2022
Natural history of bicuspid aortic valves and ascending aortic aneurysms: Aortic center experience
Bellaire CP, Tharakan SM, Roy J, Puskas JD, Di Luozzo G. Natural history of bicuspid aortic valves and ascending aortic aneurysms: Aortic center experience. Journal Of Cardiac Surgery 2022, 37: 2326-2335. PMID: 35535018, DOI: 10.1111/jocs.16597.Peer-Reviewed Original ResearchConceptsBicuspid aortic valveAdverse event ratesTAV patientsEntire cohortAortic aneurysmAortic valveComputerized tomographyLow adverse event ratesOverall adverse event rateNatural historyEvent ratesTricuspid aortic valve patientsValve typeRoutine computerized tomographyMore CT scansAortic valve patientsCoronary artery diseaseMean aneurysm sizeAneurysm growth rateAortic valve typeSimilar natural historyAortic eventsConservative managementSmoking historyUnmatched cohortSpinal cord protection in open and endovascular approaches to thoracoabdominal aortic aneurysms
Amabile A, Lewis E, Costa V, Tadros RO, Han DK, Di Luozzo G. Spinal cord protection in open and endovascular approaches to thoracoabdominal aortic aneurysms. Vascular 2022, 31: 874-883. PMID: 35507464, DOI: 10.1177/17085381221094411.Peer-Reviewed Original ResearchConceptsSpinal cord injuryCord injuryAortic aneurysmSpinal cordDistal aortic perfusionSubclavian artery revascularizationSpinal cord protectionThoracoabdominal aortic aneurysmsCerebrospinal fluid drainageThoracic aortic aneurysmArtery revascularizationAortic repairEndovascular repairAortic perfusionAortic proceduresEndovascular approachSystemic hypothermiaPostoperative managementExtracorporeal circulationLocal edemaPersistent complicationsFluid drainageCurrent evidenceInjuryAdjunct
2021
Zone 0 Thoracic Endovascular Aortic Repair With Chimney Grafts: A Case Report and Review of the Literature
George J, Di Luozzo G, Faries P, Cornwall J, Tadros R, Marin M, McKinsey J, Han D. Zone 0 Thoracic Endovascular Aortic Repair With Chimney Grafts: A Case Report and Review of the Literature. Journal Of Vascular Surgery 2021, 74: e355. DOI: 10.1016/j.jvs.2021.07.041.Peer-Reviewed Original ResearchCommentary: A conceptual roadmap to spinal cord protection in thoracoabdominal aortic surgery
Rosati C, Di Luozzo G. Commentary: A conceptual roadmap to spinal cord protection in thoracoabdominal aortic surgery. JTCVS Techniques 2021, 8: 18-19. PMID: 34401796, PMCID: PMC8350601, DOI: 10.1016/j.xjtc.2021.02.013.Peer-Reviewed Original Research
2020
Discussion.
Di Luozzo G. Discussion. The Journal Of Thoracic And Cardiovascular Surgery 2020, 160: 1160-1161. PMID: 31669009, DOI: 10.1016/j.jtcvs.2019.09.086.Peer-Reviewed Original Research
2019
“Crab‐like” mitral valve endocarditis
Amabile A, Williams EE, Di Luozzo G, Balaram SK. “Crab‐like” mitral valve endocarditis. Journal Of Cardiac Surgery 2019, 35: 425-426. PMID: 31816121, DOI: 10.1111/jocs.14368.Peer-Reviewed Original ResearchSS24. Short-Term Outcomes of Open Thoracoabdominal Aortic Aneurysm Repairs: Analysis of the Society of Thoracic Surgeons Adult Cardiac Surgery Database
Mohebali J, Patel V, Di Luozzo G, Yerokun B, Xian Y, Thibault D, Shahian D, MacGillivray T. SS24. Short-Term Outcomes of Open Thoracoabdominal Aortic Aneurysm Repairs: Analysis of the Society of Thoracic Surgeons Adult Cardiac Surgery Database. Journal Of Vascular Surgery 2019, 69: e201. DOI: 10.1016/j.jvs.2019.04.288.Peer-Reviewed Original ResearchParaspinous muscle gene expression profiling following simulated staged endovascular repair of thoracoabdominal aortic aneurysm: exploring potential therapeutic pathways
