2023
Diverse mechanisms of taste coding in Drosophila
Dweck H, Carlson J. Diverse mechanisms of taste coding in Drosophila. Science Advances 2023, 9: eadj7032. PMID: 37976361, PMCID: PMC10656072, DOI: 10.1126/sciadv.adj7032.Peer-Reviewed Original Research
2019
Robust olfactory responses in the absence of odorant binding proteins
Xiao S, Sun JS, Carlson JR. Robust olfactory responses in the absence of odorant binding proteins. ELife 2019, 8: e51040. PMID: 31651397, PMCID: PMC6814364, DOI: 10.7554/elife.51040.Peer-Reviewed Original ResearchConceptsOdorant binding proteinsOlfactory responsesBinding proteinAntennae of insectsHydrophobic odorantsSensilla typesOlfactory physiologyOlfactory sensillaFunctional typesBasiconic sensillaOBPsAntennal basiconic sensillaOdor receptorsSensillaProteinDiverse chemicalsInsectsOdorantsMutantsBehavioral responsesGenesOvipositionPhysiologyHigh levelsResponseOdor coding in the antenna of the tsetse fly Glossina morsitans
Soni N, Chahda JS, Carlson JR. Odor coding in the antenna of the tsetse fly Glossina morsitans. Proceedings Of The National Academy Of Sciences Of The United States Of America 2019, 116: 14300-14308. PMID: 31221757, PMCID: PMC6628836, DOI: 10.1073/pnas.1907075116.Peer-Reviewed Original ResearchConceptsTsetse fly Glossina morsitansClasses of sensillaFruit flyPhysiological analysisAlarm pheromoneDifferent response dynamicsOlfactory sensillaFly antennaOlfactory cuesCellular basisWide diversityTsetse fliesSensillaFliesDifferent functionsDifferent odor stimuliGlossina morsitansPheromoneTsetseFunctional organizationHostDrosophilaMorphological typesOdorantsStriking differenceThe molecular and cellular basis of olfactory response to tsetse fly attractants
Chahda JS, Soni N, Sun JS, Ebrahim SAM, Weiss BL, Carlson JR. The molecular and cellular basis of olfactory response to tsetse fly attractants. PLOS Genetics 2019, 15: e1008005. PMID: 30875383, PMCID: PMC6420007, DOI: 10.1371/journal.pgen.1008005.Peer-Reviewed Original ResearchConceptsOlfactory receptor neuronsSensory pitsCellular basisHeterologous expression systemTsetse fly Glossina morsitansTerrestrial habitatsExpression systemGene expressionEmpty neuronAnimal matterOlfactory responsesSpecialized subtypesMajor vectorStrong attractantReceptor gene expressionG. fuscipesDrosophilaMalarial parasitesReceptor neuronsFliesAttractantsDevastating diseaseOlfactory systemBlood of humansGlossina morsitans
2012
Non-synaptic inhibition between grouped neurons in an olfactory circuit
Su CY, Menuz K, Reisert J, Carlson JR. Non-synaptic inhibition between grouped neurons in an olfactory circuit. Nature 2012, 492: 66-71. PMID: 23172146, PMCID: PMC3518700, DOI: 10.1038/nature11712.Peer-Reviewed Original ResearchConceptsOlfactory receptor neuronsDrosophila olfactory receptor neuronsMalaria mosquito AnophelesMosquito AnophelesMammalian taste budsSustained responseInsect controlLateral inhibitionBroad occurrenceChemosensory sensillaOlfactory behaviorTransient activationSensory organsMarked compartmentalizationOlfactory circuitFunctional impactReceptor neuronsReceptor cellsOlfactory informationInhibitionInsectsTaste budsNeuronsCompartmentalizationBuds
2011
Scent of a Human
Carlson JR, Carey AF. Scent of a Human. Scientific American 2011, 305: 76-79. PMID: 21717963, DOI: 10.1038/scientificamerican0711-76.Peer-Reviewed Original Research
2008
Translation of Sensory Input into Behavioral Output via an Olfactory System
Kreher SA, Mathew D, Kim J, Carlson JR. Translation of Sensory Input into Behavioral Output via an Olfactory System. Neuron 2008, 59: 110-124. PMID: 18614033, PMCID: PMC2496968, DOI: 10.1016/j.neuron.2008.06.010.Peer-Reviewed Original Research
2007
Receptors and Neurons for Fly Odors in Drosophila
