2021
IFN Stimulates ACE2 Expression in Pediatric Airway Epithelial Cells
Salka K, Abutaleb K, Chorvinsky E, Thiruvengadam G, Arroyo M, Gomez JL, Gutierrez MJ, Pillai DK, Jaiswal JK, Nino G. IFN Stimulates ACE2 Expression in Pediatric Airway Epithelial Cells. American Journal Of Respiratory Cell And Molecular Biology 2021, 64: 515-518. PMID: 33544656, PMCID: PMC8008803, DOI: 10.1165/rcmb.2020-0352le.Peer-Reviewed Original Research
2018
Characterization of Sex-Based Dna Methylation Signatures in the Airways During Early Life
Nino C, Perez G, Isaza N, Gutierrez M, Gomez J, Nino G. Characterization of Sex-Based Dna Methylation Signatures in the Airways During Early Life. Scientific Reports 2018, 8: 5526. PMID: 29615635, PMCID: PMC5882800, DOI: 10.1038/s41598-018-23063-5.Peer-Reviewed Original ResearchConceptsX-linked genesDNA methylation signaturesDifferential methylationMethylation signaturesGenome-wide DNA methylationProtein coding transcriptsX chromosome dosageX-chromosome methylationEpigenomic marksMethylation patternsX chromosomeDNA methylationCpG sitesGenomic signaturesX-inactivationGenetic componentCoding transcriptsGenesMethylation signalsAirways of infantsInfants aged 1Independent populationsRespiratory phenotypeAirway expressionIndividual's sex
2016
Airway Secretory microRNAome Changes during Rhinovirus Infection in Early Childhood
Gutierrez M, Gomez J, Perez G, Pancham K, Val S, Pillai D, Giri M, Ferrante S, Freishtat R, Rose M, Preciado D, Nino G. Airway Secretory microRNAome Changes during Rhinovirus Infection in Early Childhood. PLOS ONE 2016, 11: e0162244. PMID: 27643599, PMCID: PMC5028059, DOI: 10.1371/journal.pone.0162244.Peer-Reviewed Original ResearchConceptsRV infectionHuman bronchial epithelial cellsAirway secretionsExtracellular vesiclesCause of asthma exacerbationsAirways of young childrenHuman RV infectionsNasal airway secretionsHsa-miR-155Air-liquid interfaceRegulates antiviral immunityMonitor respiratory conditionsSecretion of extracellular vesiclesModify gene expressionAirways of individualsPotential biological relevanceBronchial epithelial cellsAge-matched controlsInnate immune responseDevelopment of asthmaBioinformatics toolsGene datasetsGenetic communicationNoncoding RNA moleculesRNA molecules