2010
Confirmation and Generalization of an Alcohol-Dependence Locus on Chromosome 10q
Panhuysen CI, Kranzler HR, Yu Y, Weiss RD, Brady K, Poling J, Farrer LA, Gelernter J. Confirmation and Generalization of an Alcohol-Dependence Locus on Chromosome 10q. Neuropsychopharmacology 2010, 35: 1325-1332. PMID: 20147890, PMCID: PMC2855759, DOI: 10.1038/npp.2010.1.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgedAlcohol-Induced Disorders, Nervous SystemAlcoholismBlack or African AmericanChromosome MappingChromosomes, Human, Pair 10FemaleGene FrequencyGenetic LinkageGenetic Predisposition to DiseaseGenome-Wide Association StudyGenotypeHumansMaleMiddle AgedPenetranceWhite PeopleYoung AdultConceptsLinkage peakLOD scoreGenome-wide linkage scanLinkage analysisSignificant linkage peakNon-parametric linkage analysisParametric linkage analysisChromosome 10 markersSignificant LOD scorePeak lod scoreGenome scanLinkage scanRisk lociChromosome 10Chromosome 7Suggestive linkageAA sampleAD-related traitsLociChromosome 10qDistinct populationsTraitsEA samplesFamilyAD phenotype
2005
ADH4 Gene Variation is Associated with Alcohol Dependence and Drug Dependence in European Americans: Results from HWD Tests and Case–Control Association Studies
Luo X, Kranzler HR, Zuo L, Lappalainen J, Yang BZ, Gelernter J. ADH4 Gene Variation is Associated with Alcohol Dependence and Drug Dependence in European Americans: Results from HWD Tests and Case–Control Association Studies. Neuropsychopharmacology 2005, 31: 1085-1095. PMID: 16237392, DOI: 10.1038/sj.npp.1300925.Peer-Reviewed Original ResearchAdultAlcohol DehydrogenaseAlcohol-Induced Disorders, Nervous SystemAlcoholismAmericasDNA Mutational AnalysisEuropeFemaleGenes, RecessiveGenetic MarkersGenetic Predisposition to DiseaseGenetic TestingGenetic VariationGenotypeHaplotypesHumansLinkage DisequilibriumMaleMiddle AgedPolymorphism, Single NucleotidePromoter Regions, GeneticSubstance-Related DisordersWhite People