Lewis ER, Geisbüsch S, Chang YJ, Costa V, Husain S, Soteropoulos P, Griepp RB, Di Luozzo G. Paraspinous muscle gene expression profiling following simulated staged endovascular repair of thoracoabdominal aortic aneurysm: exploring potential therapeutic pathways. European Journal Of Cardio-Thoracic Surgery 2019, 57: 30-38. PMID: 31006003, DOI: 10.1093/ejcts/ezz113.Peer-Reviewed Original ResearchConceptsAneurysm repairGene expression profilingCollateral networkThoracoabdominal aortic aneurysm repairSpinal collateral networkSpinal segmental arteriesSuch extensive proceduresThoracoabdominal aortic aneurysmsAortic aneurysm repairSpinal cord perfusionSpinal cord injuryPotential therapeutic pathwayExpression profilingArteriolar remodellingTAAA repairCord perfusionNeurological complicationsEndovascular repairNeuroprotective effectsEndovascular techniquesCord injuryAortic aneurysmCoil embolizationEndovascular coilingEndovascular intervention
2017
The Spinal Cord Collateral Network: Implications for Endovascular Aortic Repair
Geisbüsch S, Di Luozzo G, Griepp E, Griepp R. The Spinal Cord Collateral Network: Implications for Endovascular Aortic Repair. 2017, 105-112. DOI: 10.1007/978-3-319-15192-2_7.Peer-Reviewed Original ResearchTemporary aneurysm sac perfusionCollateral networkEndovascular aortic repairAortic repairDevastating complicationHypogastric arteryThoracoabdominal aortaIschemic damageEndovascular techniquesEndovascular coilingParaspinous musclesSpinal cordCollateral vasculatureArteryCordSubstantial numberVasculatureEndovascularComplicationsParaplegiaAortaPerfusion
2016
Planned Staged Repair of Thoracoabdominal Aortic Aneurysms to Minimize Spinal Cord Injury: A Proof of Concept
Di Luozzo G, Wilderman M, Pawale A, McCullough J, Griepp R. Planned Staged Repair of Thoracoabdominal Aortic Aneurysms to Minimize Spinal Cord Injury: A Proof of Concept. Aorta 2016, 3: 177-180. DOI: 10.12945/j.aorta.2016.15.003.Peer-Reviewed Original Research
2015
TCT-676 Prognostic Impact of Neutrophil to Lymphocyte Ratio in Patients Undergoing Transcatheter Aortic Valve Replacement
Dominguez Y, Mathur A, Angeli D, Cocke T, Vaidya P, Elmann E, Di Luozzo G, Ng A, Delaportas E, Hillary N, Parrillo J. TCT-676 Prognostic Impact of Neutrophil to Lymphocyte Ratio in Patients Undergoing Transcatheter Aortic Valve Replacement. Journal Of The American College Of Cardiology 2015, 66: b276-b277. DOI: 10.1016/j.jacc.2015.08.695.Peer-Reviewed Original ResearchGENDER DIFFERENCES IN LONG TERM SURVIVAL AFTER TRANS-CATHETER AORTIC VALVE REPLACEMENT IN PATIENTS WITH SEVERE AORTIC STENOSIS
Mathur A, Abdel-Razek A, Dominguez Y, Cocke T, Vaidya P, Andrews P, McCullough J, Elmann E, Di Luozzo G, Russo T, Parrillo J. GENDER DIFFERENCES IN LONG TERM SURVIVAL AFTER TRANS-CATHETER AORTIC VALVE REPLACEMENT IN PATIENTS WITH SEVERE AORTIC STENOSIS. Journal Of The American College Of Cardiology 2015, 65: a1855. DOI: 10.1016/s0735-1097(15)61855-1.Peer-Reviewed Original ResearchLONG-TERM SURVIVAL AND FOLLOW-UP IN PATIENTS WITH CONNECTIVE TISSUE DISORDERS UNDERGOING EXTENSIVE OPEN REPAIRS OF THORACOABDOMINAL AORTIC ANEURYSMS
