Q, Malik R, Schmidt R, Clarke R, Lemmens R, van der Laan S, Pulit S, Abboud S, Oliveira S, Gretarsdottir S, Debette S, Williams S, Bevan S, Kittner S, Seshadri S, Mosley T, Battey T, Tatlisumak T, Thorsteinsdottir U, Thijs V, Longstreth W, Zhao W, Chen W, Cheng Y, Albert M, Albin R, Apostolova L, Arnold S, Asthana S, Atwood C, Baldwin C, Barmada M, Barnes L, Barral S, Beach T, Becker J, Beecham G, Beekly D, Bennett D, Bigio E, Bird T, Blacker D, Boeve B, Boxer A, Burke J, Burns J, Buxbaum J, Byrd G, Cai G, Cairns N, Cantwell L, Cao C, Carlsson C, Carney R, Carrasquillo M, Carroll S, Chui H, Clark D, Cribbs D, Crocco E, Cruchaga C, De Jager P, DeCarli C, Demirci F, Dick M, Dickson D, Duara R, Ertekin-Taner N, Evans D, Faber K, Fallin M, Fallon K, Fardo D, Farlow M, Farrer L, Ferris S, Foroud T, Frosch M, Galasko D, Gearing M, Geschwind D, Ghetti B, Gilbert J, Go R, Goate A, Graff-Radford N, Green R, Griffith P, Growdon J, Haines J, Hakonarson H, Hamilton R, Hamilton-Nelson K, Haroutunian V, Harrell L, Honig L, Huebinger R, Hulette C, Hyman B, Jicha G, Jin L, Jun G, Kamboh M, Karydas A, Kauwe J, Kaye J, Kim R, Kowall N, Kramer J, Kukull W, Kunkle B, LaFerla F, Lah J, Lang-Walker R, Larson E, Leverenz J, Levey A, Li G, Lieberman A, Logue M, Lopez O, Lunetta K, Lyketsos C, Mack W, Manly J, Marson D, Martin E, Martiniuk F, Mash D, Masliah E, Mayeux R, McKee A, Mesulam M, Miller B, Miller C, Miller J, Montine T, Morris J, Murrell J, Naj A, Obisesan T, Olichney J, Pankratz V, Parisi J, Partch A, Paulson H, Pericak-Vance M, Perry W, Peskind E, Petersen R, Pierce A, Poon W, Potter H, Quinn J, Raj A, Raj T, Raskind M, Reiman E, Reisberg B, Reitz C, Ringman J, Roberson E, Rosen H, Rosenberg R, Sager M, Sano M, Saykin A, Schellenberg G, Schneider J, Schneider L, Seeley W, Smith A, Sonnen J, Spina S, Stern R, Swerdlow R, Tanzi R, Thornton-Wells T, Trojanowski J, Troncoso J, Tsuang D, Valladares O, Van Deerlin V, Van Eldik L, Vardarajan B, Vinters H, Vonsattel J, Wang L, Weintraub S, Welsh-Bohmer K, Williamson J, Wingo T, Wishnek S, Woltjer R, Wright C, Younkin S, Yu C, Yu L, Chauhan G, Chu A, Fornage M, Bis J, Havulinna A, Sargurupremraj M, Smith A, Adams H, Choi S, Trompet S, Garcia M, Manichaikul A, Teumer A, Gustafsson S, Bartz T, Bellenguez C, Vidal J, Jian X, Kjartansson O, Wiggins K, Satizabal C, Xue F, Ripatti S, Liu Y, Deelen J, Hoed M, Heckbert S, Rice K, Smith N, Wong Q, Aparicio H, Buring J, Ridker P, Berr C, Dartigues J, Hamsten A, Magnusson P, Pedersen N, Lannfelt L, Lind L, Lindgren C, Morris A, Hofman A, Koudstaal P, Portegies M, Uitterlinden A, de Craen A, Ford I, Jukema J, Stott D, Allen N, Sale M, Johnson A, Bennett D, De Jager P, White C, Grabe H, Markus M, Lopez O, Rotter J, Nalls M, Gottesman R, Griswold M, Knopman D, Windham B, Beiser A, Vartiainen E, French C, Kurth T, Psaty B, Harris T, Rich S, deStefano A, Schmidt C, Salomaa V, Mosley