Featured Publications
Sex differences in outcomes after coronary artery bypass grafting: a pooled analysis of individual patient data
Gaudino M, Di Franco A, Alexander JH, Bakaeen F, Egorova N, Kurlansky P, Boening A, Chikwe J, Demetres M, Devereaux PJ, Diegeler A, Dimagli A, Flather M, Hameed I, Lamy A, Lawton JS, Reents W, Robinson NB, Audisio K, Rahouma M, Serruys PW, Hara H, Taggart DP, Girardi LN, Fremes SE, Benedetto U. Sex differences in outcomes after coronary artery bypass grafting: a pooled analysis of individual patient data. European Heart Journal 2021, 43: 18-28. PMID: 34338767, PMCID: PMC8851663, DOI: 10.1093/eurheartj/ehab504.Peer-Reviewed Original ResearchMeSH KeywordsAgedCoronary Artery BypassCoronary Artery DiseaseFemaleHumansMaleMyocardial InfarctionPercutaneous Coronary InterventionSex CharacteristicsStrokeTreatment OutcomeConceptsCoronary artery bypassIndividual patient dataMyocardial infarctionArtery bypassCause mortalityWorse outcomesMultiple arterial graftingPatient dataOff-pump surgeryOutcomes of womenCABG trialBaseline characteristicsPatients 75Secondary outcomesPrimary outcomeArterial graftingCox regressionPooled analysisSurgical techniqueHigh riskHigh incidenceSimilar mortalitySystematic reviewRisk adjustmentMortalitySystematic Assessment of Online Health Information for Coronary Revascularization
Hameed I, Hameed NUF, Oakley CT, Gambardella I, Bravo C, Angiolillo DJ, Gaudino M. Systematic Assessment of Online Health Information for Coronary Revascularization. JAMA Internal Medicine 2021, 181: 1003-1006. PMID: 33871563, PMCID: PMC8056308, DOI: 10.1001/jamainternmed.2021.1051.Peer-Reviewed Original ResearchMeSH KeywordsCoronary Artery BypassCoronary Artery DiseaseHumansMyocardial RevascularizationPatient Education as TopicPercutaneous Coronary InterventionTreatment OutcomeConsiderations on the Management of Acute Postoperative Ischemia After Cardiac Surgery: A Scientific Statement From the American Heart Association
Gaudino M, Dangas G, Angiolillo D, Brodt J, Chikwe J, DeAnda A, Hameed I, Rodgers M, Sandner S, Sun L, Yong C, Council O. Considerations on the Management of Acute Postoperative Ischemia After Cardiac Surgery: A Scientific Statement From the American Heart Association. Circulation 2023, 148: 442-454. PMID: 37345559, DOI: 10.1161/cir.0000000000001154.Peer-Reviewed Original ResearchMeSH KeywordsAmerican Heart AssociationCardiac Surgical ProceduresCoronary Artery DiseaseHumansIschemiaMyocardial IschemiaPostoperative ComplicationsConceptsPostoperative myocardial ischemiaCardiac surgeryMyocardial ischemiaRedo coronary artery bypassCoronary artery bypassLife-threatening complicationsPercutaneous coronary interventionAmerican Heart AssociationLow methodological qualityArtery bypassPostoperative ischemiaCoronary interventionPrompt diagnosisPostoperative careHeart AssociationClinical guidanceSurgical proceduresMethodological qualityCurrent evidenceSurgeryIschemiaMultidisciplinary groupDiagnosisScientific statementConservative strategy
2021
Comparison of SYNTAX score strata effects of percutaneous and surgical revascularization trials: A meta-analysis
Gaudino M, Hameed I, Di Franco A, Naik A, Demetres M, Biondi-Zoccai G, Bangalore S. Comparison of SYNTAX score strata effects of percutaneous and surgical revascularization trials: A meta-analysis. Journal Of Thoracic And Cardiovascular Surgery 2021, 165: 1405-1413.e13. PMID: 34176619, PMCID: PMC8805094, DOI: 10.1016/j.jtcvs.2021.05.036.Peer-Reviewed Original ResearchMeSH KeywordsCoronary Artery BypassCoronary Artery DiseaseHumansIncidencePercutaneous Coronary InterventionRisk FactorsTreatment OutcomeConceptsPercutaneous coronary interventionCoronary artery bypassIncidence rate ratiosCoronary interventionArtery bypassCerebrovascular eventsSYNTAX scoreMultivessel diseaseCause mortalityStatistical heterogeneityRate ratioSystematic reviewCardiac Surgery (SYNTAX) scoreSYNTAX score tertilesCochrane Library databasesMain analysisSignificant statistical heterogeneityRandom-effects modelRevascularization TrialScore tertilesSecondary outcomesSurgery scoreRisk stratificationLibrary databasesNonsignificant increaseAngiographic Patency of Coronary Artery Bypass Conduits: A Network Meta‐Analysis of Randomized Trials
Gaudino M, Hameed I, Robinson NB, Ruan Y, Rahouma M, Naik A, Weidenmann V, Demetres M, Tam D, Hare DL, Girardi LN, Biondi‐Zoccai G, Fremes S. Angiographic Patency of Coronary Artery Bypass Conduits: A Network Meta‐Analysis of Randomized Trials. Journal Of The American Heart Association 2021, 10: e019206. PMID: 33686866, PMCID: PMC8174193, DOI: 10.1161/jaha.120.019206.Peer-Reviewed Original ResearchConceptsCoronary artery bypass conduitsTouch saphenous veinAngiographic patency ratesRadial arterySaphenous veinPatency ratesGraft occlusionRandomized trialsBypass conduitRight internal thoracic arteryTouch saphenous vein graftsCoronary bypass surgerySaphenous vein graftsGraft occlusion rateInternal thoracic arteryBest conduitNetwork Meta-AnalysisSystematic literature searchGastroepiploic arteryBypass surgeryPrimary outcomeThoracic arteryAngiographic patencyVein graftsOcclusion rate