Di Luozzo G, Lewis E, Geisbuesch S, Nyirenda T, Weiss A, Pawale A, Griepp R, Spielvogel D. LONG-TERM SURVIVAL AND FOLLOW-UP IN PATIENTS WITH CONNECTIVE TISSUE DISORDERS UNDERGOING EXTENSIVE OPEN REPAIRS OF THORACOABDOMINAL AORTIC ANEURYSMS. Journal Of The American College Of Cardiology 2015, 65: a2114. DOI: 10.1016/s0735-1097(15)62114-3.Peer-Reviewed Original Research
2013
Endovascular coil embolization of segmental arteries prevents paraplegia after subsequent thoracoabdominal aneurysm repair: An experimental model
Geisbüsch S, Stefanovic A, Koruth JS, Lin HM, Morgello S, Weisz DJ, Griepp RB, Di Luozzo G. Endovascular coil embolization of segmental arteries prevents paraplegia after subsequent thoracoabdominal aneurysm repair: An experimental model. Journal Of Thoracic And Cardiovascular Surgery 2013, 147: 220-227. PMID: 24220154, PMCID: PMC3918675, DOI: 10.1016/j.jtcvs.2013.09.022.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAortic Aneurysm, ThoracicBlood Vessel Prosthesis ImplantationEmbolization, TherapeuticEndovascular ProceduresHindlimbLumbosacral RegionModels, AnimalMuscle, SkeletalParaplegiaRecovery of FunctionRegional Blood FlowSpinal Cord IschemiaSwineThoracic ArteriesTime FactorsVideo RecordingConceptsSpinal cord injuryThoracoabdominal aneurysm repairHind limb functionSegmental arteriesTAAA repairAneurysm repairCord injuryGroup 2Tarlov scoreLimb functionCoil embolizationExperimental modelSpinal cordGroup 1Ischemic spinal cord injuryPostoperative spinal cord injuryHybrid TAAA repairJuvenile Yorkshire pigsLumbar segmental arteriesModified Tarlov scoreEndovascular coil embolizationLower thoracic/upper lumbar regionUpper lumbar regionPrevents paraplegiaHistopathologic injuryA prospective study of growth and rupture risk of small-to-moderate size ascending aortic aneurysms
Geisbüsch S, Stefanovic A, Schray D, Oyfe I, Lin HM, Di Luozzo G, Griepp RB. A prospective study of growth and rupture risk of small-to-moderate size ascending aortic aneurysms. Journal Of Thoracic And Cardiovascular Surgery 2013, 147: 68-74. PMID: 23953716, DOI: 10.1016/j.jtcvs.2013.06.030.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAnticoagulantsAortaAortic AneurysmAortic RuptureAortographyCase-Control StudiesChi-Square DistributionDisease ProgressionFemaleFibrinolytic AgentsHumansLeast-Squares AnalysisLinear ModelsMaleMiddle AgedPredictive Value of TestsPrognosisProspective StudiesRisk AssessmentRisk FactorsTime FactorsTomography, X-Ray ComputedVascular Surgical ProceduresConceptsTotal aortic volumeAscending Aortic AneurysmAortic aneurysmAortic volumeModerate size aneurysmsReference groupML/yearAntithrombotic medicationAortic pathologySurgical indicationsUnderwent operationAortic sizeProspective studyEmergency departmentAortic growthSurveillance groupLarge aneurysmsRisk factorsSinotubular junctionTomography scanTomography volume measurementsDissection riskPatientsCompelling indicationsAneurysmsHypothermia for aortic surgery
Griepp RB, Di Luozzo G. Hypothermia for aortic surgery. Journal Of Thoracic And Cardiovascular Surgery 2013, 145: s56-s58. PMID: 23410782, DOI: 10.1016/j.jtcvs.2012.11.072.Peer-Reviewed Original ResearchConceptsHypothermic circulatory arrestCirculatory arrestAcceptable neurologic outcomesAortic arch repairThoracoabdominal aortic aneurysmsAortic surgeryNeurologic outcomeArch repairSurgical patientsBrain metabolismOrgan protectionAortic aneurysmDeep hypothermiaClinical practicePig modelRoutine useHypothermiaArrestRepairPatientsSurgeryAneurysmsPerfusionPredicting the Risk for Acute Type B Aortic Dissection in Hypertensive Patients Using Anatomic Variables
