2007
Ultrastructure of Dendritic Spines: Correlation Between Synaptic and Spine Morphologies
Arellano J, Benavides-Piccione R, DeFelipe J, Yuste R. Ultrastructure of Dendritic Spines: Correlation Between Synaptic and Spine Morphologies. Frontiers In Neuroscience 2007, 1: 131-143. PMID: 18982124, PMCID: PMC2518053, DOI: 10.3389/neuro.01.1.1.010.2007.Peer-Reviewed Original ResearchSpine head volumeDendritic spinesSynaptic strengthSpine morphologyLayer 2/3 pyramidal cellsPostsynaptic densityMouse visual cortexMost excitatory synapsesReady releasable poolPostsynaptic receptorsPyramidal cellsExcitatory synapsesHead volumeDistinguishable subtypesCortical circuitsGolgi impregnationVisual cortexParent dendriteSpine neckPSD areaSpineSynaptic featuresFunctional parametersNeck lengthNeck diameter
2002
Microstructure of the neocortex: Comparative aspects
DeFelipe J, Alonso-Nanclares L, Arellano J. Microstructure of the neocortex: Comparative aspects. Brain Cell Biology 2002, 31: 299-316. PMID: 12815249, DOI: 10.1023/a:1024130211265.Peer-Reviewed Original ResearchConceptsDifferent cortical areasCortical areasExtrinsic afferent systemsNeocortex of humansInhibitory GABAergic interneuronsDensity of excitatoryNumber of synapsesSpecific cortical circuitsDistinct cortical areasSpiny cellsInhibitory circuitsGABAergic interneuronsInhibitory synapsesNeocortical neuronsNeuronal elementsPyramidal cellsAfferent systemsCortical circuitsNeocortical circuitsCortical tissueNumber of neuronsNeocortexNeuronsExcitatoryBasic microcircuitThe neuropathology of temporal lobe epilepsy: primary and secondary changes in the cortical circuits and epileptogenicity.
DeFelipe Oroquieta J, Arellano J, Alonso L, Muñoz A. The neuropathology of temporal lobe epilepsy: primary and secondary changes in the cortical circuits and epileptogenicity. Revista De Neurologia 2002, 34: 401-8. PMID: 12040509, DOI: 10.33588/rn.3405.2001403.Peer-Reviewed Original ResearchConceptsTemporal lobe epilepsyPrimary epileptogenic regionEpileptogenic regionEpileptic activitySynaptic reorganizationLobe epilepsySpecific anatomical connectionsMesial sclerosisNeuronal lossPerilesional areaCommon pathologyInitial lesionCortical circuitsHippocampal formationNeuronal circuitsAnatomical connectionsCortical tissueSecondary changesEpilepsySimilar changesLesionsGliosisEpileptogenicitySclerosisPatients