2021
Evaluating public acceptability of a potential Lyme disease vaccine using a population-based, cross-sectional survey in high incidence areas of the United States
Hook SA, Hansen AP, Niesobecki SA, Meek JI, Bjork JKH, Kough EM, Peterson MS, Schiffman EK, Rutz HJ, Rowe AJ, White JL, Peel JL, Biggerstaff BJ, Hinckley AF. Evaluating public acceptability of a potential Lyme disease vaccine using a population-based, cross-sectional survey in high incidence areas of the United States. Vaccine 2021, 40: 298-305. PMID: 34895785, DOI: 10.1016/j.vaccine.2021.11.065.Peer-Reviewed Original ResearchConceptsLyme disease vaccineDisease vaccineSurvey-weighted descriptive statisticsMultivariable multinomial logistic regression modelsCross-sectional studyLyme disease incidenceHigh incidence areaCross-sectional surveyLogistic regression modelsSafety concernsMultinomial logistic regression modelsVaccine uptakeAdults 45Vaccine parametersVaccine candidatesVaccine attitudesPrevention optionsHealthcare providersWeb-based surveyVaccineSociodemographic characteristicsIncidence areaLyme diseaseDisease incidenceIncidence
2016
Effectiveness of Residential Acaricides to Prevent Lyme and Other Tick-borne Diseases in Humans
Hinckley A, Meek J, Ray J, Niesobecki S, Connally N, Feldman K, Jones E, Backenson P, White J, Lukacik G, Kay A, Miranda W, Mead P. Effectiveness of Residential Acaricides to Prevent Lyme and Other Tick-borne Diseases in Humans. The Journal Of Infectious Diseases 2016, 214: 182-188. PMID: 26740276, PMCID: PMC10874626, DOI: 10.1093/infdis/jiv775.Peer-Reviewed Original ResearchConceptsTick-borne diseasesHuman-tick encountersMajor public health concernPlacebo-controlled trialMedical record reviewHuman tick-borne diseasesReports of illnessPublic health concernPublic health authoritiesTick-borne diseaseRecord reviewTick biteTick exposureTreatment groupsHealth authoritiesDiseaseHealth concernQuesting ticksHuman outcomesTicksUse of acaricidesIllnessIncidenceTrialsWeeksBurden of Nursing Home-Onset Clostridium difficile Infection in the United States: Estimates of Incidence and Patient Outcomes
Hunter J, Mu Y, Dumyati G, Farley M, Winston L, Johnston H, Meek J, Perlmutter R, Holzbauer S, Beldavs Z, Phipps E, Dunn J, Cohen J, Avillan J, Stone N, Gerding D, McDonald L, Lessa F. Burden of Nursing Home-Onset Clostridium difficile Infection in the United States: Estimates of Incidence and Patient Outcomes. Open Forum Infectious Diseases 2016, 3: ofv196. PMID: 26798767, PMCID: PMC4719744, DOI: 10.1093/ofid/ofv196.Peer-Reviewed Original ResearchClostridium difficile infectionDifficile infectionPatient outcomesPopulation-based surveillanceAcute care settingAppropriate antibiotic useEstimates of incidenceMedian ageSubstantial morbidityPositive stoolsMedical recordsRisk factorsAdvanced ageAntibiotic useInfection preventionAntibiotic exposureHome residentsNational incidenceCare settingsPositive specimenNational estimatesIncidenceSpecimen collectionAgeStool
2015
Burden of Clostridium difficile Infection in the United States
Lessa F, Mu Y, Bamberg W, Beldavs Z, Dumyati G, Dunn J, Farley M, Holzbauer S, Meek J, Phipps E, Wilson L, Winston L, Cohen J, Limbago B, Fridkin S, Gerding D, McDonald L. Burden of Clostridium difficile Infection in the United States. New England Journal Of Medicine 2015, 372: 825-834. PMID: 25714160, PMCID: PMC10966662, DOI: 10.1056/nejmoa1408913.Peer-Reviewed Original ResearchConceptsClostridium difficile infectionDifficile infectionFirst recurrenceHealth care-associated infectionsCommunity-associated infectionsC. difficile infectionCare-associated infectionsPersons 65 yearsLaboratory-based surveillanceType 1 strainsNumber of deathsNational incidenceMolecular typingC. difficileInfectionIncidenceDeathUnited StatesRecurrenceGeographic areasSample of casesEstimated numberRegression modelsActive populationHealth
2002
Spatial Analysis of Human Granulocytic Ehrlichiosis near Lyme, Connecticut - Volume 8, Number 9—September 2002 - Emerging Infectious Diseases journal - CDC
Chaput EK, Meek JI, Heimer R. Spatial Analysis of Human Granulocytic Ehrlichiosis near Lyme, Connecticut - Volume 8, Number 9—September 2002 - Emerging Infectious Diseases journal - CDC. Emerging Infectious Diseases 2002, 8: 943-948. PMID: 12194771, PMCID: PMC2732548, DOI: 10.3201/eid0809.020103.Peer-Reviewed Original Research
2000
The Emergence of Another Tickborne Infection in the 12-Town Area around Lyme, Connecticut: Human Granulocytic Ehrlichiosis
IJdo J, Meek J, Cartter M, Magnarelli L, Wu C, Tenuta S, Fikrig E, Ryder R. The Emergence of Another Tickborne Infection in the 12-Town Area around Lyme, Connecticut: Human Granulocytic Ehrlichiosis. The Journal Of Infectious Diseases 2000, 181: 1388-1393. PMID: 10751139, DOI: 10.1086/315389.Peer-Reviewed Original ResearchConceptsHuman granulocytic ehrlichiosisTickborne infectionProspective population-based surveillanceGranulocytic ehrlichiosisCommon tickborne infectionPopulation-based surveillancePrimary care providersSubset of seraIndirect fluorescent antibody methodIllness suggestiveCare providersLaboratory evidenceImportant causeProbable casesFluorescent antibody methodImmunoblot assayLyme diseaseInfectionAntibody methodIncidenceEhrlichiosisLymeMorbidityDiseaseSuggestive