Shirali AS, Bischoff MS, Lin HM, Oyfe I, Lookstein R, Griepp RB, Di Luozzo G. Predicting the Risk for Acute Type B Aortic Dissection in Hypertensive Patients Using Anatomic Variables. JACC Cardiovascular Imaging 2013, 6: 349-357. PMID: 23433926, DOI: 10.1016/j.jcmg.2012.07.018.Peer-Reviewed Original ResearchMeSH KeywordsAcute DiseaseAdultAgedAntihypertensive AgentsAorta, ThoracicAortic AneurysmAortic DissectionAortographyBlood PressureChi-Square DistributionFemaleHumansHypertensionLinear ModelsLogistic ModelsMaleMiddle AgedMultidetector Computed TomographyMultivariate AnalysisPredictive Value of TestsPrognosisReproducibility of ResultsRetrospective StudiesRisk AssessmentRisk FactorsROC CurveConceptsAcute type B aortic dissectionType B aortic dissectionHypertensive patientsB aortic dissectionAAD developmentAortic dissectionAortic archRisk factorsAortic tortuosityAggressive medical managementPre-emptive surgeryOnly risk factorProximal ascending aortaSignificant risk factorsAortic arch diameterStepwise logistic regressionNormotensive patientsAnatomic predictorsEntire aortaMedical managementArtery originAscending aortaTomography angiographyAortic rootAortic imaging
2012
Visceral and spinal cord protection during thoracoabdominal aortic aneurysm repair: Clinical and laboratory update
Di Luozzo G. Visceral and spinal cord protection during thoracoabdominal aortic aneurysm repair: Clinical and laboratory update. Journal Of Thoracic And Cardiovascular Surgery 2012, 145: s135-s138. PMID: 23260453, DOI: 10.1016/j.jtcvs.2012.11.053.Peer-Reviewed Original ResearchImaging of vascular remodeling after simulated thoracoabdominal aneurysm repair
Geisbüsch S, Schray D, Bischoff MS, Lin HM, Griepp RB, Di Luozzo G. Imaging of vascular remodeling after simulated thoracoabdominal aneurysm repair. Journal Of Thoracic And Cardiovascular Surgery 2012, 144: 1471-1478. PMID: 23010582, PMCID: PMC3496032, DOI: 10.1016/j.jtcvs.2012.08.062.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAortic Aneurysm, ThoracicArteriesBarium SulfateBehavior, AnimalCollateral CirculationContrast MediaDilatation, PathologicDisease Models, AnimalFemaleLatexLigationMammary ArteriesMultidetector Computed TomographyNeovascularization, PhysiologicParaplegiaReplica TechniquesSpinal CordSpinal Cord IschemiaSwineTime FactorsVascular Surgical ProceduresConceptsAnterior spinal arterySpinal cord blood supplySmall collateral vesselsAneurysm repairCollateral vesselsBlood supplyJuvenile Yorkshire pigsRisk of paraplegiaThoracoabdominal aneurysm repairThoracoabdominal aortic aneurysmsSpinal cord circulationEndovascular repairSpinal arteryArtery sacrificeIntercostal arteriesCord circulationInternal thoracicAortic aneurysmTomographic scanTomographic scanningVascular remodelingGroup 2Group 1Group 3Previous interventionsStaged approach for spinal cord protection in hybrid thoracoabdominal aortic aneurysm repair.
Bischoff MS, Brenner RM, Scheumann J, Zoli S, Di Luozzo G, Etz CD, Griepp RB. Staged approach for spinal cord protection in hybrid thoracoabdominal aortic aneurysm repair. Annals Of Cardiothoracic Surgery 2012, 1: 325-8. PMID: 23977515, PMCID: PMC3741777, DOI: 10.3978/j.issn.2225-319x.2012.06.03.Peer-Reviewed Original Research