2000
Bile salt excretion in skate liver is mediated by a functional analog of Bsep/Spgp, the bile salt export pump
Ballatori N, Rebbeor J, Connolly G, Seward D, Lenth B, Henson J, Sundaram P, Boyer J. Bile salt excretion in skate liver is mediated by a functional analog of Bsep/Spgp, the bile salt export pump. AJP Gastrointestinal And Liver Physiology 2000, 278: g57-g63. PMID: 10644562, DOI: 10.1152/ajpgi.2000.278.1.g57.Peer-Reviewed Original ResearchConceptsTransport activityPlasma membrane vesiclesApparent molecular massVertebrate evolutionATP-dependent componentMultidrug resistance protein 1Similar transport activityFunctional characterizationPlasma membraneApical localizationCanalicular membraneResistance protein 1Liver plasma membrane vesiclesATP-dependent uptakeSkate liverMembrane vesiclesWestern blot analysisDominant protein bandsMammalian liverMolecular massLittle skateFunctional analogueProtein 1Raja erinaceaCanalicular multidrug resistance
1991
Mechanism of mercurial inhibition of sodium-coupled alanine uptake in liver plasma membrane vesicles from Raja erinacea
Sellinger M, Ballatori N, Boyer J. Mechanism of mercurial inhibition of sodium-coupled alanine uptake in liver plasma membrane vesicles from Raja erinacea. Toxicology And Applied Pharmacology 1991, 107: 369-376. PMID: 1994517, DOI: 10.1016/0041-008x(91)90216-2.Peer-Reviewed Original ResearchConceptsDependent alanine uptakePlasma membrane vesiclesMembrane vesiclesAlanine uptakePrimitive vertebratesPlasma membraneTransport proteinsConcentration-dependent mechanismLiver plasma membrane vesiclesMicroM HgCl2Mammalian hepatocytesAlanine carrierSulfhydryl groupsLittle skateMembrane integrityRaja erinaceaDirect interactionVesiclesVesicle integrityMembrane permeabilityMercurial inhibitionUptake rateDose-dependent mannerHgCl2 concentrationsLiver plasma membranes
1987
Anion transport in basolateral (sinusoidal) liver plasma-membrane vesicles of the little skate (Raja erinacea)
Hugentobler G, Fricker G, Boyer J, Meier P. Anion transport in basolateral (sinusoidal) liver plasma-membrane vesicles of the little skate (Raja erinacea). Biochemical Journal 1987, 247: 589-595. PMID: 3426551, PMCID: PMC1148453, DOI: 10.1042/bj2470589.Peer-Reviewed Original ResearchMeSH Keywords4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid4,4'-Diisothiocyanostilbene-2,2'-Disulfonic AcidAnimalsBiological TransportCarbonyl Cyanide m-Chlorophenyl HydrazoneCell MembraneCholic AcidCholic AcidsElectric FishHydrogen-Ion ConcentrationIn Vitro TechniquesLiverMaleProbenecidSkates, FishSulfatesConceptsPlasma membrane vesiclesBasolateral liver plasma membrane vesiclesSulfate uptakeLiver plasma membrane vesiclesProtonophore carbonyl cyanideSulfate transport systemVertebrate evolutionMammalian liver cellsPH-equilibrated conditionsTransmembrane transportPH gradientLittle skateRaja erinaceaUptake 5Carbonyl cyanideCI inhibitionAnion transport inhibitorAlkaline pH gradientVesiclesAnion transportSkate hepatocytesCertain organic anionsUptakeLiver cellsElasmobranchs
1985
The effect of ethanol and calcium on fluid state of plasma membranes of rat hepatocytes
Mills P, Meier P, Boyer J, Gordon E. The effect of ethanol and calcium on fluid state of plasma membranes of rat hepatocytes. Alcohol 1985, 2: 153-156. PMID: 4015830, DOI: 10.1016/0741-8329(85)90034-5.Peer-Reviewed Original ResearchConceptsMembrane protein functionProtein functionMembrane fluidityCanalicular plasma membrane vesiclesPlasma membrane vesiclesOverall cellular activityMembrane lipid fluidityPlasma membraneMembrane preparationsMembrane vesiclesCellular activitiesImportant regulatorLipid fluidityMembrane perturbantsFluorescence polarizationRat hepatocytesFluidityBlLPMRegulatorUptakeUptake of taurocholateVesiclesMillipore filtration technique