Robustness of the Comparative Observational Evidence Supporting Class I and II Cardiac Surgery Procedures
Gaudino M, Hameed I, Robinson NB, Naik A, Weidenmann V, Ruan Y, Tam D, Girardi LN, Fremes S. Robustness of the Comparative Observational Evidence Supporting Class I and II Cardiac Surgery Procedures. Journal Of The American Heart Association 2020, 9: e016964. PMID: 32815427, PMCID: PMC7660761, DOI: 10.1161/jaha.120.016964.Peer-Reviewed Original ResearchConceptsBilateral internal thoracic arteryValve-sparing root replacementSingle internal thoracic arteryInternal thoracic arteryThoracic arteryBentall procedureRoot replacementMV repairObservational studyClass IEffect estimatesCardiac surgery proceduresImproved clinical outcomesMitral valve repairUnmeasured confoundingEffect sizeObserved effect estimatesMV replacementSurgery guidelinesClinical outcomesValve repairRisk ratioArterySurgery proceduresObserved associationsAssociation of Radial Artery Graft vs Saphenous Vein Graft With Long-term Cardiovascular Outcomes Among Patients Undergoing Coronary Artery Bypass Grafting
Gaudino M, Benedetto U, Fremes S, Ballman K, Biondi-Zoccai G, Sedrakyan A, Nasso G, Raman J, Buxton B, Hayward PA, Moat N, Collins P, Webb C, Peric M, Petrovic I, Yoo KJ, Hameed I, Di Franco A, Moscarelli M, Speziale G, Puskas JD, Girardi LN, Hare DL, Taggart DP. Association of Radial Artery Graft vs Saphenous Vein Graft With Long-term Cardiovascular Outcomes Among Patients Undergoing Coronary Artery Bypass Grafting. JAMA 2020, 324: 179-187. PMID: 32662861, PMCID: PMC7361649, DOI: 10.1001/jama.2020.8228.Peer-Reviewed Original ResearchConceptsCoronary artery bypassSaphenous vein graftsComposite of deathRadial artery graftArtery bypassVein graftsRadial arteryMyocardial infarctionArtery graftCardiovascular outcomesClinical outcomesSaphenous veinLong-term cardiovascular outcomesPatient-level pooled analysisCoronary Artery Bypass GraftingArtery Bypass GraftingIndividual participant dataBypass GraftingAdult patientsComposite outcomeSecondary outcomesPrimary outcomeRandomized trialsPooled analysisObservational study