T, Ingelsson E, van Duijn C, Tzourio C, Launer L, Ikram M, Chasman D, Longstreth W, Seshadri S, Debette S, Verhaaren B, Debette S, Bis J, Smith J, Ikram M, Adams H, Beecham A, Rajan K, Lopez L, Barral S, van Buchem M, van der Grond J, Smith A, Hegenscheid K, Aggarwal N, de Andrade M, Atkinson E, Beekman M, Beiser A, Blanton S, Boerwinkle E, Brickman A, Bryan R, Chauhan G, Chen C, Chouraki V, de Craen A, Crivello F, Deary I, Deelen J, De Jager P, Dufouil C, Elkind M, Evans D, Freudenberger P, Gottesman R, Guðnason V, Habes M, Heckbert S, Heiss G, Hilal S, Hofer E, Hofman A, Ibrahim-Verbaas C, Knopman D, Lewis C, Liao J, Liewald D, Luciano M, van der Lugt A, Martinez O, Mayeux R, Mazoyer B, Nalls M, Nauck M, Niessen W, Oostra B, Psaty B, Rice K, Rotter J, von Sarnowski B, Schmidt H, Schreiner P, Schuur M, Sidney S, Sigurdsson S, Slagboom P, Stott D, van Swieten J, Teumer A, Töglhofer A, Traylor M, Trompet S, Turner S, Tzourio C, Uh H, Uitterlinden A, Vernooij M, Wang J, Wong T, Wardlaw J, Windham B, Wittfeld K, Wolf C, Wright C, Yang Q, Zhao W, Zijdenbos A, Jukema J, Sacco R, Kardia S, Amouyel P, Mosley T, Longstreth W, DeCarli C, van Duijn C, Schmidt R, Launer L, Grabe H, Seshadri S, Ikram M, Fornage M, Bis J, Kavousi M, Franceschini N, Isaacs A, Abecasis G, Schminke U, Post W, Smith A, Cupples L, Markus H, Schmidt R, Huffman J, Lehtimäki T, Baumert J, Münzel T, Heckbert S, Dehghan A, North K, Oostra B, Bevan S, Stoegerer E, Hayward C, Raitakari O, Meisinger C, Schillert A, Sanna S, Völzke H, Cheng Y, Thorsson B, Fox C, Rice K, Rivadeneira F, Nambi V, Halperin E, Petrovic K, Peltonen L, Wichmann H, Schnabel R, Dörr M, Parsa A, Aspelund T, Demissie S, Kathiresan S, Reilly M, Taylor K, Uitterlinden A, Couper D, Sitzer M, Kähönen M, Illig T, Wild P, Orru M, Lüdemann J, Shuldiner A, Eiriksdottir G, White C, Rotter J, Hofman A, Seissler J, Zeller T, Usala G, Ernst F, Launer L, D'Agostino R, O'Leary D, Ballantyne C, Thiery J, Ziegler A, Lakatta E, Chilukoti R, Harris T, Wolf P, Psaty B, Polak J, Li X, Rathmann W, Uda M, Boerwinkle E, Klopp N, Schmidt H, Wilson J, Viikari J, Koenig W, Blankenberg S, Newman A, Witteman J, Heiss G, van Duijn C, Scuteri A, Homuth G, Mitchell B, Gudnason V, O’Donnell C. Genetic and lifestyle risk factors for MRI-defined brain infarcts in a population-based setting. Neurology 2019, 92: 10.1212/wnl.0000000000006851. PMID: 30651383, PMCID: PMC6369905, DOI: 10.1212/wnl.0000000000006851.Peer-Reviewed Original ResearchPopulation-based cohortGenetic risk scoreBrain infarctsLifestyle risk factorsRisk factorsWhite matter hyperintensity burdenLarge population-based cohortPrevious cardiovascular diseaseVascular risk factorsPopulation-based settingBody mass indexSex-adjusted associationsCausal risk factorPopulation-based participantsAdditional large datasetsGenome-wide association studiesIschemic strokeBlood pressureRelated phenotypesHigh BPMass indexBP traitsCardiovascular diseaseRisk scoreGenetic risk loci
