2019
Paraspinous muscle gene expression profiling following simulated staged endovascular repair of thoracoabdominal aortic aneurysm: exploring potential therapeutic pathways
Lewis ER, Geisbüsch S, Chang YJ, Costa V, Husain S, Soteropoulos P, Griepp RB, Di Luozzo G. Paraspinous muscle gene expression profiling following simulated staged endovascular repair of thoracoabdominal aortic aneurysm: exploring potential therapeutic pathways. European Journal Of Cardio-Thoracic Surgery 2019, 57: 30-38. PMID: 31006003, DOI: 10.1093/ejcts/ezz113.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAortic Aneurysm, ThoracicBlood Vessel Prosthesis ImplantationEndovascular ProceduresGene Expression ProfilingMicroarray AnalysisMusclesSpinal Cord IschemiaSwineTreatment OutcomeVascular Endothelial Growth Factor AConceptsAneurysm repairGene expression profilingCollateral networkThoracoabdominal aortic aneurysm repairSpinal collateral networkSpinal segmental arteriesSuch extensive proceduresThoracoabdominal aortic aneurysmsAortic aneurysm repairSpinal cord perfusionSpinal cord injuryPotential therapeutic pathwayExpression profilingArteriolar remodellingTAAA repairCord perfusionNeurological complicationsEndovascular repairNeuroprotective effectsEndovascular techniquesCord injuryAortic aneurysmCoil embolizationEndovascular coilingEndovascular intervention
2013
Endovascular coil embolization of segmental arteries prevents paraplegia after subsequent thoracoabdominal aneurysm repair: An experimental model
Geisbüsch S, Stefanovic A, Koruth JS, Lin HM, Morgello S, Weisz DJ, Griepp RB, Di Luozzo G. Endovascular coil embolization of segmental arteries prevents paraplegia after subsequent thoracoabdominal aneurysm repair: An experimental model. Journal Of Thoracic And Cardiovascular Surgery 2013, 147: 220-227. PMID: 24220154, PMCID: PMC3918675, DOI: 10.1016/j.jtcvs.2013.09.022.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAortic Aneurysm, ThoracicBlood Vessel Prosthesis ImplantationEmbolization, TherapeuticEndovascular ProceduresHindlimbLumbosacral RegionModels, AnimalMuscle, SkeletalParaplegiaRecovery of FunctionRegional Blood FlowSpinal Cord IschemiaSwineThoracic ArteriesTime FactorsVideo RecordingConceptsSpinal cord injuryThoracoabdominal aneurysm repairHind limb functionSegmental arteriesTAAA repairAneurysm repairCord injuryGroup 2Tarlov scoreLimb functionCoil embolizationExperimental modelSpinal cordGroup 1Ischemic spinal cord injuryPostoperative spinal cord injuryHybrid TAAA repairJuvenile Yorkshire pigsLumbar segmental arteriesModified Tarlov scoreEndovascular coil embolizationLower thoracic/upper lumbar regionUpper lumbar regionPrevents paraplegiaHistopathologic injury
2012
Visceral and spinal cord protection during thoracoabdominal aortic aneurysm repair: Clinical and laboratory update
Di Luozzo G. Visceral and spinal cord protection during thoracoabdominal aortic aneurysm repair: Clinical and laboratory update. Journal Of Thoracic And Cardiovascular Surgery 2012, 145: s135-s138. PMID: 23260453, DOI: 10.1016/j.jtcvs.2012.11.053.Peer-Reviewed Original ResearchMeSH KeywordsAortic Aneurysm, ThoracicBlood Vessel Prosthesis ImplantationCirculatory Arrest, Deep Hypothermia InducedCollateral CirculationHemodynamicsHumansIschemiaPerfusionSpinal Cord IschemiaTreatment OutcomeVisceraOpen Repair of Descending and Thoracoabdominal Aortic Aneurysms and Dissections in Patients Aged Younger Than 60 Years: Superior to Endovascular Repair?
