ATP Synthase Is Responsible for Maintaining Mitochondrial Membrane Potential in Bloodstream Form Trypanosoma brucei
Brown SV, Hosking P, Li J, Williams N. ATP Synthase Is Responsible for Maintaining Mitochondrial Membrane Potential in Bloodstream Form Trypanosoma brucei. MSphere 2006, 5: 45-53. PMID: 16400167, PMCID: PMC1360250, DOI: 10.1128/ec.5.1.45-53.2006.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsCarbonyl Cyanide m-Chlorophenyl HydrazoneCell ProliferationFlow CytometryHydrolysisMembrane PotentialsMitochondriaMitochondrial Proton-Translocating ATPasesOligomycinsRNA InterferenceRNA, MessengerTetracyclineTrypanosoma brucei bruceiConceptsMitochondrial membrane potentialATP synthaseRNA interferenceBeta subunitProtein levelsAlpha subunitMembrane potentialBloodstream form T. bruceiSteady-state transcript levelsF1-ATPase alphaInduction of RNAiMitochondrion of TrypanosomaWild-type cellsBloodstream form TrypanosomaAlpha subunit transcriptsRNAi knockdownRNAi cellsT. bruceiTranscript levelsUninduced cellsBloodstream formsBeta subunit transcriptsSubunitsKrebs cycleFluorescence microscopy