2021
Effects of Experimental Interventions to Improve the Biomedical Peer‐Review Process: A Systematic Review and Meta‐Analysis
Gaudino M, Robinson NB, Di Franco A, Hameed I, Naik A, Demetres M, Girardi LN, Frati G, Fremes SE, Biondi‐Zoccai G. Effects of Experimental Interventions to Improve the Biomedical Peer‐Review Process: A Systematic Review and Meta‐Analysis. Journal Of The American Heart Association 2021, 10: e019903. PMID: 34278828, PMCID: PMC8475712, DOI: 10.1161/jaha.120.019903.Peer-Reviewed Original ResearchConceptsStandardized mean differenceRandomized trialsEffects of interventionsPeer review interventionMean changeMAIN OUTCOMESmall studySystematic reviewMeta-AnalysisMean differenceLonger durationExperimental interventionInterventionIndividual studiesTrialsFurther studiesImproved qualityDurationConclusion ModificationReview qualitySignificant improvementPeer review processBackground qualityCharacteristics of Randomized Clinical Trials in Surgery From 2008 to 2020
Robinson NB, Fremes S, Hameed I, Rahouma M, Weidenmann V, Demetres M, Morsi M, Soletti G, Di Franco A, Zenati MA, Raja SG, Moher D, Bakaeen F, Chikwe J, Bhatt DL, Kurlansky P, Girardi LN, Gaudino M. Characteristics of Randomized Clinical Trials in Surgery From 2008 to 2020. JAMA Network Open 2021, 4: e2114494. PMID: 34190996, PMCID: PMC8246313, DOI: 10.1001/jamanetworkopen.2021.14494.Peer-Reviewed Original ResearchConceptsMost trialsClinical eventsSurgical interventionSurgical RCTsClinical trialsSurgeon experienceMinor clinical eventsMore surgical interventionsReporting biasMajor clinical eventsRandomized clinical trialsRisk of biasMedian fragility indexMedian sample sizeLarge treatment effectsPrimary outcomeTRIAL REGISTRATIONControl armTrial characteristicsSurgical trialsHigh riskSuperiority designConcerns of biasPrimary analysisRCTs
2020
Overall and Cause-Specific Mortality in Randomized Clinical Trials Comparing Percutaneous Interventions With Coronary Bypass Surgery
Gaudino M, Hameed I, Farkouh ME, Rahouma M, Naik A, Robinson NB, Ruan Y, Demetres M, Biondi-Zoccai G, Angiolillo DJ, Bagiella E, Charlson ME, Benedetto U, Ruel M, Taggart DP, Girardi LN, Bhatt DL, Fremes SE. Overall and Cause-Specific Mortality in Randomized Clinical Trials Comparing Percutaneous Interventions With Coronary Bypass Surgery. JAMA Internal Medicine 2020, 180: 1638-1646. PMID: 33044497, PMCID: PMC7551235, DOI: 10.1001/jamainternmed.2020.4748.Peer-Reviewed Original ResearchConceptsPercutaneous coronary interventionRandomized clinical trialsCause-specific mortalityCoronary artery diseaseBare metal stentsNoncardiac mortalityCause mortalityCoronary interventionArtery diseaseClinical trialsTrials of PCIEnd pointLeft main diseaseCoronary artery bypassStudy end pointCoronary bypass surgeryData extractionTreatment of patientsCochrane Library databasesPreferred Reporting ItemsRandom-effects modelArtery bypassCardiac mortalityRevascularization TrialBypass surgeryImpact of Operator Characteristics on Outcomes in Transcatheter Aortic Valve Replacement
Rong LQ, Gaudino M, Tam D, Mao J, Zheng X, Hameed I, Khan F, Salemi A, Sedrakyan A, Neuburger PJ, Fremes S. Impact of Operator Characteristics on Outcomes in Transcatheter Aortic Valve Replacement. The Annals Of Thoracic Surgery 2020, 111: 853-860. PMID: 32795521, DOI: 10.1016/j.athoracsur.2020.06.018.Peer-Reviewed Original ResearchConceptsTranscatheter aortic valve replacementTranscatheter aortic valve replacement (TAVR) proceduresAortic valve replacement proceduresAortic valve replacementAcute myocardial infarctionHealth Statewide PlanningValve replacement proceduresOperator characteristicsInhospital outcomesTAVR volumeInhospital mortalityValve replacementPrimary outcomeMyocardial infarctionSubgroup analysisStatewide PlanningProvider characteristicsCardiology practiceNew York State DepartmentInterventional cardiologyTAVROperator specialtyReplacement proceduresMedical school locationSignificant differencesPublication of cardiac surgery research papers in top cardiovascular journals
