2012
Visceral and spinal cord protection during thoracoabdominal aortic aneurysm repair: Clinical and laboratory update
Di Luozzo G. Visceral and spinal cord protection during thoracoabdominal aortic aneurysm repair: Clinical and laboratory update. Journal Of Thoracic And Cardiovascular Surgery 2012, 145: s135-s138. PMID: 23260453, DOI: 10.1016/j.jtcvs.2012.11.053.Peer-Reviewed Original ResearchMeSH KeywordsAortic Aneurysm, ThoracicBlood Vessel Prosthesis ImplantationCirculatory Arrest, Deep Hypothermia InducedCollateral CirculationHemodynamicsHumansIschemiaPerfusionSpinal Cord IschemiaTreatment OutcomeVisceraOpen Repair of Descending and Thoracoabdominal Aortic Aneurysms and Dissections in Patients Aged Younger Than 60 Years: Superior to Endovascular Repair?
Di Luozzo G, Geisbüsch S, Lin HM, Bischoff MS, Schray D, Pawale A, Griepp RB. Open Repair of Descending and Thoracoabdominal Aortic Aneurysms and Dissections in Patients Aged Younger Than 60 Years: Superior to Endovascular Repair? The Annals Of Thoracic Surgery 2012, 95: 12-19. PMID: 22785215, DOI: 10.1016/j.athoracsur.2012.05.071.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAge FactorsAortic Aneurysm, ThoracicAortic DissectionBlood Vessel Prosthesis ImplantationCirculatory Arrest, Deep Hypothermia InducedFemaleFollow-Up StudiesHospital MortalityHumansMaleMiddle AgedNew YorkRetrospective StudiesStentsSurvival RateTime FactorsTreatment OutcomeYoung AdultConceptsThoracoabdominal aortic aneurysmsEndovascular repairOpen repairStent graftingAortic aneurysmDeep hypothermic circulatory arrestPrevious aortic operationHypothermic circulatory arrestOpen surgical repairNeurologic complication rateCerebrospinal fluid drainageModality of choiceChronic dissectionAcute dissectionAortic complicationsAortic operationsDiversity of patientsYounger patientsCirculatory arrestCommon indicationComplication rateNeurologic monitoringSurgical repairEarly mortalityLinearized rateCerebral Protection for Aortic Arch Surgery: Deep Hypothermia
Di Luozzo G, Griepp RB. Cerebral Protection for Aortic Arch Surgery: Deep Hypothermia. Seminars In Thoracic And Cardiovascular Surgery 2012, 24: 127-130. PMID: 22920529, DOI: 10.1053/j.semtcvs.2011.12.006.Peer-Reviewed Original ResearchMeSH KeywordsAorta, ThoracicAortic DiseasesBlood Vessel Prosthesis ImplantationCerebrovascular CirculationCerebrovascular DisordersCirculatory Arrest, Deep Hypothermia InducedHumansPerfusionTreatment OutcomeConceptsAortic arch surgeryArch surgeryDeep hypothermiaDeep hypothermic circulatory arrestBranched graft techniqueSelective cerebral perfusionTotal arch replacementHypothermic circulatory arrestAortic arch aneurysmArch replacementCerebral protectionArch aneurysmCerebral perfusionCirculatory arrestSurgical outcomesCardiac surgeonsGraft techniqueSurgeryHypothermiaAneurysmsPerfusionSurgeonsTechnical aspectsSelective cerebral perfusion for thoracic aortic surgery: Association with neurocognitive outcome
Uysal S, Lin HM, Fischer GW, Di Luozzo G, Reich DL. Selective cerebral perfusion for thoracic aortic surgery: Association with neurocognitive outcome. Journal Of Thoracic And Cardiovascular Surgery 2012, 143: 1205-1212. PMID: 22306226, DOI: 10.1016/j.jtcvs.2012.01.012.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAorta, ThoracicCardiopulmonary BypassCerebrovascular CirculationChi-Square DistributionCirculatory Arrest, Deep Hypothermia InducedCognitionCognition DisordersFemaleHumansLinear ModelsLogistic ModelsMaleMiddle AgedNeuropsychological TestsNew York CityPerfusionProspective StudiesRisk AssessmentRisk FactorsTime FactorsTreatment OutcomeVascular Surgical ProceduresConceptsSelective cerebral perfusionHypothermic circulatory arrestSelective cerebral perfusion timeCerebral perfusion timeCardiopulmonary bypass timeThoracic aortic surgeryCerebral perfusionCardiopulmonary bypassCirculatory arrestAortic surgeryBypass timeSurgical patientsNeurocognitive outcomesPerfusion timeHypothermic circulatory arrest timeAortic arch surgeryBrain protection strategiesGroup 3 patientsOptimal brain protectionPostoperative neurocognitive testingGroup 1 patientsGroup 2 patientsThoracic aortic repairCirculatory arrest timeNeurocognitive test scores
2011
A propensity score–matched comparison of deep versus mild hypothermia during thoracoabdominal aortic surgery
