2013
A prospective study of growth and rupture risk of small-to-moderate size ascending aortic aneurysms
Geisbüsch S, Stefanovic A, Schray D, Oyfe I, Lin HM, Di Luozzo G, Griepp RB. A prospective study of growth and rupture risk of small-to-moderate size ascending aortic aneurysms. Journal Of Thoracic And Cardiovascular Surgery 2013, 147: 68-74. PMID: 23953716, DOI: 10.1016/j.jtcvs.2013.06.030.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAnticoagulantsAortaAortic AneurysmAortic RuptureAortographyCase-Control StudiesChi-Square DistributionDisease ProgressionFemaleFibrinolytic AgentsHumansLeast-Squares AnalysisLinear ModelsMaleMiddle AgedPredictive Value of TestsPrognosisProspective StudiesRisk AssessmentRisk FactorsTime FactorsTomography, X-Ray ComputedVascular Surgical ProceduresConceptsTotal aortic volumeAscending Aortic AneurysmAortic aneurysmAortic volumeModerate size aneurysmsReference groupML/yearAntithrombotic medicationAortic pathologySurgical indicationsUnderwent operationAortic sizeProspective studyEmergency departmentAortic growthSurveillance groupLarge aneurysmsRisk factorsSinotubular junctionTomography scanTomography volume measurementsDissection riskPatientsCompelling indicationsAneurysmsPredicting the Risk for Acute Type B Aortic Dissection in Hypertensive Patients Using Anatomic Variables
Shirali AS, Bischoff MS, Lin HM, Oyfe I, Lookstein R, Griepp RB, Di Luozzo G. Predicting the Risk for Acute Type B Aortic Dissection in Hypertensive Patients Using Anatomic Variables. JACC Cardiovascular Imaging 2013, 6: 349-357. PMID: 23433926, DOI: 10.1016/j.jcmg.2012.07.018.Peer-Reviewed Original ResearchMeSH KeywordsAcute DiseaseAdultAgedAntihypertensive AgentsAorta, ThoracicAortic AneurysmAortic DissectionAortographyBlood PressureChi-Square DistributionFemaleHumansHypertensionLinear ModelsLogistic ModelsMaleMiddle AgedMultidetector Computed TomographyMultivariate AnalysisPredictive Value of TestsPrognosisReproducibility of ResultsRetrospective StudiesRisk AssessmentRisk FactorsROC CurveConceptsAcute type B aortic dissectionType B aortic dissectionHypertensive patientsB aortic dissectionAAD developmentAortic dissectionAortic archRisk factorsAortic tortuosityAggressive medical managementPre-emptive surgeryOnly risk factorProximal ascending aortaSignificant risk factorsAortic arch diameterStepwise logistic regressionNormotensive patientsAnatomic predictorsEntire aortaMedical managementArtery originAscending aortaTomography angiographyAortic rootAortic imaging
2012
Quality of life and survival of septuagenarians and octogenarians after repair of descending and thoracoabdominal aortic aneurysms
Di Luozzo G, Shirali AS, Varghese R, Lin HM, Weiss AJ, Bischoff MS, Griepp RB. Quality of life and survival of septuagenarians and octogenarians after repair of descending and thoracoabdominal aortic aneurysms. Journal Of Thoracic And Cardiovascular Surgery 2012, 145: 378-384. PMID: 22365063, DOI: 10.1016/j.jtcvs.2012.01.068.Peer-Reviewed Original ResearchMeSH KeywordsAge FactorsAgedAged, 80 and overAortic Aneurysm, ThoracicFemaleHospital MortalityHumansKaplan-Meier EstimateLogistic ModelsMaleOdds RatioProportional Hazards ModelsQuality of LifeRespiratory Distress SyndromeRetrospective StudiesRisk AssessmentRisk FactorsSex FactorsSurveys and QuestionnairesTime FactorsTreatment OutcomeVascular Surgical ProceduresConceptsQuality of lifeBody mass indexGender-matched populationLong-term survivalHospital mortalityMass indexThoracoabdominal aortic aneurysm repairAcute respiratory distress syndromeHigher body mass indexComplex aortic operationsOne-year survivalThoracoabdominal aortic aneurysmsAortic aneurysm repairItem Health SurveyRespiratory distress syndromeLower vitality scoresTAAA repairAortic operationsElderly patientsAneurysm repairDistress syndromePostoperative qualityRetrospective reviewThoracic aneurysmLife scoresSelective cerebral perfusion for thoracic aortic surgery: Association with neurocognitive outcome
