2013
A prospective study of growth and rupture risk of small-to-moderate size ascending aortic aneurysms
Geisbüsch S, Stefanovic A, Schray D, Oyfe I, Lin HM, Di Luozzo G, Griepp RB. A prospective study of growth and rupture risk of small-to-moderate size ascending aortic aneurysms. Journal Of Thoracic And Cardiovascular Surgery 2013, 147: 68-74. PMID: 23953716, DOI: 10.1016/j.jtcvs.2013.06.030.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAnticoagulantsAortaAortic AneurysmAortic RuptureAortographyCase-Control StudiesChi-Square DistributionDisease ProgressionFemaleFibrinolytic AgentsHumansLeast-Squares AnalysisLinear ModelsMaleMiddle AgedPredictive Value of TestsPrognosisProspective StudiesRisk AssessmentRisk FactorsTime FactorsTomography, X-Ray ComputedVascular Surgical ProceduresConceptsTotal aortic volumeAscending Aortic AneurysmAortic aneurysmAortic volumeModerate size aneurysmsReference groupML/yearAntithrombotic medicationAortic pathologySurgical indicationsUnderwent operationAortic sizeProspective studyEmergency departmentAortic growthSurveillance groupLarge aneurysmsRisk factorsSinotubular junctionTomography scanTomography volume measurementsDissection riskPatientsCompelling indicationsAneurysmsPredicting the Risk for Acute Type B Aortic Dissection in Hypertensive Patients Using Anatomic Variables
Shirali AS, Bischoff MS, Lin HM, Oyfe I, Lookstein R, Griepp RB, Di Luozzo G. Predicting the Risk for Acute Type B Aortic Dissection in Hypertensive Patients Using Anatomic Variables. JACC Cardiovascular Imaging 2013, 6: 349-357. PMID: 23433926, DOI: 10.1016/j.jcmg.2012.07.018.Peer-Reviewed Original ResearchMeSH KeywordsAcute DiseaseAdultAgedAntihypertensive AgentsAorta, ThoracicAortic AneurysmAortic DissectionAortographyBlood PressureChi-Square DistributionFemaleHumansHypertensionLinear ModelsLogistic ModelsMaleMiddle AgedMultidetector Computed TomographyMultivariate AnalysisPredictive Value of TestsPrognosisReproducibility of ResultsRetrospective StudiesRisk AssessmentRisk FactorsROC CurveConceptsAcute type B aortic dissectionType B aortic dissectionHypertensive patientsB aortic dissectionAAD developmentAortic dissectionAortic archRisk factorsAortic tortuosityAggressive medical managementPre-emptive surgeryOnly risk factorProximal ascending aortaSignificant risk factorsAortic arch diameterStepwise logistic regressionNormotensive patientsAnatomic predictorsEntire aortaMedical managementArtery originAscending aortaTomography angiographyAortic rootAortic imaging
2012
Open Repair of Descending and Thoracoabdominal Aortic Aneurysms and Dissections in Patients Aged Younger Than 60 Years: Superior to Endovascular Repair?
Di Luozzo G, Geisbüsch S, Lin HM, Bischoff MS, Schray D, Pawale A, Griepp RB. Open Repair of Descending and Thoracoabdominal Aortic Aneurysms and Dissections in Patients Aged Younger Than 60 Years: Superior to Endovascular Repair? The Annals Of Thoracic Surgery 2012, 95: 12-19. PMID: 22785215, DOI: 10.1016/j.athoracsur.2012.05.071.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAge FactorsAortic Aneurysm, ThoracicAortic DissectionBlood Vessel Prosthesis ImplantationCirculatory Arrest, Deep Hypothermia InducedFemaleFollow-Up StudiesHospital MortalityHumansMaleMiddle AgedNew YorkRetrospective StudiesStentsSurvival RateTime FactorsTreatment OutcomeYoung AdultConceptsThoracoabdominal aortic aneurysmsEndovascular repairOpen repairStent graftingAortic aneurysmDeep hypothermic circulatory arrestPrevious aortic operationHypothermic circulatory arrestOpen surgical repairNeurologic complication rateCerebrospinal fluid drainageModality of choiceChronic dissectionAcute dissectionAortic complicationsAortic operationsDiversity of patientsYounger patientsCirculatory arrestCommon indicationComplication rateNeurologic monitoringSurgical repairEarly mortalityLinearized rateFrequency of Reoperations in Patients With Marfan Syndrome