Di Luozzo G, Geisbüsch S, Lin HM, Bischoff MS, Schray D, Pawale A, Griepp RB. Open Repair of Descending and Thoracoabdominal Aortic Aneurysms and Dissections in Patients Aged Younger Than 60 Years: Superior to Endovascular Repair? The Annals Of Thoracic Surgery 2012, 95: 12-19. PMID: 22785215, DOI: 10.1016/j.athoracsur.2012.05.071.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAge FactorsAortic Aneurysm, ThoracicAortic DissectionBlood Vessel Prosthesis ImplantationCirculatory Arrest, Deep Hypothermia InducedFemaleFollow-Up StudiesHospital MortalityHumansMaleMiddle AgedNew YorkRetrospective StudiesStentsSurvival RateTime FactorsTreatment OutcomeYoung AdultConceptsThoracoabdominal aortic aneurysmsEndovascular repairOpen repairStent graftingAortic aneurysmDeep hypothermic circulatory arrestPrevious aortic operationHypothermic circulatory arrestOpen surgical repairNeurologic complication rateCerebrospinal fluid drainageModality of choiceChronic dissectionAcute dissectionAortic complicationsAortic operationsDiversity of patientsYounger patientsCirculatory arrestCommon indicationComplication rateNeurologic monitoringSurgical repairEarly mortalityLinearized rateCerebral Protection for Aortic Arch Surgery: Deep Hypothermia
Di Luozzo G, Griepp RB. Cerebral Protection for Aortic Arch Surgery: Deep Hypothermia. Seminars In Thoracic And Cardiovascular Surgery 2012, 24: 127-130. PMID: 22920529, DOI: 10.1053/j.semtcvs.2011.12.006.Peer-Reviewed Original ResearchMeSH KeywordsAorta, ThoracicAortic DiseasesBlood Vessel Prosthesis ImplantationCerebrovascular CirculationCerebrovascular DisordersCirculatory Arrest, Deep Hypothermia InducedHumansPerfusionTreatment OutcomeConceptsAortic arch surgeryArch surgeryDeep hypothermiaDeep hypothermic circulatory arrestBranched graft techniqueSelective cerebral perfusionTotal arch replacementHypothermic circulatory arrestAortic arch aneurysmArch replacementCerebral protectionArch aneurysmCerebral perfusionCirculatory arrestSurgical outcomesCardiac surgeonsGraft techniqueSurgeryHypothermiaAneurysmsPerfusionSurgeonsTechnical aspects
2011
Spinal Cord Preservation in Thoracoabdominal Aneurysm Repair
Bischoff MS, Di Luozzo G, Griepp EB, Griepp RB. Spinal Cord Preservation in Thoracoabdominal Aneurysm Repair. Perspectives In Vascular Surgery And Endovascular Therapy 2011, 23: 214-222. PMID: 21502113, DOI: 10.1177/1531003511400622.Peer-Reviewed Original ResearchConceptsSpinal cord injuryThoracoabdominal aneurysm repairAneurysm repairIncidence of paraplegiaSpinal cord preservationSpinal cord protectionEndovascular aortic repairOpen surgical repairSpinal cord vasculatureAortic repairEndovascular approachSurgical repairDreadful complicationCord injuryEndovascular proceduresCollateral networkInvasive natureRepairRecent technical advancementsParaparesisComplicationsParaplegiaInjuryIncidenceVasculature
2010
The Bentall procedure: Is it the gold standard? A series of 597 consecutive cases
