2013
Endovascular coil embolization of segmental arteries prevents paraplegia after subsequent thoracoabdominal aneurysm repair: An experimental model
Geisbüsch S, Stefanovic A, Koruth JS, Lin HM, Morgello S, Weisz DJ, Griepp RB, Di Luozzo G. Endovascular coil embolization of segmental arteries prevents paraplegia after subsequent thoracoabdominal aneurysm repair: An experimental model. Journal Of Thoracic And Cardiovascular Surgery 2013, 147: 220-227. PMID: 24220154, PMCID: PMC3918675, DOI: 10.1016/j.jtcvs.2013.09.022.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAortic Aneurysm, ThoracicBlood Vessel Prosthesis ImplantationEmbolization, TherapeuticEndovascular ProceduresHindlimbLumbosacral RegionModels, AnimalMuscle, SkeletalParaplegiaRecovery of FunctionRegional Blood FlowSpinal Cord IschemiaSwineThoracic ArteriesTime FactorsVideo RecordingConceptsSpinal cord injuryThoracoabdominal aneurysm repairHind limb functionSegmental arteriesTAAA repairAneurysm repairCord injuryGroup 2Tarlov scoreLimb functionCoil embolizationExperimental modelSpinal cordGroup 1Ischemic spinal cord injuryPostoperative spinal cord injuryHybrid TAAA repairJuvenile Yorkshire pigsLumbar segmental arteriesModified Tarlov scoreEndovascular coil embolizationLower thoracic/upper lumbar regionUpper lumbar regionPrevents paraplegiaHistopathologic injury
2012
Imaging of vascular remodeling after simulated thoracoabdominal aneurysm repair
Geisbüsch S, Schray D, Bischoff MS, Lin HM, Griepp RB, Di Luozzo G. Imaging of vascular remodeling after simulated thoracoabdominal aneurysm repair. Journal Of Thoracic And Cardiovascular Surgery 2012, 144: 1471-1478. PMID: 23010582, PMCID: PMC3496032, DOI: 10.1016/j.jtcvs.2012.08.062.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAortic Aneurysm, ThoracicArteriesBarium SulfateBehavior, AnimalCollateral CirculationContrast MediaDilatation, PathologicDisease Models, AnimalFemaleLatexLigationMammary ArteriesMultidetector Computed TomographyNeovascularization, PhysiologicParaplegiaReplica TechniquesSpinal CordSpinal Cord IschemiaSwineTime FactorsVascular Surgical ProceduresConceptsAnterior spinal arterySpinal cord blood supplySmall collateral vesselsAneurysm repairCollateral vesselsBlood supplyJuvenile Yorkshire pigsRisk of paraplegiaThoracoabdominal aneurysm repairThoracoabdominal aortic aneurysmsSpinal cord circulationEndovascular repairSpinal arteryArtery sacrificeIntercostal arteriesCord circulationInternal thoracicAortic aneurysmTomographic scanTomographic scanningVascular remodelingGroup 2Group 1Group 3Previous interventions
2010
Measuring the collateral network pressure to minimize paraplegia risk in thoracoabdominal aneurysm resection
Etz CD, Zoli S, Bischoff MS, Bodian C, Di Luozzo G, Griepp RB. Measuring the collateral network pressure to minimize paraplegia risk in thoracoabdominal aneurysm resection. Journal Of Thoracic And Cardiovascular Surgery 2010, 140: s125-s130. PMID: 21092778, DOI: 10.1016/j.jtcvs.2010.07.040.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAortic Aneurysm, ThoracicBlood PressureBlood Pressure DeterminationCatheterization, PeripheralCentral Venous PressureCerebrospinal Fluid PressureCollateral CirculationDisease Models, AnimalHumansParaplegiaRisk AssessmentRisk FactorsSpinal CordSwineTime FactorsVascular Surgical ProceduresConceptsMean aortic pressureSpinal cord injurySegmental arteriesCord injuryAortic pressureSpinal cord perfusion pressureThoracoabdominal aortic aneurysm repairThoracoabdominal aneurysm resectionSpinal cord perfusionAortic aneurysm repairAneurysm resectionParaplegia riskDistal bypassCord perfusionHypogastric arteryAneurysm repairPerfusion pressureArterial ligationEpidural spaceCollateral networkParavertebral musclesPulsatile perfusionArteryOutflow pressureInjuryPredicting the Risk of Paraplegia After Thoracic and Thoracoabdominal Aneurysm Repair