2020
Overall and Cause-Specific Mortality in Randomized Clinical Trials Comparing Percutaneous Interventions With Coronary Bypass Surgery
Gaudino M, Hameed I, Farkouh ME, Rahouma M, Naik A, Robinson NB, Ruan Y, Demetres M, Biondi-Zoccai G, Angiolillo DJ, Bagiella E, Charlson ME, Benedetto U, Ruel M, Taggart DP, Girardi LN, Bhatt DL, Fremes SE. Overall and Cause-Specific Mortality in Randomized Clinical Trials Comparing Percutaneous Interventions With Coronary Bypass Surgery. JAMA Internal Medicine 2020, 180: 1638-1646. PMID: 33044497, PMCID: PMC7551235, DOI: 10.1001/jamainternmed.2020.4748.Peer-Reviewed Original ResearchConceptsPercutaneous coronary interventionRandomized clinical trialsCause-specific mortalityCoronary artery diseaseBare metal stentsNoncardiac mortalityCause mortalityCoronary interventionArtery diseaseClinical trialsTrials of PCIEnd pointLeft main diseaseCoronary artery bypassStudy end pointCoronary bypass surgeryData extractionTreatment of patientsCochrane Library databasesPreferred Reporting ItemsRandom-effects modelArtery bypassCardiac mortalityRevascularization TrialBypass surgerySurgeons’ Coronary Bypass Practice Patterns in the United States
Gaudino M, Rahouma M, Habib RH, Hameed I, Robinson NB, Farrington WJ, Fremes S, Schwann TA, Girardi LN. Surgeons’ Coronary Bypass Practice Patterns in the United States. Journal Of The American College Of Cardiology 2020, 76: 1714-1715. PMID: 33004137, DOI: 10.1016/j.jacc.2020.07.064.Peer-Reviewed Original ResearchSex‐related differences in outcomes after coronary artery bypass surgery—A patient‐level pooled analysis of randomized controlled trials: rationale and study protocol
Gaudino M, Alexander JH, Egorova N, Kurlansky P, Lamy A, Bakaeen F, Hameed I, Di Franco A, Demetres M, Robinson NB, Chikwe J, Lawton JS, Devereaux PJ, Taggart DP, Flather M, Reents W, Boening A, Diegeler A, Girardi LN, Fremes SE, Benedetto U. Sex‐related differences in outcomes after coronary artery bypass surgery—A patient‐level pooled analysis of randomized controlled trials: rationale and study protocol. Journal Of Cardiac Surgery 2020, 35: 2754-2758. PMID: 32720394, DOI: 10.1111/jocs.14903.Peer-Reviewed Original ResearchConceptsSex-related differencesPooled analysisSystematic reviewPatient-level pooled analysisCoronary artery bypass surgeryMultiple arterial graftsArtery bypass surgeryCoronary artery bypassLong-term followSex-related outcomesTreatment effectsPreferred Reporting ItemsSystematic literature searchPeer-reviewed scientific journalsImpact of sexDifferential treatment effectsCABG studiesArtery bypassCause mortalityPrimary endpointBypass surgeryArterial graftsMyocardial infarctionStudy protocolProspective RegisterEffect of Concomitant Coronary Artery Bypass Grafting on Outcomes of Ascending Aorta Replacement
Robinson NB, Hameed I, Naik A, Ishtiaq MF, Rahouma M, Girardi LN, Gaudino M. Effect of Concomitant Coronary Artery Bypass Grafting on Outcomes of Ascending Aorta Replacement. The Annals Of Thoracic Surgery 2020, 110: 2041-2046. PMID: 32343949, PMCID: PMC7799918, DOI: 10.1016/j.athoracsur.2020.03.070.Peer-Reviewed Original ResearchConceptsMajor adverse eventsAorta replacementOperative mortalityConcomitant CABGRisk of MAEsConcomitant coronary artery bypassCoronary artery bypass graftEnd pointConcomitant coronary revascularizationPreoperative pulmonary dysfunctionPrimary end pointSecondary end pointsCoronary artery bypassPerioperative myocardial infarctionArtery bypass graftOnly independent predictorHigh-volume centersAscending Aorta ReplacementCABG groupArtery bypassCoronary revascularizationPulmonary dysfunctionUnadjusted incidenceAdverse eventsPostoperative outcomes
2019
Effect of atrial pacing on post-operative atrial fibrillation following coronary artery bypass grafting: Pairwise and network meta-analyses
Ruan Y, Robinson NB, Naik A, Silva M, Hameed I, Rahouma M, Oakley C, Di Franco A, Zamvar V, Girardi LN, Gaudino M. Effect of atrial pacing on post-operative atrial fibrillation following coronary artery bypass grafting: Pairwise and network meta-analyses. International Journal Of Cardiology 2019, 302: 103-107. PMID: 31837901, DOI: 10.1016/j.ijcard.2019.12.009.Peer-Reviewed Original ResearchConceptsPost-operative atrial fibrillationCoronary artery bypassBiA pacingAtrial pacingArtery bypassSecondary outcomesAtrial fibrillationIncidence of POAFGeneric inverse variance methodRight atrial pacingInverse variance methodLargest risk reductionSystematic literature searchPOAF incidenceOperative mortalityPostoperative bleedingPrimary outcomePacing modalitiesClinical trialsLower incidencePacingLiterature searchIncidenceFibrillationRisk reduction