Etz CD, Bischoff MS, Bodian C, Roder F, Brenner R, Griepp RB, Di Luozzo G. The Bentall procedure: Is it the gold standard? A series of 597 consecutive cases. Journal Of Thoracic And Cardiovascular Surgery 2010, 140: s64-s70. PMID: 21092800, DOI: 10.1016/j.jtcvs.2010.07.033.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAged, 80 and overAortic AneurysmAortic ValveBioprosthesisBlood Vessel Prosthesis ImplantationChi-Square DistributionFemaleHeart Valve ProsthesisHeart Valve Prosthesis ImplantationHospital MortalityHumansKaplan-Meier EstimateLogistic ModelsMaleMiddle AgedNew York CityOdds RatioProsthesis DesignReoperationRetrospective StudiesRisk AssessmentRisk FactorsTime FactorsTreatment OutcomeYoung AdultConceptsAortic root reconstructionLong-term survivalBiological valvesMechanical valvesBentall procedureRoot reconstructionOverall hospital mortalityIndependent risk factorCoronary artery diseaseShort-term outcomesLong-term outcomesChoice of valveHospital mortalityPatients 50Artery diseaseDegenerative etiologyLinearized rateAortic valveConsecutive casesRisk factorsEmergency operationGold standardReoperationPatientsSurvivalPredicting the Risk of Paraplegia After Thoracic and Thoracoabdominal Aneurysm Repair
Zoli S, Roder F, Etz CD, Brenner RM, Bodian CA, Lin HM, Di Luozzo G, Griepp RB. Predicting the Risk of Paraplegia After Thoracic and Thoracoabdominal Aneurysm Repair. The Annals Of Thoracic Surgery 2010, 90: 1237-1245. PMID: 20868820, DOI: 10.1016/j.athoracsur.2010.04.091.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgedAged, 80 and overAortic Aneurysm, ThoracicArteriesBlood Vessel Prosthesis ImplantationFemaleHumansMaleMiddle AgedParaplegiaReplantationRetrospective StudiesRisk FactorsSpinal Cord DiseasesYoung AdultConceptsSpinal cord injuryRisk of paraplegiaSegmental arteriesParaplegia riskEndovascular repairAneurysm repairCord injuryThoracoabdominal aortic aneurysm repairMotor-evoked potential monitoringPrevious aortic surgeryThoracoabdominal aneurysm repairIndependent risk factorThoracoabdominal aortic aneurysmsAortic aneurysm repairStandard surgical approachCerebrospinal fluid drainageCrawford classificationHospital mortalitySCI riskAortic surgeryEmergent operationSurgical approachAortic aneurysmRisk factorsAbdominal aortaExtracorporeal Peritoneovenous Shunt for the Management of Postaneurysmectomy Chylous Ascites in a Marfan Patient
Di Luozzo G, Scurlock C, Mechanick JI, Griepp RB. Extracorporeal Peritoneovenous Shunt for the Management of Postaneurysmectomy Chylous Ascites in a Marfan Patient. The Annals Of Thoracic Surgery 2010, 90: 281-284. PMID: 20609797, DOI: 10.1016/j.athoracsur.2009.12.020.Peer-Reviewed Original ResearchMeSH KeywordsAdultAortic AneurysmBlood Vessel Prosthesis ImplantationChylous AscitesFemaleHumansMarfan SyndromePeritoneovenous ShuntConceptsChylous ascitesPeritoneovenous shuntOpen abdominal aortic aneurysm repairAbdominal aortic aneurysm repairAortic aneurysm repairInitial therapeutic interventionAbdominal ascitesAneurysm repairUncommon complicationClinical statusRetroperitoneal surgeryMarfan patientsAscitesTherapeutic interventionsNutritional statusAggressive measuresPatientsShuntStatusComplicationsSurgeryEtiologyMortalityWomenNoninvasive cerebral oxygenation may predict outcome in patients undergoing aortic arch surgery