Gaudino M, Morsi M, Hameed I, Naik A, Robinson NB, Benedetto U, Ruel M. Publication of cardiac surgery research papers in top cardiovascular journals. Journal Of Cardiac Surgery 2020, 35: 2734-2736. PMID: 33043662, DOI: 10.1111/jocs.14894.Peer-Reviewed Original ResearchMeSH KeywordsBibliographies as TopicCardiologyHumansPeriodicals as TopicPublicationsResearchSocieties, MedicalTime FactorsAssociation of Radial Artery Graft vs Saphenous Vein Graft With Long-term Cardiovascular Outcomes Among Patients Undergoing Coronary Artery Bypass Grafting
Gaudino M, Benedetto U, Fremes S, Ballman K, Biondi-Zoccai G, Sedrakyan A, Nasso G, Raman J, Buxton B, Hayward PA, Moat N, Collins P, Webb C, Peric M, Petrovic I, Yoo KJ, Hameed I, Di Franco A, Moscarelli M, Speziale G, Puskas JD, Girardi LN, Hare DL, Taggart DP. Association of Radial Artery Graft vs Saphenous Vein Graft With Long-term Cardiovascular Outcomes Among Patients Undergoing Coronary Artery Bypass Grafting. JAMA 2020, 324: 179-187. PMID: 32662861, PMCID: PMC7361649, DOI: 10.1001/jama.2020.8228.Peer-Reviewed Original ResearchConceptsCoronary artery bypassSaphenous vein graftsComposite of deathRadial artery graftArtery bypassVein graftsRadial arteryMyocardial infarctionArtery graftCardiovascular outcomesClinical outcomesSaphenous veinLong-term cardiovascular outcomesPatient-level pooled analysisCoronary Artery Bypass GraftingArtery Bypass GraftingIndividual participant dataBypass GraftingAdult patientsComposite outcomeSecondary outcomesPrimary outcomeRandomized trialsPooled analysisObservational studySpinal cord injury after open and endovascular repair of descending thoracic and thoracoabdominal aortic aneurysms: A meta-analysis
Gaudino M, Khan FM, Rahouma M, Naik A, Hameed I, Spadaccio C, Robinson NB, Ruan Y, Demetres M, Oakley CT, Gambardella I, Iannacone EM, Lau C, Girardi LN. Spinal cord injury after open and endovascular repair of descending thoracic and thoracoabdominal aortic aneurysms: A meta-analysis. Journal Of Thoracic And Cardiovascular Surgery 2020, 163: 552-564. PMID: 32561196, DOI: 10.1016/j.jtcvs.2020.04.126.Peer-Reviewed Original ResearchConceptsThoracoabdominal aortic aneurysmsPooled rateTAAA repairOperative mortalityEndovascular repairAneurysm repairAortic aneurysmSpinal cord injury ratesGeneric inverse variance methodCrawford extent ILong-term mortalityEndovascular aneurysm repairSpinal cord injuryInverse variance methodDrain-related complicationsSystematic literature searchPostoperative strokeLate mortalitySecondary outcomesOpen repairPrimary outcomeRelated complicationsThoracic aneurysmCord injuryInjury rates
2019
Characteristics and anatomic distribution of early vs late stroke after cardiac surgery
Ivascu NS, Khan FM, Rahouma M, Hameed I, Abouarab A, Segal AZ, Gaudino MFL, Girardi LN. Characteristics and anatomic distribution of early vs late stroke after cardiac surgery. Journal Of Cardiac Surgery 2019, 34: 684-689. PMID: 31212394, DOI: 10.1111/jocs.14121.Peer-Reviewed Original ResearchConceptsLate strokeOperative mortalityCardiac surgeryEarly strokePerioperative strokeOpen cardiac surgeryTime of presentationOpen heart surgeryImpact of strokeWeill Cornell MedicinePerioperative variablesAdult patientsAnterior circulationEmbolic eventsSecondary outcomesCardiopulmonary bypassLikely etiologyAnatomic distributionHeart surgeryRisk factorsAnatomic locationHigh incidencePatientsSurgeryStrokeSinus of Valsalva aneurysm repairs: Operative technique and lessons learned
Wingo M, de Angelis P, Worku BM, Leonard JR, Khan FM, Hameed I, Lau C, Gaudino M, Girardi LN. Sinus of Valsalva aneurysm repairs: Operative technique and lessons learned. Journal Of Cardiac Surgery 2019, 34: 400-403. PMID: 30953447, DOI: 10.1111/jocs.14041.Peer-Reviewed Original ResearchConceptsSOV aneurysmAneurysm repairSingle tertiary referral centerRight ventricular outflow tractPulmonary artery compressionValsalva aneurysm repairYears underwent repairTertiary referral centerVentricular outflow tractBentall procedureArtery compressionOperative interventionPostoperative periodReferral centerValsalva aneurysmUnderwent repairOperative managementPrimary aneurysmMean ageMyocardial infarctionAneurysm diameterOutflow tractOperative techniqueAneurysm recurrenceSafe option