Geisbuesch S, Schray D, Bischoff MS, Lin HM, Di Luozzo G, Griepp RB. Frequency of Reoperations in Patients With Marfan Syndrome. The Annals Of Thoracic Surgery 2012, 93: 1496-1501. PMID: 22443865, DOI: 10.1016/j.athoracsur.2011.12.068.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAge DistributionAneurysm, RupturedAortic Aneurysm, ThoracicAortic DissectionChildCohort StudiesElective Surgical ProceduresEmergency TreatmentFemaleFollow-Up StudiesHumansIncidenceKaplan-Meier EstimateMaleMarfan SyndromeMiddle AgedRadiographyReoperationRetrospective StudiesSex DistributionStatistics, NonparametricSurvival AnalysisTime FactorsTreatment OutcomeVascular Surgical ProceduresYoung AdultConceptsInitial emergency surgeryMarfan patientsGroup IAortic operationsEmergency surgeryInitial operationAortic segmentsElective root replacementInfrarenal aortic replacementThoracic aortic operationsGroup II patientsAortic root repairFrequency of reoperationArch operationsReoperative mortalityTotal reoperationsAcute dissectionAortic replacementOperative mortalityRoot replacementSurgical patientsThoracoabdominal aortaAortic ruptureII patientsRoot dilatationSelective cerebral perfusion for thoracic aortic surgery: Association with neurocognitive outcome
Uysal S, Lin HM, Fischer GW, Di Luozzo G, Reich DL. Selective cerebral perfusion for thoracic aortic surgery: Association with neurocognitive outcome. Journal Of Thoracic And Cardiovascular Surgery 2012, 143: 1205-1212. PMID: 22306226, DOI: 10.1016/j.jtcvs.2012.01.012.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAorta, ThoracicCardiopulmonary BypassCerebrovascular CirculationChi-Square DistributionCirculatory Arrest, Deep Hypothermia InducedCognitionCognition DisordersFemaleHumansLinear ModelsLogistic ModelsMaleMiddle AgedNeuropsychological TestsNew York CityPerfusionProspective StudiesRisk AssessmentRisk FactorsTime FactorsTreatment OutcomeVascular Surgical ProceduresConceptsSelective cerebral perfusionHypothermic circulatory arrestSelective cerebral perfusion timeCerebral perfusion timeCardiopulmonary bypass timeThoracic aortic surgeryCerebral perfusionCardiopulmonary bypassCirculatory arrestAortic surgeryBypass timeSurgical patientsNeurocognitive outcomesPerfusion timeHypothermic circulatory arrest timeAortic arch surgeryBrain protection strategiesGroup 3 patientsOptimal brain protectionPostoperative neurocognitive testingGroup 1 patientsGroup 2 patientsThoracic aortic repairCirculatory arrest timeNeurocognitive test scores
2010
The Bentall procedure: Is it the gold standard? A series of 597 consecutive cases
Etz CD, Bischoff MS, Bodian C, Roder F, Brenner R, Griepp RB, Di Luozzo G. The Bentall procedure: Is it the gold standard? A series of 597 consecutive cases. Journal Of Thoracic And Cardiovascular Surgery 2010, 140: s64-s70. PMID: 21092800, DOI: 10.1016/j.jtcvs.2010.07.033.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAged, 80 and overAortic AneurysmAortic ValveBioprosthesisBlood Vessel Prosthesis ImplantationChi-Square DistributionFemaleHeart Valve ProsthesisHeart Valve Prosthesis ImplantationHospital MortalityHumansKaplan-Meier EstimateLogistic ModelsMaleMiddle AgedNew York CityOdds RatioProsthesis DesignReoperationRetrospective StudiesRisk AssessmentRisk FactorsTime FactorsTreatment OutcomeYoung AdultConceptsAortic root reconstructionLong-term survivalBiological valvesMechanical valvesBentall procedureRoot reconstructionOverall hospital mortalityIndependent risk factorCoronary artery diseaseShort-term outcomesLong-term outcomesChoice of valveHospital mortalityPatients 50Artery diseaseDegenerative etiologyLinearized rateAortic valveConsecutive casesRisk factorsEmergency operationGold standardReoperationPatientsSurvivalPredicting the Risk of Paraplegia After Thoracic and Thoracoabdominal Aneurysm Repair
