2019
Frozen versus fresh single blastocyst transfer in ovulatory women: a multicentre, randomised controlled trial
Wei D, Liu J, Sun Y, Shi Y, Zhang B, Liu J, Tan J, Liang X, Cao Y, Wang Z, Qin Y, Zhao H, Zhou Y, Ren H, Hao G, Ling X, Zhao J, Zhang Y, Qi X, Zhang L, Deng X, Chen X, Zhu Y, Wang X, Tian L, Lv Q, Ma X, Zhang H, Legro R, Chen Z. Frozen versus fresh single blastocyst transfer in ovulatory women: a multicentre, randomised controlled trial. The Lancet 2019, 393: 1310-1318. PMID: 30827784, DOI: 10.1016/s0140-6736(18)32843-5.Peer-Reviewed Original ResearchConceptsFrozen single blastocyst transferFresh single blastocyst transferSingle blastocyst transferElective single embryo transferRisk of pre-eclampsiaFrozen blastocyst transferBlastocyst transferLivebirth rateSevere ovarian hyperstimulation syndromePre-eclampsiaOvulatory womenPregnancy rateEmbryo transferOvarian hyperstimulation syndromeAcademic fertility centreFrozen-thawed single blastocyst transferHigher risk of pre-eclampsiaIn vitro fertilisationIncreased risk of pre-eclampsiaFrozen embryo transferExtended embryo cultureSingle embryo transferFertility centreHyperstimulation syndromeLower pregnancy rate
2018
Polycystic ovary syndrome and autism: A test of the prenatal sex steroid theory
Cherskov A, Pohl A, Allison C, Zhang H, Payne RA, Baron-Cohen S. Polycystic ovary syndrome and autism: A test of the prenatal sex steroid theory. Translational Psychiatry 2018, 8: 136. PMID: 30065244, PMCID: PMC6068102, DOI: 10.1038/s41398-018-0186-7.Peer-Reviewed Original ResearchConceptsPolycystic ovary syndromeClinical Practice Research DatalinkOvary syndromeOdds ratioPrevalence of PCOSRisk of PCOSMaternal metabolic conditionsMaternal psychiatric diagnosisChildren of womenCase-control studyPrenatal testosteroneRisk of autismElectronic health recordsObstetric complicationsSex steroidsPsychiatric diagnosisGreater riskMetabolic conditionsElevated levelsHealth recordsWomenSyndromeChildrenRiskTestosterone
2017
Effect of Preconception Impaired Glucose Tolerance on Pregnancy Outcomes in Women With Polycystic Ovary Syndrome
Wei D, Zhang B, Shi Y, Zhang L, Zhao S, Du Y, Xu L, Legro RS, Zhang H, Chen ZJ. Effect of Preconception Impaired Glucose Tolerance on Pregnancy Outcomes in Women With Polycystic Ovary Syndrome. The Journal Of Clinical Endocrinology & Metabolism 2017, 102: 3822-3829. PMID: 28938429, DOI: 10.1210/jc.2017-01294.Peer-Reviewed Original ResearchConceptsOral glucose tolerance testPolycystic ovary syndromePregnancy outcomesI-IFGOvary syndromeGlucose toleranceHigh riskIntrinsic insulin resistanceAdverse pregnancy outcomesTotal testosterone levelsDuration of infertilityImpaired glucose tolerancePregnancy loss rateBody mass indexFrozen embryo transferGlucose tolerance testMain outcome measuresGestational diabetesObstetric complicationsSingleton newbornsSingleton pregnanciesGestational ageMass indexTwin pregnanciesInsulin levels
2015
Impact of Male and Female Weight, Smoking, and Intercourse Frequency on Live Birth in Women With Polycystic Ovary Syndrome
Polotsky AJ, Allshouse AA, Casson PR, Coutifaris C, Diamond MP, Christman GM, Schlaff WD, Alvero R, Trussell JC, Krawetz SA, Santoro N, Eisenberg E, Zhang H, Legro RS. Impact of Male and Female Weight, Smoking, and Intercourse Frequency on Live Birth in Women With Polycystic Ovary Syndrome. The Journal Of Clinical Endocrinology & Metabolism 2015, 100: 2405-2412. PMID: 25856211, PMCID: PMC4454812, DOI: 10.1210/jc.2015-1178.Peer-Reviewed Original ResearchConceptsPolycystic ovary syndromeBody mass indexFemale body mass indexMale body mass indexLive birthsOvary syndromeFertility treatment successSexual intercourse attemptsLower chanceNormal semen parametersClomiphene citrateIntercourse attemptsII trialObese menObese womenInfertile womenMale obesityMass indexRegular intercourseProspective dataMale factorTreatment successMale smokingLarge cohortIntercourse frequency
2012
Endometrial Shedding Effect on Conception and Live Birth in Women With Polycystic Ovary Syndrome
Diamond MP, Kruger M, Santoro N, Zhang H, Casson P, Schlaff W, Coutifaris C, Brzyski R, Christman G, Carr BR, McGovern PG, Cataldo NA, Steinkampf MP, Gosman GG, Nestler JE, Carson S, Myers EE, Eisenberg E, Legro RS. Endometrial Shedding Effect on Conception and Live Birth in Women With Polycystic Ovary Syndrome. Obstetrics And Gynecology 2012, 119: 902-908. PMID: 22525900, PMCID: PMC4007263, DOI: 10.1097/aog.0b013e31824da35c.Peer-Reviewed Original ResearchConceptsPolycystic ovary syndromeLive birth rateAnovulatory cyclesEndometrial sheddingClomiphene citrateOvary syndromeLive birthsEunice Kennedy Shriver National InstituteBirth rateCommon clinical practiceOccurrence of ovulationRate of conceptionAnovulatory womenOvarian stimulationOvulation inductionSpontaneous mensesProgestin withdrawalChild healthClinical practiceNetwork trialSecondary analysisOvulation rateMetforminAdverse effectsWomen
1999
Analysis of Infant Growth Curves Using Multivariate Adaptive Splines
Zhang H. Analysis of Infant Growth Curves Using Multivariate Adaptive Splines. Biometrics 1999, 55: 452-459. PMID: 11318199, DOI: 10.1111/j.0006-341x.1999.00452.x.Peer-Reviewed Original Research