2019
Discovery of Noncancer Drug Effects on Survival in Electronic Health Records of Patients With Cancer: A New Paradigm for Drug Repurposing
Wu Y, Warner J, Wang L, Jiang M, Xu J, Chen Q, Nian H, Dai Q, Du X, Yang P, Denny J, Liu H, Xu H. Discovery of Noncancer Drug Effects on Survival in Electronic Health Records of Patients With Cancer: A New Paradigm for Drug Repurposing. JCO Clinical Cancer Informatics 2019, 3: cci.19.00001. PMID: 31141421, PMCID: PMC6693869, DOI: 10.1200/cci.19.00001.Peer-Reviewed Original ResearchConceptsVanderbilt University Medical CenterCancer survivalMayo ClinicDrug repurposingNoncancer drugsElectronic health record dataCancer registry dataEHR dataClinical trial evaluationOverall cancer survivalUniversity Medical CenterHealth record dataElectronic health recordsTreatment of cancerClinical trialsDrug classesRegistry dataMedical CenterDrug effectsSignificant associationLongitudinal EHRNew indicationsPatientsCancerHealth records
2017
Psychiatric symptom recognition without labeled data using distributional representations of phrases and on-line knowledge
Zhang Y, Zhang O, Wu Y, Lee H, Xu J, Xu H, Roberts K. Psychiatric symptom recognition without labeled data using distributional representations of phrases and on-line knowledge. Journal Of Biomedical Informatics 2017, 75: s129-s137. PMID: 28624644, PMCID: PMC5705397, DOI: 10.1016/j.jbi.2017.06.014.Peer-Reviewed Original ResearchConceptsPsychiatric symptomsCandidate symptomMental disordersPsychiatric notesList of symptomsMayo ClinicClinical dataSymptom recognitionPatient experiencePersonalized preventionSymptomsAmerican Psychiatric AssociationAbstractTextClinical conceptsPsychiatric AssociationPhenotypic classificationDisordersClinical textMIMIC-IIHealthcare knowledgeConclusionSubjective descriptionsClinicDiseaseDiagnosis