Fischer GW, Lin HM, Krol M, Galati MF, Di Luozzo G, Griepp RB, Reich DL. Noninvasive cerebral oxygenation may predict outcome in patients undergoing aortic arch surgery. Journal Of Thoracic And Cardiovascular Surgery 2010, 141: 815-821. PMID: 20579669, DOI: 10.1016/j.jtcvs.2010.05.017.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overAorta, ThoracicBlood Vessel Prosthesis ImplantationCardiopulmonary BypassCirculatory Arrest, Deep Hypothermia InducedCritical CareFemaleFrontal LobeHeart Arrest, InducedHospital CostsHumansLength of StayLogistic ModelsMaleMiddle AgedMonitoring, IntraoperativeNew York CityOximetryOxygenPostoperative ComplicationsPredictive Value of TestsRespiration, ArtificialRisk AssessmentRisk FactorsSeverity of Illness IndexTime FactorsTreatment OutcomeConceptsRegional oxygen saturationAortic arch surgeryArch surgeryOxygen saturationOrgan dysfunctionIntensive care unit lengthRegional oxygen saturation valuesTotal aortic arch replacementPostoperative organ dysfunctionAortic arch replacementExtended hospital staySevere adverse outcomesCerebral oxygenation valuesOxygen saturation valuesArch replacementHemiarch replacementExtubation timeHospital lengthHospital stayPostoperative complicationsCerebral oximetryMinor complicationsConsiderable morbidityMajor complicationsSurgical repairLong-Term Survival After Open Repair of Chronic Distal Aortic Dissection
Zoli S, Etz CD, Roder F, Mueller CS, Brenner RM, Bodian CA, Di Luozzo G, Griepp RB. Long-Term Survival After Open Repair of Chronic Distal Aortic Dissection. The Annals Of Thoracic Surgery 2010, 89: 1458-1466. PMID: 20417761, DOI: 10.1016/j.athoracsur.2010.02.014.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAged, 80 and overAortic Aneurysm, AbdominalAortic Aneurysm, ThoracicAortic DissectionBlood Vessel Prosthesis ImplantationCause of DeathChronic DiseaseCohort StudiesDatabases, FactualDisease-Free SurvivalFemaleFollow-Up StudiesHospital MortalityHumansMaleMiddle AgedMultivariate AnalysisPostoperative ComplicationsProbabilityRisk AssessmentSurvival AnalysisTime FactorsTreatment OutcomeVascular Surgical ProceduresConceptsChronic distal aortic dissectionDistal aortic dissectionAortic dissectionOpen repairAdverse outcomesAcute type ADistal aortic reoperationEndovascular stent-graft techniquesSegmental artery pairsStent-graft techniqueThrombosed false lumenCoronary artery diseaseLong-term survivalAortic reoperationChronic dissectionHospital mortalityB dissectionChronic dialysisAortic expansionVisceral arteriesArtery diseaseSurgical repairFalse lumenInitial diagnosisAortic diameter
2009
Aortic Arch Resection and Ligation of the Descending Thoracic Aorta to Manage a Ruptured Thoracoabdominal Aneurysm
Weiss A, Di Luozzo G, Etz CD, Griepp RB. Aortic Arch Resection and Ligation of the Descending Thoracic Aorta to Manage a Ruptured Thoracoabdominal Aneurysm. Vascular And Endovascular Surgery 2009, 43: 614-616. PMID: 19640920, DOI: 10.1177/1538574409335273.Peer-Reviewed Original ResearchMeSH KeywordsAgedAortic Aneurysm, ThoracicAortic RuptureAortographyBlood Vessel Prosthesis ImplantationFatal OutcomeHumansLigationMaleRecurrenceReoperationTomography, X-Ray ComputedTreatment OutcomeConceptsThoracoabdominal aortic aneurysmsAcute type B aortic dissectionType B aortic dissectionAortic arch resectionRuptured thoracoabdominal aneurysmHigh-risk patientsOpen surgical interventionOpen surgical repairB aortic dissectionThoracoabdominal aneurysmsAortic dissectionAortic ruptureEndovascular approachSurgical repairArch resectionSurgical interventionAortic aneurysmThoracic aortaPrimary operationPatientsAneurysmsLess conventional approachesRuptureReoperationResection
2008
