2024
The mammary hair of Monodelphis domestica and homology of the mammary pilosebacous unit
Stadtmauer D, Wagner G. The mammary hair of Monodelphis domestica and homology of the mammary pilosebacous unit. Journal Of Morphology 2024, 285: e21769. PMID: 39188032, DOI: 10.1002/jmor.21769.Peer-Reviewed Original Research
2022
The hierarchical basis of serial homology and evolutionary novelty
DiFrisco J, Love A, Wagner G. The hierarchical basis of serial homology and evolutionary novelty. Journal Of Morphology 2022, 284: e21531. PMID: 36317664, DOI: 10.1002/jmor.21531.Peer-Reviewed Original ResearchConceptsSerial homologyWing serial homologsTree of lifeExtent of homologyParalogous genesEvolutionary noveltyPhylogenetic historyPhylogenetic conceptsGene sequencesSerial homologsEvolutionary precursorPhylogenetic interpretationMost biologistsHomologyCell typesBiological phenomenaGenetic contributionEpidermal appendagesWidespread overlapGenesNew charactersHomologLineagesAppendagesFecundity
2020
Character identity mechanisms: a conceptual model for comparative-mechanistic biology
DiFrisco J, Love A, Wagner G. Character identity mechanisms: a conceptual model for comparative-mechanistic biology. Biology & Philosophy 2020, 35: 44. DOI: 10.1007/s10539-020-09762-2.Peer-Reviewed Original Research
2015
Homology in the Age of Developmental Genomics
Wagner G. Homology in the Age of Developmental Genomics. 2015, 25-43. DOI: 10.1007/978-3-7091-1862-7_2.Peer-Reviewed Original ResearchModel organismsEvolutionary biologyHomology conceptRecent common ancestorDevelopmental genomicsPhylogenetic relationshipsCommon ancestorDarwinian traditionHomologySame organOrganismsSpeciesComparative anatomyDifferent animalsBiologistsBiologyFundamental roleRichard OwenImportant roleGenomicsAncestorGenesOrgansHumansRole
2014
Reinventing the Organism: Evolvability and Homology in Post-Dahlem Evolutionary Biology
Wagner G. Reinventing the Organism: Evolvability and Homology in Post-Dahlem Evolutionary Biology. Boston Studies In The Philosophy And History Of Science 2014, 307: 327-342. DOI: 10.1007/978-94-017-9412-1_15.Peer-Reviewed Original ResearchEvolutionary biologyDahlem ConferenceGenotype-phenotype mapStructure of organismsLimited pleiotropyNatural selectionEvolutionary causationPhenotype evolutionOrganism conceptRandom mutationsHomologyOrganismsEvolvabilityBiologyDevelopmental structuresMutationsDevelopmental organizationPleiotropySeedsFitnessSelectionAdaptation
2007
The developmental genetics of homology
Wagner GP. The developmental genetics of homology. Nature Reviews Genetics 2007, 8: 473-479. PMID: 17486120, DOI: 10.1038/nrg2099.Peer-Reviewed Original Research
2001
The tetrapod limb: A hypothesis on its origin
Wagner G, Chiu C. The tetrapod limb: A hypothesis on its origin. Journal Of Experimental Zoology 2001, 291: 226-240. PMID: 11598912, DOI: 10.1002/jez.1100.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsTetrapod limbsExpression domainsHoxa-13Hoxa-11Fin-limb transitionExclusive expression domainsMajor morphological adaptationsProximal-distal axisVertebrate evolutionFin developmentHoxa-11 expressionTerrestrial lifestyleFin skeletonMorphological adaptationsDevelopmental mechanismsExpression patternsLimb budPaleontological evidenceGenetic hypothesisExpressionZebrafishEvolutionHomologyAquaticGenes
2000
Developmental Evolution as a Mechanistic Science: The Inference from Developmental Mechanisms to Evolutionary Processes1
Wagner G, Chiu C, Laubichler M. Developmental Evolution as a Mechanistic Science: The Inference from Developmental Mechanisms to Evolutionary Processes1. Integrative And Comparative Biology 2000, 40: 819-831. DOI: 10.1668/0003-1569(2000)040[0819:deaams]2.0.co;2.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsDevelopmental evolutionEvolutionary innovationDevelopmental mechanismsFunction of genesEvolutionary geneticsGenetic architectureEvolutionary originEvolutionary biologyAssessment of homologyDevelopmental dynamicsSpecies differencesBiologyGenetic factorsHomologyGenesMechanismGeneticsSpeciesEvolutionRoleElucidationOriginMechanistic scienceCharacterDevelopmental Evolution as a Mechanistic Science: The Inference from Developmental Mechanisms to Evolutionary Processes1
Wagner G, Chiu C, Laubichler M. Developmental Evolution as a Mechanistic Science: The Inference from Developmental Mechanisms to Evolutionary Processes1. Integrative And Comparative Biology 2000, 40: 819-831. DOI: 10.1093/icb/40.5.819.Peer-Reviewed Original ResearchDevelopmental evolutionEvolutionary innovationDevelopmental mechanismsFunction of genesEvolutionary geneticsGenetic architectureEvolutionary originEvolutionary biologyAssessment of homologyDevelopmental dynamicsSpecies differencesBiologyGenetic factorsHomologyGenesMechanismGeneticsSpeciesEvolutionRoleElucidationOriginMechanistic scienceCharacter
1996
Homology, Hox Genes, and Developmental Integration1
MÜLLER G, WAGNER G. Homology, Hox Genes, and Developmental Integration1. Integrative And Comparative Biology 1996, 36: 4-13. DOI: 10.1093/icb/36.1.4.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsEpigenetic contextMorphological charactersGene expression patternsConcept of homologyGenetic redundancyPhenotypic evolutionEvolutionary innovationGenetic integrationHox genesTetrapod limbsGene functionGenetic identityDevelopmental systemsExpression patternsStructural homologyGenetic encodingNovel homologueHomologyMorphological identityRegulatory systemDevelopmental interactionsMorphological evolutionHomologuesGenesEvolution
1993
How can a character be developmentally constrained despite variation in developmental pathways?
Wagner G, Misof B. How can a character be developmentally constrained despite variation in developmental pathways? Journal Of Evolutionary Biology 1993, 6: 449-455. DOI: 10.1046/j.1420-9101.1993.6030449.x.Commentaries, Editorials and LettersDevelopmental constraintsDevelopmental biologyDevelopmental pathwaysEvolutionary developmental biologyComparative developmental biologyDevelopmental variationBody planAdaptive pressuresConservative patternAdult variationFundamental riddleHomologyBiologyBiological basisConservationPathwayAnatomical featuresMorphological patternsHomologuesEarly perturbationsVariationPatternsEarly stagesAdult patternFunction
1986
The Systems Approach: An Interface Between Development and Population Genetic Aspects of Evolution
Wagner G. The Systems Approach: An Interface Between Development and Population Genetic Aspects of Evolution. Dahlem Workshop Report 1986, 149-165. DOI: 10.1007/978-3-642-70831-2_8.Commentaries, Editorials and LettersDevelopmental constraintsPopulation genetic aspectsQuantitative genetic theoryConcept of homologyOrganismic evolutionCharacter evolutionEvolutionary historyEvolutionary modificationsDevelopmental programGenetic theoryFunctional constraintsModern SynthesisMorphological conceptsGenetic aspectsKey eventsHomologyNatural systems