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INFORMATION FOR

    Henry J. Binder, MD

    Professor Emeritus of Medicine (Digestive Diseases)
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    Contact Info

    henry.binder@yale.edu
    203.785.4796

    Yale School of Medicine

    Department of Medicine (Digestive Diseases), PO Box 208019

    New Haven, CT 06520-8019

    United States

    About

    Titles

    Professor Emeritus of Medicine (Digestive Diseases)

    Appointments

    Other Departments & Organizations

    Education & Training

    Postdoctoral Fellow
    Yale University School of Medicine (1965)
    Intern/Resident
    Bellevue Hospital, New York University (1963)
    MD
    New York University (1961)
    BA
    Dartmouth College (1957)

    Research

    Overview

    Dr. Binder's research career has primarily been directed toward the regulation of colonic electrolyte transport and the pathophysiology of diarrhea and the basis for development of new approaches for treatment of diarrhea. These transport studies were primarily in vitro and dissected the cellular mechanisms of Na, C1, K, HCO3 and short-chain fatty acid transport and were supported by NIDDK for 37 years. During the past few years, Dr. Binder has focused his investigative activities toward the establishment of a major modification of oral rehydration solution (ORS) that is based on his prior laboratory studies that demonstrated butyrate-stimulated Na absorption in the colon was cyclic AMP-insensitive. These studies supported by Bill & Melinda Gates Foundation are designed to increase the uptake of ORS with the adaption of an improved formulation with resistant starch (starch that is relatively insensitive to amylase digestion).

    Medical Research Interests

    Adenosine Triphosphatases; Digestive System Diseases; Epithelial Cells; Fatty Acids, Volatile; Ion Transport

    Research at a Glance

    Yale Co-Authors

    Frequent collaborators of Henry J. Binder's published research.

    Publications

    2014

    2013

    2012

    2011

    2010

    2009

    • Organization of the gastrointestinal system
      Binder, H.J.: Organization of the gastrointestinal system. In: Medical Physiology. Edited by Boron, E., and Boulapaep, E.L., Saunders, Philadelphia, 2nd ed. pp 883-894, 2009.
      Peer-Reviewed Original Research
    • Gastric Function
      Binder, H.J.: Gastric Function. In: Medical Physiology. Edited by Boron, E., and Boulapaep, E.L., Saunders, Philadelphia, 2nd ed. pp 895-911, 2009.
      Peer-Reviewed Original Research
    • Nutrient digestion and absorption
      Binder, H.J.: Nutrient digestion and absorption. In: Medical Physiology. Edited by Boron, E., and Boulapaep, E.L., Saunders, Philadelphia, 2nd ed. pp 949-979, 2009.
      Peer-Reviewed Original Research
    • Intestinal fluid and electrolyte movement
      Binder. H.J.: Intestinal fluid and electrolyte movement. In: Medical Physiology. Edited by Boron, E., and Boulapaep, E.L., Saunders, Philadelphia, 2nd ed. pp 933-948, 2009.
      Peer-Reviewed Original Research
    See All Publications

    Academic Achievements & Community Involvement

    • activity

      Diarrhea and Oral Rehydration Therapy

      Research

    Get In Touch

    Contacts

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    Academic Office Number
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    Mailing Address

    Yale School of Medicine

    Department of Medicine (Digestive Diseases), PO Box 208019

    New Haven, CT 06520-8019

    United States

    Administrative Support