2016
Global, regional, and national comparative risk assessment of 79 behavioural, environmental and occupational, and metabolic risks or clusters of risks, 1990–2015: a systematic analysis for the Global Burden of Disease Study 2015
Collaborators G, Forouzanfar M, Afshin A, Alexander L, Anderson H, Bhutta Z, Biryukov S, Brauer M, Burnett R, Cercy K, Charlson F, Cohen A, Dandona L, Estep K, Ferrari A, Frostad J, Fullman N, Gething P, Godwin W, Griswold M, Hay S, Kinfu Y, Kyu H, Larson H, Liang X, Lim S, Liu P, Lopez A, Lozano R, Marczak L, Mensah G, Mokdad A, Moradi-Lakeh M, Naghavi M, Neal B, Reitsma M, Roth G, Salomon J, Sur P, Vos T, Wagner J, Wang H, Zhao Y, Zhou M, Aasvang G, Abajobir A, Abate K, Abbafati C, Abbas K, Abd-Allah F, Abdulle A, Abera S, Abraham B, Abu-Raddad L, Abyu G, Adebiyi A, Adedeji I, Ademi Z, Adou A, Adsuar J, Agardh E, Agarwal A, Agrawal A, Kiadaliri A, Ajala O, Akinyemiju T, Al-Aly Z, Alam K, Alam N, Aldhahri S, Aldridge R, Alemu Z, Ali R, Alkerwi A, Alla F, Allebeck P, Alsharif U, Altirkawi K, Martin E, Alvis-Guzman N, Amare A, Amberbir A, Amegah A, Amini H, Ammar W, Amrock S, Andersen H, Anderson B, Antonio C, Anwari P, Ärnlöv J, Artaman A, Asayesh H, Asghar R, Assadi R, Atique S, Avokpaho E, Awasthi A, Quintanilla B, Azzopardi P, Bacha U, Badawi A, Bahit M, Balakrishnan K, Barac A, Barber R, Barker-Collo S, Bärnighausen T, Barquera S, Barregard L, Barrero L, Basu S, Batis C, Bazargan-Hejazi S, Beardsley J, Bedi N, Beghi E, Bell B, Bell M, Bello A, Bennett D, Bensenor I, Berhane A, Bernabé E, Betsu B, Beyene A, Bhala N, Bhansali A, Bhatt S, Biadgilign S, Bikbov B, Bisanzio D, Bjertness E, Blore J, Borschmann R, Boufous S, Bourne R, Brainin M, Brazinova A, Breitborde N, Brenner H, Broday D, Brugha T, Brunekreef B, Butt Z, Cahill L, Calabria B, Campos-Nonato I, Cárdenas R, Carpenter D, Carrero J, Casey D, Castañeda-Orjuela C, Rivas J, Castro R, Catalá-López F, Chang J, Chiang P, Chibalabala M, Chimed-Ochir O, Chisumpa V, Chitheer A, Choi J, Christensen H, Christopher D, Ciobanu L, Coates M, Colquhoun S, Manzano A, Cooper L, Cooperrider K, Cornaby L, Cortinovis M, Crump J, Cuevas-Nasu L, Damasceno A, Dandona R, Darby S, Dargan P, Neves J, Davis A, Davletov K, de Castro E, De la Cruz-Góngora V, De Leo D, Degenhardt L, Del Gobbo L, del Pozo-Cruz B, Dellavalle R, Deribew A, Jarlais D, Dharmaratne S, Dhillon P, Diaz-Torné C, Dicker D, Ding E, Dorsey E, Doyle K, Driscoll T, Duan L, Dubey M, Duncan B, Elyazar I, Endries A, Ermakov S, Erskine H, Eshrati B, Esteghamati A, Fahimi S, Faraon E, Farid T, Farinha C, Faro A, Farvid M, Farzadfar F, Feigin V, Fereshtehnejad S, Fernandes J, Fischer F, Fitchett J, Fleming T, Foigt N, Foreman K, Fowkes F, Franklin R, Fürst T, Futran N, Gakidou E, Garcia-Basteiro A, Gebrehiwot T, Gebremedhin A, Geleijnse J, Gessner B, Giref