1980
The Influence of Hormones on the Biochemical Development of Fetal Rat Lung in Organ Culture. II. Insulin
Gross I, Walker Smith G, Wilson C, Maniscalco W, Ingleson L, Brehier A, Rooney S. The Influence of Hormones on the Biochemical Development of Fetal Rat Lung in Organ Culture. II. Insulin. Pediatric Research 1980, 14: 834-838. PMID: 6995921, DOI: 10.1203/00006450-198006000-00012.Peer-Reviewed Original ResearchConceptsFetal rat lungRat lungCholine incorporationSignificant decreasePhospholipid fractionInfluence of insulinEffect of insulinInfluence of hormonesPercentage of radioactivityType II cellsLung cell growthLung cell differentiationLung maturationOrgan culture systemInsulin treatmentMorphologic evidencePhospholipid radioactivityInsulinMorphologic maturationSurfactant phospholipidsGlycogen contentII cellsOrgan cultureBiochemical developmentLamellar bodies
1979
Effects of betamethasone on phospholipid content, composition and biosynthesis in the fetal rabbit lung
Rooney S, Gobran L, Marino P, Maniscalco W, Gross I. Effects of betamethasone on phospholipid content, composition and biosynthesis in the fetal rabbit lung. Biochimica Et Biophysica Acta 1979, 572: 64-76. PMID: 216408, DOI: 10.1016/0005-2760(79)90200-5.Peer-Reviewed Original ResearchConceptsLung lavageFetal lung lavageFetal lung slicesAdministration of betamethasoneEffect of betamethasoneFetal lung maturationFetal rabbit lungPhosphatidylcholine/sphingomyelin ratioLung glycogenBetamethasone administrationLung maturationPregnant rabbitsDays gestationFetal lungLung slicesRabbit lungsStress-induced accelerationDirect administrationSphingomyelin ratioSurfactant phospholipidsBetamethasoneAdministrationRate of incorporationSurfactant productionLavage