Zoli S, Roder F, Etz CD, Brenner RM, Bodian CA, Lin HM, Di Luozzo G, Griepp RB. Predicting the Risk of Paraplegia After Thoracic and Thoracoabdominal Aneurysm Repair. The Annals Of Thoracic Surgery 2010, 90: 1237-1245. PMID: 20868820, DOI: 10.1016/j.athoracsur.2010.04.091.Peer-Reviewed Original ResearchConceptsSpinal cord injuryRisk of paraplegiaSegmental arteriesParaplegia riskEndovascular repairAneurysm repairCord injuryThoracoabdominal aortic aneurysm repairMotor-evoked potential monitoringPrevious aortic surgeryThoracoabdominal aneurysm repairIndependent risk factorThoracoabdominal aortic aneurysmsAortic aneurysm repairStandard surgical approachCerebrospinal fluid drainageCrawford classificationHospital mortalitySCI riskAortic surgeryEmergent operationSurgical approachAortic aneurysmRisk factorsAbdominal aortaExtracorporeal Peritoneovenous Shunt for the Management of Postaneurysmectomy Chylous Ascites in a Marfan Patient
Di Luozzo G, Scurlock C, Mechanick JI, Griepp RB. Extracorporeal Peritoneovenous Shunt for the Management of Postaneurysmectomy Chylous Ascites in a Marfan Patient. The Annals Of Thoracic Surgery 2010, 90: 281-284. PMID: 20609797, DOI: 10.1016/j.athoracsur.2009.12.020.Peer-Reviewed Original ResearchConceptsChylous ascitesPeritoneovenous shuntOpen abdominal aortic aneurysm repairAbdominal aortic aneurysm repairAortic aneurysm repairInitial therapeutic interventionAbdominal ascitesAneurysm repairUncommon complicationClinical statusRetroperitoneal surgeryMarfan patientsAscitesTherapeutic interventionsNutritional statusAggressive measuresPatientsShuntStatusComplicationsSurgeryEtiologyMortalityWomenLong-Term Survival After Open Repair of Chronic Distal Aortic Dissection
Zoli S, Etz CD, Roder F, Mueller CS, Brenner RM, Bodian CA, Di Luozzo G, Griepp RB. Long-Term Survival After Open Repair of Chronic Distal Aortic Dissection. The Annals Of Thoracic Surgery 2010, 89: 1458-1466. PMID: 20417761, DOI: 10.1016/j.athoracsur.2010.02.014.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAged, 80 and overAortic Aneurysm, AbdominalAortic Aneurysm, ThoracicAortic DissectionBlood Vessel Prosthesis ImplantationCause of DeathChronic DiseaseCohort StudiesDatabases, FactualDisease-Free SurvivalFemaleFollow-Up StudiesHospital MortalityHumansMaleMiddle AgedMultivariate AnalysisPostoperative ComplicationsProbabilityRisk AssessmentSurvival AnalysisTime FactorsTreatment OutcomeVascular Surgical ProceduresConceptsChronic distal aortic dissectionDistal aortic dissectionAortic dissectionOpen repairAdverse outcomesAcute type ADistal aortic reoperationEndovascular stent-graft techniquesSegmental artery pairsStent-graft techniqueThrombosed false lumenCoronary artery diseaseLong-term survivalAortic reoperationChronic dissectionHospital mortalityB dissectionChronic dialysisAortic expansionVisceral arteriesArtery diseaseSurgical repairFalse lumenInitial diagnosisAortic diameterMathematical model for describing cerebral oxygen desaturation in patients undergoing deep hypothermic circulatory arrest