A, Giroud M, Gishu M, Giussani G, Goenka S, Gomez-Cabrera M, Gomez-Dantes H, Gona P, Goodridge A, Gopalani S, Gotay C, Goto A, Gouda H, Gugnani H, Guillemin F, Guo Y, Gupta R, Gupta R, Gutiérrez R, Haagsma J, Hafezi-Nejad N, Haile D, Hailu G, Halasa Y, Hamadeh R, Hamidi S, Handal A, Hankey G, Hao Y, Harb H, Harikrishnan S, Haro J, Hassanvand M, Hassen T, Havmoeller R, Heredia-Pi I, Hernández-Llanes N, Heydarpour P, Hoek H, Hoffman H, Horino M, Horita N, Hosgood H, Hoy D, Hsairi M, Htet A, Hu G, Huang J, Husseini A, Hutchings S, Huybrechts I, Iburg K, Idrisov B, Ileanu B, Inoue M, Jacobs T, Jacobsen K, Jahanmehr N, Jakovljevic M, Jansen H, Jassal S, Javanbakht M, Jayaraman S, Jayatilleke A, Jee S, Jeemon P, Jha V, Jiang Y, Jibat T, Jin Y, Johnson C, Jonas J, Kabir Z, Kalkonde Y, Kamal R, Kan H, Karch A, Karema C, Karimkhani C, Kasaeian A, Kaul A, Kawakami N, Kazi D, Keiyoro P, Kemmer L, Kemp A, Kengne A, Keren A, Kesavachandran C, Khader Y, Khan A, Khan E, Khan G, Khang Y, Khatibzadeh S, Khera S, Khoja T, Khubchandani J, Kieling C, Kim C, Kim D, Kimokoti R, Kissoon N, Kivipelto M, Knibbs L, Kokubo Y, Kopec J, Koul P, Koyanagi A, Kravchenko M, Kromhout H, Krueger H, Ku T, Defo B, Kuchenbecker R, Bicer B, Kuipers E, Kumar G, Kwan G, Lal D, Lalloo R, Lallukka T, Lan Q, Larsson A, Latif A, Lawrynowicz A, Leasher J, Leigh J, Leung J, Levi M, Li X, Li Y, Liang J, Liu S, Lloyd B, Logroscino G, Lotufo P, Lunevicius R, MacIntyre M, Mahdavi, Majdan M, Majeed A, Malekzadeh R, Malta D, Manamo W, Mapoma C, Marcenes W, Martin R, Martinez-Raga J, Masiye F, Matsushita K, Matzopoulos R, Mayosi B, McGrath J, McKee M, Meaney P, Medina C, Mehari A, Mejia-Rodriguez F, Mekonnen A, Melaku Y, Memish Z, Mendoza W, Mensink G, Meretoja A, Meretoja T, Mesfin Y, Mhimbira F, Millear A, Miller T, Mills E, Mirarefin M, Misganaw A, Mock C, Mohammadi A, Mohammed S, Mola G, Monasta L, Hernandez J, Montico M, Morawska L, Mori R, Mozaffarian D, Mueller U, Mullany E, Mumford J, Murthy G, Nachega J, Naheed A, Nangia V, Nassiri N, Newton J, Ng M, Le Nguyen Q, Nisar M, Pete P, Norheim O, Norman R, Norrving B, Nyakarahuka L, Obermeyer C, Ogbo F, Oh I, Oladimeji O, Olivares P, Olsen H, Olusanya B, Olusanya J, Opio J, Oren E, Orozco R, Ortiz A, Ota E, Mahesh P, Pana A, Park E, Parry C, Parsaeian M, Patel T, Caicedo A, Patil S, Patten S, Patton G, Pearce N, Pereira D, Perico N, Pesudovs K, Petzold M, Phillips M, Piel F, Pillay J, Plass D, Polinder S, Pond C, Pope C, Pope D, Popova S, Poulton R, Pourmalek F, Prasad N, Qorbani M, Rabiee R, Radfar A, Rafay A, Rahimi-Movaghar V, Rahman M, Rahman M, Rahman S, Kumar R, Rajsic S, Raju M, Ram U, Rana S, Ranganathan K, Rao P, García C, Refaat A, Rehm C, Rehm J, Reinig N, Remuzzi G, Resnikoff S, Ribeiro A, Rivera J, Roba H, Rodriguez A, Rodriguez-Ramirez S, Rojas-Rueda D, Roman Y, Ronfani L, Roshandel G, Rothenbacher D, Roy A, Saleh M, Sanabria J, Sanchez-Riera