Zoli S, Roder F, Etz CD, Brenner RM, Bodian CA, Lin HM, Di Luozzo G, Griepp RB. Predicting the Risk of Paraplegia After Thoracic and Thoracoabdominal Aneurysm Repair. The Annals Of Thoracic Surgery 2010, 90: 1237-1245. PMID: 20868820, DOI: 10.1016/j.athoracsur.2010.04.091.Peer-Reviewed Original ResearchConceptsSpinal cord injuryRisk of paraplegiaSegmental arteriesParaplegia riskEndovascular repairAneurysm repairCord injuryThoracoabdominal aortic aneurysm repairMotor-evoked potential monitoringPrevious aortic surgeryThoracoabdominal aneurysm repairIndependent risk factorThoracoabdominal aortic aneurysmsAortic aneurysm repairStandard surgical approachCerebrospinal fluid drainageCrawford classificationHospital mortalitySCI riskAortic surgeryEmergent operationSurgical approachAortic aneurysmRisk factorsAbdominal aortaExperimental Two-Stage Simulated Repair of Extensive Thoracoabdominal Aneurysms Reduces Paraplegia Risk
Zoli S, Etz CD, Roder F, Brenner RM, Bodian CA, Kleinman G, Di Luozzo G, Griepp RB. Experimental Two-Stage Simulated Repair of Extensive Thoracoabdominal Aneurysms Reduces Paraplegia Risk. The Annals Of Thoracic Surgery 2010, 90: 722-729. PMID: 20732484, DOI: 10.1016/j.athoracsur.2010.04.047.Peer-Reviewed Original ResearchConceptsSpinal cord perfusion pressureHind limb functionGroup 2Artery sacrificeLimb functionExtensive segmental artery sacrificeExtensive thoracoabdominal aneurysmsJuvenile Yorkshire pigsSevere ischemic damageMotor-evoked potentialsLumbar spinal cordSpinal cord functionModified Tarlov scoreSpinal cord injuryParaplegia riskTarlov scoreThoracoabdominal aneurysmsAneurysm repairCord functionDistal stumpIschemic damagePerfusion pressureCord injurySpinal cordLower thoracicStaged repair significantly reduces paraplegia rate after extensive thoracoabdominal aortic aneurysm repair
Etz CD, Zoli S, Mueller CS, Bodian CA, Di Luozzo G, Lazala R, Plestis KA, Griepp RB. Staged repair significantly reduces paraplegia rate after extensive thoracoabdominal aortic aneurysm repair. Journal Of Thoracic And Cardiovascular Surgery 2010, 139: 1464-1472. PMID: 20494193, DOI: 10.1016/j.jtcvs.2010.02.037.Peer-Reviewed Original ResearchConceptsExtensive thoracoabdominal aortic aneurysm repairExtensive segmental artery sacrificeThoracoabdominal aortic aneurysm repairThoracoabdominal aortic aneurysmsAortic aneurysm repairSpinal cord injuryArtery sacrificeAneurysm repairCord injuryAortic aneurysmCrawford type II thoracoabdominal aortic aneurysmType II thoracoabdominal aortic aneurysmIschemic spinal cord damageChronic obstructive pulmonary diseasePermanent spinal cord injuryExtensive thoracoabdominal aortic aneurysmsCrawford type ICrawford type IIIOverall hospital mortalityPrevious cerebrovascular accidentYear of procedureHypothermic circulatory arrestObstructive pulmonary diseaseOpen surgical repairMotor-evoked potentials