Fischer GW, Benni PB, Lin H, Satyapriya A, Afonso A, Di Luozzo G, Griepp RB, Reich DL. Mathematical model for describing cerebral oxygen desaturation in patients undergoing deep hypothermic circulatory arrest. British Journal Of Anaesthesia 2010, 104: 59-66. PMID: 19933513, PMCID: PMC2791548, DOI: 10.1093/bja/aep335.Peer-Reviewed Original ResearchConceptsDeep hypothermic circulatory arrestHypothermic circulatory arrestCirculatory arrestCerebral desaturationArrest timeMin of DHCACerebral oxygen desaturationAortic arch diseaseArch diseaseAortic surgeryIschemic thresholdNeurological sequelaeOxygen desaturationCerebral oximetryCerebral ischaemiaSurgical treatmentPatient heightPatientsDesaturationArrestMixed modelsX logIschaemiaSequelaeSurgery
2009
Redo Lateral Thoracotomy for Reoperative Descending and Thoracoabdominal Aortic Repair: A Consecutive Series of 60 Patients
Etz CD, Zoli S, Kari FA, Mueller CS, Bodian CA, Di Luozzo G, Plestis KA, Griepp RB. Redo Lateral Thoracotomy for Reoperative Descending and Thoracoabdominal Aortic Repair: A Consecutive Series of 60 Patients. The Annals Of Thoracic Surgery 2009, 88: 758-767. PMID: 19699894, DOI: 10.1016/j.athoracsur.2009.04.140.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgedAged, 80 and overAortic Aneurysm, ThoracicAortic CoarctationAortic DiseasesAortic DissectionAtherosclerosisCardiopulmonary BypassCirculatory Arrest, Deep Hypothermia InducedEvoked Potentials, MotorEvoked Potentials, SomatosensoryFemaleHeart Bypass, LeftHospital MortalityHumansKaplan-Meier EstimateMaleMarfan SyndromeMiddle AgedNeurologic ExaminationPostoperative ComplicationsReoperationSurvival RateThoracotomyYoung AdultConceptsPartial left heart bypassSegmental artery pairsHypothermic circulatory arrestLeft heart bypassPartial cardiopulmonary bypassPermanent dialysisAtherosclerotic aneurysmsCirculatory arrestCardiopulmonary bypassHeart bypassAdverse outcomesExtensive adhesionsThoracoabdominal aortic aneurysm surgeryArtery pairsChronic obstructive pulmonary diseaseAortic aneurysm surgeryIntensive care unit recoveryObstructive pulmonary diseaseThoracoabdominal aortic repairCoronary artery diseaseAneurysm extentHospital mortalityRedo thoracotomyTAAA repairRespiratory complicationsDirect Spinal Cord Perfusion Pressure Monitoring in Extensive Distal Aortic Aneurysm Repair
Etz CD, Di Luozzo G, Zoli S, Lazala R, Plestis KA, Bodian CA, Griepp RB. Direct Spinal Cord Perfusion Pressure Monitoring in Extensive Distal Aortic Aneurysm Repair. The Annals Of Thoracic Surgery 2009, 87: 1764-1774. PMID: 19463592, DOI: 10.1016/j.athoracsur.2009.02.101.Peer-Reviewed Original ResearchConceptsSpinal cord perfusion pressureDeep hypothermic circulatory arrestThoracoabdominal aortic aneurysmsAortic aneurysm repairHypothermic circulatory arrestNonpulsatile cardiopulmonary bypassCardiopulmonary bypassPerfusion pressureSegmental arteriesEndovascular repairAneurysm repairCirculatory arrestAortic aneurysmThoracoabdominal aortic aneurysm repairNormal spinal cord functionPerfusion pressure monitoringThoracic segmental arteriesMean arterial pressureSpinal cord functionSpinal cord recoveryParaspinal collateral networkArterial pressureCord functionCollateral networkPressure monitoring
2007
Delayed Repair of Acute Type A Aortic Dissection in a Patient with Gastrointestinal Bleeding and Pulse Deficit
Di Luozzo G, Tannous HJ, Ellozy SH, Nowakowski S, Plestis KA, Adams DH, Griepp RB. Delayed Repair of Acute Type A Aortic Dissection in a Patient with Gastrointestinal Bleeding and Pulse Deficit. The Annals Of Thoracic Surgery 2007, 84: 2097-2099. PMID: 18036948, DOI: 10.1016/j.athoracsur.2007.06.077.Peer-Reviewed Original ResearchConceptsAortic dissectionAcute Type A Aortic DissectionType A Aortic DissectionA Aortic DissectionLife-threatening complicationsEnd-organ malperfusionAcute typeGastrointestinal bleedingPulse deficitLimb ischemiaSurgical emergencyPatientsConservative approachDissectionMalperfusionBleedingMesentericComplicationsIschemiaVascular Graft Replacement of the Ascending and Descending Aorta: Do Dacron Grafts Grow?
