2011
Staged Approach Prevents Spinal Cord Injury in Hybrid Surgical-Endovascular Thoracoabdominal Aortic Aneurysm Repair: An Experimental Model
Bischoff MS, Scheumann J, Brenner RM, Ladage D, Bodian CA, Kleinman G, Ellozy SH, Di Luozzo G, Etz CD, Griepp RB. Staged Approach Prevents Spinal Cord Injury in Hybrid Surgical-Endovascular Thoracoabdominal Aortic Aneurysm Repair: An Experimental Model. The Annals Of Thoracic Surgery 2011, 92: 138-146. PMID: 21718839, DOI: 10.1016/j.athoracsur.2011.03.098.Peer-Reviewed Original ResearchMeSH KeywordsAngiographyAngioplastyAnimalsAortic Aneurysm, ThoracicCombined Modality TherapyDisease Models, AnimalFemaleFollow-Up StudiesIntraoperative ComplicationsMonitoring, IntraoperativeRandom AllocationRisk AssessmentSpinal CordSpinal Cord InjuriesStentsSurvival RateSwineTreatment OutcomeVascular Surgical ProceduresConceptsGroup 1Group 2Thoracoabdominal aortic aneurysm repairJuvenile Yorkshire pigsSevere ischemic damageHind limb functionAortic aneurysm repairStent graft occlusionLumbar spinal cordModified Tarlov scoreSpinal cord injuryEndovascular coverageTarlov scoreGraft occlusionAneurysm repairArtery ligationIntercostal arteriesIschemic damageCord injuryLimb functionSudden occlusionSpinal cordLower thoracicHistopathologic analysisPorcine model
2010
Noninvasive cerebral oxygenation may predict outcome in patients undergoing aortic arch surgery
Fischer GW, Lin HM, Krol M, Galati MF, Di Luozzo G, Griepp RB, Reich DL. Noninvasive cerebral oxygenation may predict outcome in patients undergoing aortic arch surgery. Journal Of Thoracic And Cardiovascular Surgery 2010, 141: 815-821. PMID: 20579669, DOI: 10.1016/j.jtcvs.2010.05.017.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overAorta, ThoracicBlood Vessel Prosthesis ImplantationCardiopulmonary BypassCirculatory Arrest, Deep Hypothermia InducedCritical CareFemaleFrontal LobeHeart Arrest, InducedHospital CostsHumansLength of StayLogistic ModelsMaleMiddle AgedMonitoring, IntraoperativeNew York CityOximetryOxygenPostoperative ComplicationsPredictive Value of TestsRespiration, ArtificialRisk AssessmentRisk FactorsSeverity of Illness IndexTime FactorsTreatment OutcomeConceptsRegional oxygen saturationAortic arch surgeryArch surgeryOxygen saturationOrgan dysfunctionIntensive care unit lengthRegional oxygen saturation valuesTotal aortic arch replacementPostoperative organ dysfunctionAortic arch replacementExtended hospital staySevere adverse outcomesCerebral oxygenation valuesOxygen saturation valuesArch replacementHemiarch replacementExtubation timeHospital lengthHospital stayPostoperative complicationsCerebral oximetryMinor complicationsConsiderable morbidityMajor complicationsSurgical repairMathematical model for describing cerebral oxygen desaturation in patients undergoing deep hypothermic circulatory arrest
Fischer GW, Benni PB, Lin H, Satyapriya A, Afonso A, Di Luozzo G, Griepp RB, Reich DL. Mathematical model for describing cerebral oxygen desaturation in patients undergoing deep hypothermic circulatory arrest. British Journal Of Anaesthesia 2010, 104: 59-66. PMID: 19933513, PMCID: PMC2791548, DOI: 10.1093/bja/aep335.Peer-Reviewed Original ResearchConceptsDeep hypothermic circulatory arrestHypothermic circulatory arrestCirculatory arrestCerebral desaturationArrest timeMin of DHCACerebral oxygen desaturationAortic arch diseaseArch diseaseAortic surgeryIschemic thresholdNeurological sequelaeOxygen desaturationCerebral oximetryCerebral ischaemiaSurgical treatmentPatient heightPatientsDesaturationArrestMixed modelsX logIschaemiaSequelaeSurgery
2009
Direct Spinal Cord Perfusion Pressure Monitoring in Extensive Distal Aortic Aneurysm Repair
Etz CD, Di Luozzo G, Zoli S, Lazala R, Plestis KA, Bodian CA, Griepp RB. Direct Spinal Cord Perfusion Pressure Monitoring in Extensive Distal Aortic Aneurysm Repair. The Annals Of Thoracic Surgery 2009, 87: 1764-1774. PMID: 19463592, DOI: 10.1016/j.athoracsur.2009.02.101.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAged, 80 and overAortic AneurysmBlood PressureFemaleHumansMaleMiddle AgedMonitoring, IntraoperativeRegional Blood FlowSpinal CordConceptsSpinal cord perfusion pressureDeep hypothermic circulatory arrestThoracoabdominal aortic aneurysmsAortic aneurysm repairHypothermic circulatory arrestNonpulsatile cardiopulmonary bypassCardiopulmonary bypassPerfusion pressureSegmental arteriesEndovascular repairAneurysm repairCirculatory arrestAortic aneurysmThoracoabdominal aortic aneurysm repairNormal spinal cord functionPerfusion pressure monitoringThoracic segmental arteriesMean arterial pressureSpinal cord functionSpinal cord recoveryParaspinal collateral networkArterial pressureCord functionCollateral networkPressure monitoring