Clonidine Treatment of Gilles de la Tourette's Syndrome
Leckman JF, Hardin MT, Riddle MA, Stevenson J, Ort SI, Cohen DJ. Clonidine Treatment of Gilles de la Tourette's Syndrome. JAMA Psychiatry 1991, 48: 324-328. PMID: 2009034, DOI: 10.1001/archpsyc.1991.01810280040006.Peer-Reviewed Original ResearchMeSH KeywordsAdministration, OralAdolescentAdultClonidineDouble-Blind MethodDrug Administration ScheduleFemaleHumansMaleMiddle AgedOutcome and Process Assessment, Health CareParentsPersonality InventoryPlacebosPsychiatric Status Rating ScalesTourette SyndromeVideotape RecordingConceptsGilles de la Tourette's syndromeLa Tourette's syndromeClonidine treatmentTourette syndromeTic severityDouble-blind clinical trialMotor tic severityClinical trialsClonidine hydrochlorideBehavioral symptomsClinical ratingsSyndromeMagnitude of responseClonidineTreatmentParent-rated measuresSeveritySubjectsPlaceboVideotaped interviewGroupSymptomsCliniciansHyperactivityTrials