van Naters W, Carlson JR. Receptors and Neurons for Fly Odors in Drosophila. Current Biology 2007, 17: 606-612. PMID: 17363256, PMCID: PMC1876700, DOI: 10.1016/j.cub.2007.02.043.Peer-Reviewed Original ResearchConceptsCis-vaccenyl acetateOlfactory receptor neuronsTrichoid sensillaAnti-aphrodisiac pheromoneReceptor gene familyVirgin femalesVivo expression systemGene familyMate recognitionMating partnersDrosophila antennaExpression systemORN populationCellular basisReceptor neuronsYield responseSensillaMale extractsElectrophysiological analysisFood odorsReceptorsDrosophilaMajor typesPheromoneFemales
2006
Insects as chemosensors of humans and crops
van der Goes van Naters W, Carlson JR. Insects as chemosensors of humans and crops. Nature 2006, 444: 302-307. PMID: 17108954, DOI: 10.1038/nature05403.Peer-Reviewed Original Research
2005
The Molecular Basis of Odor Coding in the Drosophila Larva
Kreher SA, Kwon JY, Carlson JR. The Molecular Basis of Odor Coding in the Drosophila Larva. Neuron 2005, 46: 445-456. PMID: 15882644, DOI: 10.1016/j.neuron.2005.04.007.Peer-Reviewed Original ResearchConceptsOlfactory receptor neuronsDrosophila larvaeMolecular basisVivo expression systemDifferent olfactory systemsFamily of receptorsSingle olfactory receptor neuronsLarval brainSpecificity mapsLarval antennal lobeExpression systemMolecular mechanismsOdor codingOdor receptorsReceptor neuronsIndividual receptorsAntennal lobeLongstanding observationGenesOlfactory systemLarvaeBreadth of tuningSingle glomerulusReceptorsOdor information
2004
The Molecular Basis of Odor Coding in the Drosophila Antenna
Hallem EA, Ho MG, Carlson JR. The Molecular Basis of Odor Coding in the Drosophila Antenna. Cell 2004, 117: 965-979. PMID: 15210116, DOI: 10.1016/j.cell.2004.05.012.Peer-Reviewed Original ResearchConceptsOlfactory receptor neuronsDrosophila antennaMolecular basisOdorant receptor repertoireFunctional analysisReceptor repertoireOlfactory organOdor codingReceptor neuronsIndividual receptorsSame cellsReceptor transductionNumber of receptorsNeuron mapReceptorsRepertoireBreadth of tuningTransductionDifferent odorantsInhibitory responsesOdorantsElectrophysiological recordingsNeuronsCellsVivoMosquito receptor for human-sweat odorant
Hallem EA, Nicole Fox A, Zwiebel LJ, Carlson JR. Mosquito receptor for human-sweat odorant. Nature 2004, 427: 212-213. PMID: 14724626, DOI: 10.1038/427212a.Peer-Reviewed Original Research
2003
Integrating the Molecular and Cellular Basis of Odor Coding in the Drosophila Antenna
Dobritsa AA, van Naters W, Warr CG, Steinbrecht RA, Carlson JR. Integrating the Molecular and Cellular Basis of Odor Coding in the Drosophila Antenna. Neuron 2003, 37: 827-841. PMID: 12628173, DOI: 10.1016/s0896-6273(03)00094-1.Peer-Reviewed Original ResearchConceptsAb3A neuronsEctopic expressionTransgenic rescue experimentsWild-type cellsDrosophila olfactory systemOdor ligandsDeletion mutantsDrosophila antennaCells identifiesGene expressionRescue experimentsCellular mapsSexual dimorphismReceptor gene expressionCellular basisOr22aOdor receptorsReceptor geneSingle cellsGenesOlfactory systemExpressionOdor codingDendritic membraneCells
2001
Odor Coding in the Drosophila Antenna
de Bruyne M, Foster K, Carlson J. Odor Coding in the Drosophila Antenna. Neuron 2001, 30: 537-552. PMID: 11395013, DOI: 10.1016/s0896-6273(01)00289-6.Peer-Reviewed Original Research
1999
Olfactory Adaptation Depends on the Trp Ca2+Channel in Drosophila
Störtkuhl K, Hovemann B, Carlson J. Olfactory Adaptation Depends on the Trp Ca2+Channel in Drosophila. Journal Of Neuroscience 1999, 19: 4839-4846. PMID: 10366618, PMCID: PMC6782652, DOI: 10.1523/jneurosci.19-12-04839.1999.Peer-Reviewed Original Research