2024
The extension of mammalian pregnancy required taming inflammation: Independent evolution of extended placentation in the tammar wallaby
Dudley J, Renfree M, Wagner G, Griffith O. The extension of mammalian pregnancy required taming inflammation: Independent evolution of extended placentation in the tammar wallaby. Proceedings Of The National Academy Of Sciences Of The United States Of America 2024, 121: e2310047121. PMID: 39378090, PMCID: PMC11494332, DOI: 10.1073/pnas.2310047121.Peer-Reviewed Original ResearchConceptsLive-bearing mammalsTammar wallabyInflammatory reactionMode of reproductionCompare gene expression changesMaternal-fetal interactionsGene expression changesMarsupial taxaPeriod of placentationIndependent evolutionMammalian pregnancyMarsupial speciesEutheriansFat-tailed dunnartExpression changesInflammatory genesInflammationPlacentationWallabyEpitheliochorial placentation
2023
Experimental and phylogenetic evidence for correlated gene expression evolution in endometrial and skin fibroblasts
Dighe A, Maziarz J, Ibrahim-Hashim A, Gatenby R, Kshitiz, Levchenko A, Wagner G. Experimental and phylogenetic evidence for correlated gene expression evolution in endometrial and skin fibroblasts. IScience 2023, 27: 108593. PMID: 38174318, PMCID: PMC10762354, DOI: 10.1016/j.isci.2023.108593.Peer-Reviewed Original ResearchGene expression changesGene expression evolutionEndometrial stromal fibroblastsExpression evolutionExpression changesCell typesGene expressionSimilar gene expression changesSubstantial gene expression changesGene expression profilesSkin fibroblastsMultiple cell typesEvolutionary correlationPhylogenetic evidenceEvolutionary changeDermal skin fibroblastsMammalian speciesExpression profilesPlacental invasivenessComparative datasetCancer growthCultured skin fibroblastsStromal fibroblastsFibroblastsMouse strains