1998
Gene length and codon usage bias in Drosophila melanogaster , Saccharomyces cerevisiae and Escherichia coli
Moriyama E, Powell J. Gene length and codon usage bias in Drosophila melanogaster , Saccharomyces cerevisiae and Escherichia coli. Nucleic Acids Research 1998, 26: 3188-3193. PMID: 9628917, PMCID: PMC147681, DOI: 10.1093/nar/26.13.3188.Peer-Reviewed Original ResearchConceptsCodon usage biasUsage biasGene lengthDrosophila melanogasterLong genesHigher codon usage biasRibosomal protein genesEscherichia coliSynonymous codon usage biasD. melanogasterTranslational selectionShort genesProtein geneTranslational efficiencyEukaryotesMelanogasterGenesExpression levelsSaccharomycesEffective numberColiProkaryotesCodonOrganismsProtein
1997
Evolution of codon usage bias in Drosophila
Powell J, Moriyama E. Evolution of codon usage bias in Drosophila. Proceedings Of The National Academy Of Sciences Of The United States Of America 1997, 94: 7784-7790. PMID: 9223264, PMCID: PMC33704, DOI: 10.1073/pnas.94.15.7784.Peer-Reviewed Original ResearchConceptsCodon usage biasHigher codon usage biasUsage biasBiased genesMutation biasSynonymous sitesCodon biasAmino acidsLow codon usage biasDrosophila genesDNA evolutionEffect of recombinationSmall geneIndividual amino acidsLong genesSynonymous substitutionsTRNA poolPreferred codonsSynonymous polymorphismWobble positionDrosophilaSame nucleotideSelection hypothesisGenesLines of evidence
1996
Intraspecific nuclear DNA variation in Drosophila.
Moriyama E, Powell J. Intraspecific nuclear DNA variation in Drosophila. Molecular Biology And Evolution 1996, 13: 261-277. PMID: 8583899, DOI: 10.1093/oxfordjournals.molbev.a025563.Peer-Reviewed Original ResearchConceptsD. melanogasterDNA polymorphismsD. simulansD. pseudoobscuraNeutral theorySpecies of DrosophilaNuclear DNA variationMcDonald-Kreitman testNon-coding DNALevel of polymorphismFourfold degenerate sitesCodon usage biasLevel of variationReplacement polymorphismsNucleotide heterozygosityNoncoding DNAHKA testTajima's testReplacement substitutionsDNA variationSilent sitesGenetic codeAutosomal genesPopulation historyUsage bias