2020
The Effect of Glucocorticoids on Angiogenesis in the Treatment of Solid Tumors.
Liu B, Goodwin JE. The Effect of Glucocorticoids on Angiogenesis in the Treatment of Solid Tumors. Journal Of Cellular Signaling 2020, 1: 42-49. PMID: 32728672, PMCID: PMC7388649, DOI: 10.33696/signaling.1.011.Peer-Reviewed Original ResearchSolid tumorsUsage of glucocorticoidsEffects of glucocorticoidsCommon solid tumorsRole of glucocorticoidsTreatment regimensCommon cancerInflammatory diseasesAdrenal cortexImmune disordersSynthetic glucocorticoidAngiostatic propertiesGlucocorticoidsSteroid hormonesCancer treatmentTumorsPathological processesRegimensCurrent reviewTreatmentAngiogenesisUnanswered questionsCircadian mannerMalignancyCancer
2011
Knockout of the vascular endothelial glucocorticoid receptor abrogates dexamethasone-induced hypertension
Goodwin JE, Zhang J, Gonzalez D, Albinsson S, Geller DS. Knockout of the vascular endothelial glucocorticoid receptor abrogates dexamethasone-induced hypertension. Journal Of Hypertension 2011, 29: 1347-1356. PMID: 21659825, PMCID: PMC3439131, DOI: 10.1097/hjh.0b013e328347da54.Peer-Reviewed Original ResearchConceptsEndothelial glucocorticoid receptorGlucocorticoid receptorMean blood pressure increaseKnockout animalsDexamethasone-induced hypertensionBlood pressure increaseCircadian BP rhythmForms of hypertensionEffects of glucocorticoidsNormal circadian BP rhythmPeripheral circadian clocksBaseline BPBP rhythmMmHg increaseContractile responseBP homeostasisResistance arteriolesTissue-specific knockoutFundamental physiologic processesDexamethasone treatmentHypertensionMouse modelControl animalsVascular endotheliumKnockout mice