Weiss AJ, Lin HM, Bischoff MS, Scheumann J, Lazala R, Griepp RB, Di Luozzo G. A propensity score–matched comparison of deep versus mild hypothermia during thoracoabdominal aortic surgery. Journal Of Thoracic And Cardiovascular Surgery 2011, 143: 186-193. PMID: 21885069, DOI: 10.1016/j.jtcvs.2011.07.020.Peer-Reviewed Original ResearchMeSH KeywordsAortic Aneurysm, ThoracicCirculatory Arrest, Deep Hypothermia InducedFemaleHeart Arrest, InducedHumansMaleMiddle AgedPropensity ScoreRetrospective StudiesConceptsPermanent adverse outcomesThoracoabdominal aortic aneurysm repairDeep hypothermic circulatory arrestAortic aneurysm repairHypothermic circulatory arrestAdverse outcomesHypothermic circulatory arrest groupCirculatory arrest groupRenal failureLiver failureAneurysm repairCirculatory arrestArrest groupHypothermic circulatory arrest techniqueThoracoabdominal aortic aneurysm operationsPropensity score-matched analysisPropensity score-matched comparisonAortic aneurysm operationsPropensity-matched studySignificant decreased oddsThirty-day mortalityThoracoabdominal aortic surgeryAcute renal failureAdverse outcome ratesElephant trunk procedure
2010
Noninvasive cerebral oxygenation may predict outcome in patients undergoing aortic arch surgery
Fischer GW, Lin HM, Krol M, Galati MF, Di Luozzo G, Griepp RB, Reich DL. Noninvasive cerebral oxygenation may predict outcome in patients undergoing aortic arch surgery. Journal Of Thoracic And Cardiovascular Surgery 2010, 141: 815-821. PMID: 20579669, DOI: 10.1016/j.jtcvs.2010.05.017.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overAorta, ThoracicBlood Vessel Prosthesis ImplantationCardiopulmonary BypassCirculatory Arrest, Deep Hypothermia InducedCritical CareFemaleFrontal LobeHeart Arrest, InducedHospital CostsHumansLength of StayLogistic ModelsMaleMiddle AgedMonitoring, IntraoperativeNew York CityOximetryOxygenPostoperative ComplicationsPredictive Value of TestsRespiration, ArtificialRisk AssessmentRisk FactorsSeverity of Illness IndexTime FactorsTreatment OutcomeConceptsRegional oxygen saturationAortic arch surgeryArch surgeryOxygen saturationOrgan dysfunctionIntensive care unit lengthRegional oxygen saturation valuesTotal aortic arch replacementPostoperative organ dysfunctionAortic arch replacementExtended hospital staySevere adverse outcomesCerebral oxygenation valuesOxygen saturation valuesArch replacementHemiarch replacementExtubation timeHospital lengthHospital stayPostoperative complicationsCerebral oximetryMinor complicationsConsiderable morbidityMajor complicationsSurgical repairMathematical model for describing cerebral oxygen desaturation in patients undergoing deep hypothermic circulatory arrest
Fischer GW, Benni PB, Lin H, Satyapriya A, Afonso A, Di Luozzo G, Griepp RB, Reich DL. Mathematical model for describing cerebral oxygen desaturation in patients undergoing deep hypothermic circulatory arrest. British Journal Of Anaesthesia 2010, 104: 59-66. PMID: 19933513, PMCID: PMC2791548, DOI: 10.1093/bja/aep335.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAged, 80 and overAnesthesia, GeneralAorta, ThoracicBrain IschemiaCarbon DioxideCirculatory Arrest, Deep Hypothermia InducedFemaleHumansMaleMiddle AgedModels, BiologicalMonitoring, IntraoperativeOxygenOxygen ConsumptionPartial PressureConceptsDeep hypothermic circulatory arrestHypothermic circulatory arrestCirculatory arrestCerebral desaturationArrest timeMin of DHCACerebral oxygen desaturationAortic arch diseaseArch diseaseAortic surgeryIschemic thresholdNeurological sequelaeOxygen desaturationCerebral oximetryCerebral ischaemiaSurgical treatmentPatient heightPatientsDesaturationArrestMixed modelsX logIschaemiaSequelaeSurgery
2009
Redo Lateral Thoracotomy for Reoperative Descending and Thoracoabdominal Aortic Repair: A Consecutive Series of 60 Patients
Etz CD, Zoli S, Kari FA, Mueller CS, Bodian CA, Di Luozzo G, Plestis KA, Griepp RB. Redo Lateral Thoracotomy for Reoperative Descending and Thoracoabdominal Aortic Repair: A Consecutive Series of 60 Patients. The Annals Of Thoracic Surgery 2009, 88: 758-767. PMID: 19699894, DOI: 10.1016/j.athoracsur.2009.04.140.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgedAged, 80 and overAortic Aneurysm, ThoracicAortic CoarctationAortic DiseasesAortic DissectionAtherosclerosisCardiopulmonary BypassCirculatory Arrest, Deep Hypothermia InducedEvoked Potentials, MotorEvoked Potentials, SomatosensoryFemaleHeart Bypass, LeftHospital MortalityHumansKaplan-Meier EstimateMaleMarfan SyndromeMiddle AgedNeurologic ExaminationPostoperative ComplicationsReoperationSurvival RateThoracotomyYoung AdultConceptsPartial left heart bypassSegmental artery pairsHypothermic circulatory arrestLeft heart bypassPartial cardiopulmonary bypassPermanent dialysisAtherosclerotic aneurysmsCirculatory arrestCardiopulmonary bypassHeart bypassAdverse outcomesExtensive adhesionsThoracoabdominal aortic aneurysm surgeryArtery pairsChronic obstructive pulmonary diseaseAortic aneurysm surgeryIntensive care unit recoveryObstructive pulmonary diseaseThoracoabdominal aortic repairCoronary artery diseaseAneurysm extentHospital mortalityRedo thoracotomyTAAA repairRespiratory complications