Reoperative aortic root and transverse arch procedures: A comparison with contemporaneous primary operations
Etz CD, Plestis KA, Homann TM, Bodian CA, Di Luozzo G, Spielvogel D, Griepp RB. Reoperative aortic root and transverse arch procedures: A comparison with contemporaneous primary operations. Journal Of Thoracic And Cardiovascular Surgery 2008, 136: 860-867.e3. PMID: 18954623, DOI: 10.1016/j.jtcvs.2007.11.071.Peer-Reviewed Original ResearchMeSH KeywordsAgedAortic Aneurysm, ThoracicAortic ValveBlood Vessel Prosthesis ImplantationCase-Control StudiesCause of DeathFollow-Up StudiesHeart Valve DiseasesHeart Valve Prosthesis ImplantationHospital MortalityHumansIntraoperative ComplicationsKaplan-Meier EstimateMaleMiddle AgedMultivariate AnalysisPostoperative ComplicationsReoperationRetrospective StudiesTreatment OutcomeConceptsArch proceduresAorta proceduresArch operationsPrimary procedureOperative mortalityRisk factorsPoor long-term outlookSex-matched normal populationChronic obstructive pulmonary diseaseAortic arch operationsHigher hospital mortalityHigh operative mortalityProximal aortic surgeryLongevity of patientsObstructive pulmonary diseaseSeparate multivariable analysesLong-term outcomesSignificant risk factorsLong-term outlookLong-term survivalContemporaneous patientsAortic surgeryHospital mortalityEjection fractionMultivariable analysis
2007
Vascular Graft Replacement of the Ascending and Descending Aorta: Do Dacron Grafts Grow?
Etz CD, Homann T, Silovitz D, Bodian CA, Luehr M, Di Luozzo G, Plestis KA, Griepp RB. Vascular Graft Replacement of the Ascending and Descending Aorta: Do Dacron Grafts Grow? The Annals Of Thoracic Surgery 2007, 84: 1206-1213. PMID: 17888971, DOI: 10.1016/j.athoracsur.2007.05.034.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgedAged, 80 and overAortaAorta, ThoracicAortic DiseasesBlood Vessel ProsthesisBlood Vessel Prosthesis ImplantationChildCohort StudiesFemaleFollow-Up StudiesHumansMaleMiddle AgedPolyethylene TerephthalatesProbabilityProsthesis DesignProsthesis FailureReoperationRetrospective StudiesRisk AssessmentSurvival RateTreatment OutcomeConceptsDacron graftThoracic aortaGraft expansionPostoperative computed tomography scansAortic valve-sparing proceduresDevelopment of regurgitationDiseased aortic segmentMedian graft diameterRoutine postoperative surveillanceType III endoleakValve-sparing proceduresComputed tomography scanEntire thoracic aortaComputed tomography studyDacron vascular graftsVascular Dacron graftsVascular graft replacementAorta graftThoracoabdominal aneurysmsEndoluminal repairGraft replacementPostoperative surveillanceDescending AortaGraft diameterAortic segments
2005
Simultaneous Antegrade/Retrograde Normothermic Perfusion with Blood (Beating Heart) for Aortic Root Replacement in Acute Type‐A Dissection of the Aorta
Di Luozzo G, Panos AL, Lombardi P, Salerno TA. Simultaneous Antegrade/Retrograde Normothermic Perfusion with Blood (Beating Heart) for Aortic Root Replacement in Acute Type‐A Dissection of the Aorta. Journal Of Cardiac Surgery 2005, 20: 350-352. PMID: 15985136, DOI: 10.1111/j.1540-8191.2005.200463.x.Peer-Reviewed Original ResearchMeSH KeywordsAcute DiseaseAortic DiseasesAortic DissectionAortic ValveBlood Vessel Prosthesis ImplantationHumansMaleMiddle AgedMyocardial IschemiaMyocardial ReperfusionTemperatureTime Factors