2021
Single-cell analysis of prostaglandin E2-induced human decidual cell in vitro differentiation: a minimal ancestral deciduogenic signal†
Stadtmauer DJ, Wagner G. Single-cell analysis of prostaglandin E2-induced human decidual cell in vitro differentiation: a minimal ancestral deciduogenic signal†. Biology Of Reproduction 2021, 106: 155-172. PMID: 34591094, PMCID: PMC8757638, DOI: 10.1093/biolre/ioab183.Peer-Reviewed Original ResearchMeSH KeywordsCell DifferentiationCell Line, TransformedCells, CulturedCyclic AMPCyclic AMP-Dependent Protein KinasesDeciduaDinoprostoneEndometriumFemaleFibroblastsGene ExpressionGenome-Wide Association StudyHumansMedroxyprogesterone AcetatePregnancyReceptors, Prostaglandin E, EP2 SubtypeSequence Analysis, RNASingle-Cell AnalysisConceptsPlacental mammalsCore gene regulatory networkCyclic AMP/protein kinase A (cAMP/PKA) pathwayProtein kinase A (PKA) pathwaySenescence-associated genesProgesterone-dependent activationGenome-wide studiesSingle-cell transcriptomicsGene regulatory networksProgesterone-dependent inductionMembrane-permeable cAMPKinase A PathwaySingle-cell analysisUse of PGE2Outgroup taxaCellular statesRegulatory networksPKA axisGene expressionDecidual genesPKA activationPGE2 receptor 2Progestin-dependent inductionA PathwayAdenylyl cyclase activationDevo-Evo of Cell Types
Wagner G. Devo-Evo of Cell Types. 2021, 511-528. DOI: 10.1007/978-3-319-32979-6_153.Peer-Reviewed Original ResearchEvolutionary developmental biologyCell typesDevelopmental biologyCore gene regulatory networkAncestral cell typeCell type identityTranscription factor proteinsGene regulatory networksGene treesGene duplicationEvolutionary descentRegulatory complexRegulatory networksPopulation of cellsMolecular mechanismsFactor proteinOrganisms increasesEvolutionary perspectiveLineagesBiologyType identityMajor current challengeSpecific setTreesGenes
2019
Devo-Evo of Cell Types
Wagner G. Devo-Evo of Cell Types. 2019, 1-18. DOI: 10.1007/978-3-319-33038-9_153-1.Peer-Reviewed Original ResearchEvolutionary developmental biologyCell typesDevelopmental biologyCore gene regulatory networkAncestral cell typeCell type identityTranscription factor proteinsGene regulatory networksGene treesGene duplicationEvolutionary descentRegulatory complexRegulatory networksPopulation of cellsMolecular mechanismsFactor proteinOrganisms increasesEvolutionary perspectiveLineagesBiologyType identityMajor current challengeSpecific setTreesGenes
2015
Evolutionary innovations and novelties: Let us get down to business!
Wagner G. Evolutionary innovations and novelties: Let us get down to business! Zoologischer Anzeiger 2015, 256: 75-81. DOI: 10.1016/j.jcz.2015.04.006.Peer-Reviewed Original ResearchCore gene regulatory networkGene regulatory networksRegulatory networksNovel body partsEvolutionary innovationEvolutionary developmental biologyCore regulatory networkBody part identityEvolutionary noveltyEvolutionary biologistsEvolutionary biologyDevelopmental biologyEvolutionary changeBiological processesCell typesImportant unanswered questionsBiologyCritical insightsGenomicsRecent advancesMechanistic aspectsGenesBiologistsUnanswered questionsBody parts