2023
Alcohol-mediated renal denervation in patients with hypertension in the absence of antihypertensive medications.
Pathak A, Rudolph U, Saxena M, Zeller T, Müller-Ehmsen J, Lipsic E, Schmieder R, Sievert H, Halbach M, Sharif F, Parise H, Fischell T, Weber M, Kandzari D, Mahfoud F. Alcohol-mediated renal denervation in patients with hypertension in the absence of antihypertensive medications. EuroIntervention 2023, 19: 602-611. PMID: 37427416, PMCID: PMC10493775, DOI: 10.4244/eij-d-23-00088.Peer-Reviewed Original ResearchConceptsSystolic blood pressureRenal denervationBlood pressureAntihypertensive medicationsRDN groupMedication burdenMean office blood pressureOffice systolic blood pressureSystolic BP 140Office blood pressurePrimary efficacy endpointMajor adverse eventsSystolic BP changeDiastolic blood pressureLower blood pressureRadiofrequency renal denervationLower medication burdenSignificant BP differencesMedication escalationEfficacy endpointSafety endpointAdverse eventsSham groupBP changesMedication washout
2007
Associations of Plasma Natriuretic Peptide, Adrenomedullin, and Homocysteine Levels With Alterations in Arterial Stiffness
Levy D, Hwang S, Kayalar A, Benjamin E, Vasan R, Parise H, Larson M, Wang T, Selhub J, Jacques P, Vita J, Keyes M, Mitchell G. Associations of Plasma Natriuretic Peptide, Adrenomedullin, and Homocysteine Levels With Alterations in Arterial Stiffness. Circulation 2007, 115: 3079-3085. PMID: 17533184, DOI: 10.1161/circulationaha.106.652842.Peer-Reviewed Original ResearchConceptsN-terminal atrial natriuretic peptideCarotid-femoral pulse wave velocityB-type natriuretic peptidePulse wave velocityAtrial natriuretic peptideCarotid-radial pulse wave velocityCentral pulse pressurePlasma natriuretic peptidesNatriuretic peptideArterial stiffnessHomocysteine levelsPulse pressureFramingham Heart StudyHeart StudyPlasma N-terminal atrial natriuretic peptideDiastolic blood pressureMean arterial pressureCarotid pulse pressureArterial wall stiffnessForward pressure waveArterial pressureCentral systolicBlood pressureHomocysteine concentrationsCardiovascular disease