Etz CD, Homann T, Silovitz D, Bodian CA, Luehr M, Di Luozzo G, Plestis KA, Griepp RB. Vascular Graft Replacement of the Ascending and Descending Aorta: Do Dacron Grafts Grow? The Annals Of Thoracic Surgery 2007, 84: 1206-1213. PMID: 17888971, DOI: 10.1016/j.athoracsur.2007.05.034.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgedAged, 80 and overAortaAorta, ThoracicAortic DiseasesBlood Vessel ProsthesisBlood Vessel Prosthesis ImplantationChildCohort StudiesFemaleFollow-Up StudiesHumansMaleMiddle AgedPolyethylene TerephthalatesProbabilityProsthesis DesignProsthesis FailureReoperationRetrospective StudiesRisk AssessmentSurvival RateTreatment OutcomeConceptsDacron graftThoracic aortaGraft expansionPostoperative computed tomography scansAortic valve-sparing proceduresDevelopment of regurgitationDiseased aortic segmentMedian graft diameterRoutine postoperative surveillanceType III endoleakValve-sparing proceduresComputed tomography scanEntire thoracic aortaComputed tomography studyDacron vascular graftsVascular Dacron graftsVascular graft replacementAorta graftThoracoabdominal aneurysmsEndoluminal repairGraft replacementPostoperative surveillanceDescending AortaGraft diameterAortic segmentsAortic root reconstruction with a bioprosthetic valved conduit: A consecutive series of 275 procedures
Etz CD, Homann TM, Rane N, Bodian CA, Di Luozzo G, Plestis KA, Spielvogel D, Griepp RB. Aortic root reconstruction with a bioprosthetic valved conduit: A consecutive series of 275 procedures. Journal Of Thoracic And Cardiovascular Surgery 2007, 133: 1455-1463. PMID: 17532939, DOI: 10.1016/j.jtcvs.2007.01.058.Peer-Reviewed Original ResearchConceptsBioprosthetic valved conduitAortic root reconstructionValved conduitRoot reconstructionExtensive arch reconstructionOpen distal anastomosisPostoperative mortality rateAortic root replacementPatients 12 yearsRate of strokeHypothermic circulatory arrestLong-term outcomesLong-term survivalDegenerative aneurysmsHemiarch reconstructionHospital mortalityPermanent strokeAtherosclerotic aneurysmsRoot replacementArch reconstructionCirculatory arrestDistal anastomosisAdditional patientsDacron graftSignificant hemorrhagePulmonary Complications After Descending Thoracic and Thoracoabdominal Aortic Aneurysm Repair: Predictors, Prevention, and Treatment
Etz CD, Di Luozzo G, Bello R, Luehr M, Khan MZ, Bodian CA, Griepp RB, Plestis KA. Pulmonary Complications After Descending Thoracic and Thoracoabdominal Aortic Aneurysm Repair: Predictors, Prevention, and Treatment. The Annals Of Thoracic Surgery 2007, 83: s870-s876. PMID: 17257944, DOI: 10.1016/j.athoracsur.2006.10.099.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAged, 80 and overAortic Aneurysm, AbdominalAortic Aneurysm, ThoracicAortic RuptureBlood Urea NitrogenFemaleHemorrhageHospital MortalityHumansIntubation, IntratrachealLength of StayMaleMiddle AgedPlatelet TransfusionPrognosisRespiration DisordersRespiration, ArtificialTracheostomyVascular Surgical ProceduresConceptsPreoperative blood urea nitrogenThoracoabdominal aortic aneurysm repairDeep hypothermic circulatory arrestAortic aneurysm repairBlood urea nitrogenHospital stayPulmonary complicationsRespiratory complicationsIndependent predictorsAneurysm repairUrea nitrogenDistal aortic perfusionPreoperative renal insufficiencyProlonged postoperative ventilationMedian hospital stayPostoperative pulmonary complicationsAortic aneurysm surgeryProlonged hospital stayHypothermic circulatory arrestTransfusion of plateletsCurrent retrospective studyFemorofemoral bypassPostoperative ventilationHospital deathPostoperative bleeding
2004
Harmonic scalpel for pericardiectomy: novel approach to an old cardiac dilemma.
Di Luozzo G, Moussa F, Schor J, Traad E, Williams D, Carrillo R. Harmonic scalpel for pericardiectomy: novel approach to an old cardiac dilemma. The Heart Surgery Forum 2004, 7: e525-7. PMID: 15799939, DOI: 10.1532/hsf98.20041091.Peer-Reviewed Original ResearchConceptsUrgent cardiopulmonary bypassHarmonic scalpelCardiopulmonary bypassAdditional cardiac proceduresBloodless operative fieldCardiac traumaBlood transfusionMalignant arrhythmiasRetrospective reviewCardiac lacerationsExcessive bleedingCardiac proceduresDense adhesionsBlood productsPericardiectomyPatientsCalcific pericarditisOperative fieldBypassAdhesiolysisBleedingScalpelMortalityEpicardial surfacePericarditis