2008
The Impact of Episodic CD4 Cell Count-Guided Antiretroviral Therapy on Quality of Life
Burman WJ, Grund B, Roediger MP, Friedland G, Darbyshire J, Wu AW. The Impact of Episodic CD4 Cell Count-Guided Antiretroviral Therapy on Quality of Life. JAIDS Journal Of Acquired Immune Deficiency Syndromes 2008, 47: 185-193. PMID: 17971716, DOI: 10.1097/qai.0b013e31815acaa4.Peer-Reviewed Original ResearchConceptsQuality of lifeEpisodic antiretroviral therapyAntiretroviral therapyDisease progressionQoL assessmentTherapy groupInferior QOLMedian CD4 lymphocyte countContinuous therapy groupExcellent general healthCD4 cell countCD4 lymphocyte countCells/mm3HIV disease progressionCurrent healthAntiretroviral Therapy studyTherapy armMean followContinuous therapyLymphocyte countAnalog scaleQOL outcomesGeneral healthQOL instrumentsQoL comparisons
2005
The Role of Substance Abuse in HIV Disease Progression: Reconciling Differences from Laboratory and Epidemiologic Investigations
Kapadia F, Vlahov D, Donahoe RM, Friedland G. The Role of Substance Abuse in HIV Disease Progression: Reconciling Differences from Laboratory and Epidemiologic Investigations. Clinical Infectious Diseases 2005, 41: 1027-1034. PMID: 16142670, DOI: 10.1086/433175.Peer-Reviewed Original ResearchConceptsHIV disease progressionDisease progressionEpidemiologic investigationsHIV/AIDS epidemicUse of licitEpidemiological studiesSubstance abuseStudy designDrug abuseAIDS epidemicCareful evaluationReview of findingsProgressionIllicit drugsLaboratory-based studiesMethodological strengthsFindingsAbuseMixed results