L, Sanchez-Niño M, Sánchez-Pimienta T, Sandar L, Santomauro D, Santos I, Sarmiento-Suarez R, Sartorius B, Satpathy M, Savic M, Sawhney M, Schmidhuber J, Schmidt M, Schneider I, Schöttker B, Schutte A, Schwebel D, Scott J, Seedat S, Sepanlou S, Servan-Mori E, Shaddick G, Shaheen A, Shahraz S, Shaikh M, Levy T, Sharma R, She J, Sheikhbahaei S, Shen J, Sheth K, Shi P, Shibuya K, Shigematsu M, Shin M, Shiri R, Shishani K, Shiue I, Shrime M, Sigfusdottir I, Silva D, Silveira D, Silverberg J, Simard E, Sindi S, Singh A, Singh J, Singh P, Slepak E, Soljak M, Soneji S, Sorensen R, Sposato L, Sreeramareddy C, Stathopoulou V, Steckling N, Steel N, Stein D, Stein M, Stöckl H, Stranges S, Stroumpoulis K, Sunguya B, Swaminathan S, Sykes B, Szoeke C, Tabarés-Seisdedos R, Takahashi K, Talongwa R, Tandon N, Tanne D, Tavakkoli M, Taye B, Taylor H, Tedla B, Tefera W, Tegegne T, Tekle D, Terkawi A, Thakur J, Thomas B, Thomas M, Thomson A, Thorne-Lyman A, Thrift A, Thurston G, Tillmann T, Tobe-Gai R, Tobollik M, Topor-Madry R, Topouzis F, Towbin J, Tran B, Dimbuene Z, Tsilimparis N, Tura A, Tuzcu E, Tyrovolas S, Ukwaja K, Undurraga E, Uneke C, Uthman O, van Donkelaar A, van Os J, Varakin Y, Vasankari T, Veerman J, Venketasubramanian N, Violante F, Vollset S, Wagner G, Waller S, Wang J, Wang L, Wang Y, Weichenthal S, Weiderpass E, Weintraub R, Werdecker A, Westerman R, Whiteford H, Wijeratne T, Wiysonge C, Wolfe C, Won S, Woolf A, Wubshet M, Xavier D, Xu G, Yadav A, Yakob B, Yalew A, Yano Y, Yaseri M, Ye P, Yip P, Yonemoto N, Yoon S, Younis M, Yu C, Zaidi Z, Zaki M, Zhu J, Zipkin B, Zodpey S, Zuhlke L, Murray C. Global, regional, and national comparative risk assessment of 79 behavioural, environmental and occupational, and metabolic risks or clusters of risks, 1990–2015: a systematic analysis for the Global Burden of Disease Study 2015. The Lancet 2016, 388: 1659-1724. PMID: 27733284, PMCID: PMC5388856, DOI: 10.1016/s0140-6736(16)31679-8.Peer-Reviewed Original ResearchMeSH KeywordsAfrica South of the SaharaAfrica, NorthernAir Pollution, IndoorAlcohol DrinkingBiomarkersBlood GlucoseBody Mass IndexCholesterolCost of IllnessDisabled PersonsEnvironmental ExposureGlobal HealthHumansHypertensionLife ExpectancyMalnutritionMiddle EastOccupational ExposureQuality-Adjusted Life YearsRisk AssessmentRisk FactorsRisk-TakingSmokingSodium, DietarySubstance-Related DisordersUnsafe SexConceptsHigher body mass indexBody mass indexSocio-demographic IndexAttributable DALYsPlasma glucoseHousehold air pollutionMetabolic riskGlobal burdenClusters of risksDrug useChildhood undernutritionAttributable burdenDALY ratesChildhood underweightRisk factorsStudy 2015National comparative risk assessmentRisk Factors Study 2015Risk-deleted DALY ratesHigher systolic blood pressureWorld Cancer Research FundRisk-outcome pairsSummary exposure valueComparative risk assessment frameworkDisease Study 2015