2023
A Systematic Review of Contemporary Randomized Trials in Cardiothoracic Surgery
Robinson N, Rahouma M, Audisio K, Cancelli G, Demetres M, Soletti G, Hameed I, Girardi L, Ruel M, Fremes S, Gaudino M. A Systematic Review of Contemporary Randomized Trials in Cardiothoracic Surgery. Annals Of Thoracic Surgery Short Reports 2023, 1: 537-541. DOI: 10.1016/j.atssr.2023.05.017.Peer-Reviewed Original ResearchCardiothoracic surgeryMost trialsPrimary outcomePrimary end pointComposite primary outcomeMajor clinical eventsMedian fragility indexEligible trialsRandomized trialsTrial armsClinical eventsContemporary trialsFavorable outcomePatient outcomesTrial characteristicsMedian numberSurgeon experienceResults NinetyGeneral surgeryHigh riskSuperiority designSurgerySystematic reviewEnd pointTrials
2021
Effects of Experimental Interventions to Improve the Biomedical Peer‐Review Process: A Systematic Review and Meta‐Analysis
Gaudino M, Robinson NB, Di Franco A, Hameed I, Naik A, Demetres M, Girardi LN, Frati G, Fremes SE, Biondi‐Zoccai G. Effects of Experimental Interventions to Improve the Biomedical Peer‐Review Process: A Systematic Review and Meta‐Analysis. Journal Of The American Heart Association 2021, 10: e019903. PMID: 34278828, PMCID: PMC8475712, DOI: 10.1161/jaha.120.019903.Peer-Reviewed Original ResearchConceptsStandardized mean differenceRandomized trialsEffects of interventionsPeer review interventionMean changeMAIN OUTCOMESmall studySystematic reviewMeta-AnalysisMean differenceLonger durationExperimental interventionInterventionIndividual studiesTrialsFurther studiesImproved qualityDurationConclusion ModificationReview qualitySignificant improvementPeer review processBackground qualityAngiographic Patency of Coronary Artery Bypass Conduits: A Network Meta‐Analysis of Randomized Trials
Gaudino M, Hameed I, Robinson NB, Ruan Y, Rahouma M, Naik A, Weidenmann V, Demetres M, Tam D, Hare DL, Girardi LN, Biondi‐Zoccai G, Fremes S. Angiographic Patency of Coronary Artery Bypass Conduits: A Network Meta‐Analysis of Randomized Trials. Journal Of The American Heart Association 2021, 10: e019206. PMID: 33686866, PMCID: PMC8174193, DOI: 10.1161/jaha.120.019206.Peer-Reviewed Original ResearchConceptsCoronary artery bypass conduitsTouch saphenous veinAngiographic patency ratesRadial arterySaphenous veinPatency ratesGraft occlusionRandomized trialsBypass conduitRight internal thoracic arteryTouch saphenous vein graftsCoronary bypass surgerySaphenous vein graftsGraft occlusion rateInternal thoracic arteryBest conduitNetwork Meta-AnalysisSystematic literature searchGastroepiploic arteryBypass surgeryPrimary outcomeThoracic arteryAngiographic patencyVein graftsOcclusion rate
2020
Association of Radial Artery Graft vs Saphenous Vein Graft With Long-term Cardiovascular Outcomes Among Patients Undergoing Coronary Artery Bypass Grafting
Gaudino M, Benedetto U, Fremes S, Ballman K, Biondi-Zoccai G, Sedrakyan A, Nasso G, Raman J, Buxton B, Hayward PA, Moat N, Collins P, Webb C, Peric M, Petrovic I, Yoo KJ, Hameed I, Di Franco A, Moscarelli M, Speziale G, Puskas JD, Girardi LN, Hare DL, Taggart DP. Association of Radial Artery Graft vs Saphenous Vein Graft With Long-term Cardiovascular Outcomes Among Patients Undergoing Coronary Artery Bypass Grafting. JAMA 2020, 324: 179-187. PMID: 32662861, PMCID: PMC7361649, DOI: 10.1001/jama.2020.8228.Peer-Reviewed Original ResearchConceptsCoronary artery bypassSaphenous vein graftsComposite of deathRadial artery graftArtery bypassVein graftsRadial arteryMyocardial infarctionArtery graftCardiovascular outcomesClinical outcomesSaphenous veinLong-term cardiovascular outcomesPatient-level pooled analysisCoronary Artery Bypass GraftingArtery Bypass GraftingIndividual participant dataBypass GraftingAdult patientsComposite outcomeSecondary outcomesPrimary outcomeRandomized trialsPooled analysisObservational study