Uysal S, Lin HM, Fischer GW, Di Luozzo G, Reich DL. Selective cerebral perfusion for thoracic aortic surgery: Association with neurocognitive outcome. Journal Of Thoracic And Cardiovascular Surgery 2012, 143: 1205-1212. PMID: 22306226, DOI: 10.1016/j.jtcvs.2012.01.012.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAorta, ThoracicCardiopulmonary BypassCerebrovascular CirculationChi-Square DistributionCirculatory Arrest, Deep Hypothermia InducedCognitionCognition DisordersFemaleHumansLinear ModelsLogistic ModelsMaleMiddle AgedNeuropsychological TestsNew York CityPerfusionProspective StudiesRisk AssessmentRisk FactorsTime FactorsTreatment OutcomeVascular Surgical ProceduresConceptsSelective cerebral perfusionHypothermic circulatory arrestSelective cerebral perfusion timeCerebral perfusion timeCardiopulmonary bypass timeThoracic aortic surgeryCerebral perfusionCardiopulmonary bypassCirculatory arrestAortic surgeryBypass timeSurgical patientsNeurocognitive outcomesPerfusion timeHypothermic circulatory arrest timeAortic arch surgeryBrain protection strategiesGroup 3 patientsOptimal brain protectionPostoperative neurocognitive testingGroup 1 patientsGroup 2 patientsThoracic aortic repairCirculatory arrest timeNeurocognitive test scores
2010
Measuring the collateral network pressure to minimize paraplegia risk in thoracoabdominal aneurysm resection
Etz CD, Zoli S, Bischoff MS, Bodian C, Di Luozzo G, Griepp RB. Measuring the collateral network pressure to minimize paraplegia risk in thoracoabdominal aneurysm resection. Journal Of Thoracic And Cardiovascular Surgery 2010, 140: s125-s130. PMID: 21092778, DOI: 10.1016/j.jtcvs.2010.07.040.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAortic Aneurysm, ThoracicBlood PressureBlood Pressure DeterminationCatheterization, PeripheralCentral Venous PressureCerebrospinal Fluid PressureCollateral CirculationDisease Models, AnimalHumansParaplegiaRisk AssessmentRisk FactorsSpinal CordSwineTime FactorsVascular Surgical ProceduresConceptsMean aortic pressureSpinal cord injurySegmental arteriesCord injuryAortic pressureSpinal cord perfusion pressureThoracoabdominal aortic aneurysm repairThoracoabdominal aneurysm resectionSpinal cord perfusionAortic aneurysm repairAneurysm resectionParaplegia riskDistal bypassCord perfusionHypogastric arteryAneurysm repairPerfusion pressureArterial ligationEpidural spaceCollateral networkParavertebral musclesPulsatile perfusionArteryOutflow pressureInjuryThe Bentall procedure: Is it the gold standard? A series of 597 consecutive cases
Etz CD, Bischoff MS, Bodian C, Roder F, Brenner R, Griepp RB, Di Luozzo G. The Bentall procedure: Is it the gold standard? A series of 597 consecutive cases. Journal Of Thoracic And Cardiovascular Surgery 2010, 140: s64-s70. PMID: 21092800, DOI: 10.1016/j.jtcvs.2010.07.033.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAged, 80 and overAortic AneurysmAortic ValveBioprosthesisBlood Vessel Prosthesis ImplantationChi-Square DistributionFemaleHeart Valve ProsthesisHeart Valve Prosthesis ImplantationHospital MortalityHumansKaplan-Meier EstimateLogistic ModelsMaleMiddle AgedNew York CityOdds RatioProsthesis DesignReoperationRetrospective StudiesRisk AssessmentRisk FactorsTime FactorsTreatment OutcomeYoung AdultConceptsAortic root reconstructionLong-term survivalBiological valvesMechanical valvesBentall procedureRoot reconstructionOverall hospital mortalityIndependent risk factorCoronary artery diseaseShort-term outcomesLong-term outcomesChoice of valveHospital mortalityPatients 50Artery diseaseDegenerative etiologyLinearized rateAortic valveConsecutive casesRisk factorsEmergency operationGold standardReoperationPatientsSurvivalPredicting the Risk of Paraplegia After Thoracic and Thoracoabdominal Aneurysm Repair
Zoli S, Roder F, Etz CD, Brenner RM, Bodian CA, Lin HM, Di Luozzo G, Griepp RB. Predicting the Risk of Paraplegia After Thoracic and Thoracoabdominal Aneurysm Repair. The Annals Of Thoracic Surgery 2010, 90: 1237-1245. PMID: 20868820, DOI: 10.1016/j.athoracsur.2010.04.091.Peer-Reviewed Original ResearchConceptsSpinal cord injuryRisk of paraplegiaSegmental arteriesParaplegia riskEndovascular repairAneurysm repairCord injuryThoracoabdominal aortic aneurysm repairMotor-evoked potential monitoringPrevious aortic surgeryThoracoabdominal aneurysm repairIndependent risk factorThoracoabdominal aortic aneurysmsAortic aneurysm repairStandard surgical approachCerebrospinal fluid drainageCrawford classificationHospital mortalitySCI riskAortic surgeryEmergent operationSurgical approachAortic aneurysmRisk factorsAbdominal aortaExperimental Two-Stage Simulated Repair of Extensive Thoracoabdominal Aneurysms Reduces Paraplegia Risk
Zoli S, Etz CD, Roder F, Brenner RM, Bodian CA, Kleinman G, Di Luozzo G, Griepp RB. Experimental Two-Stage Simulated Repair of Extensive Thoracoabdominal Aneurysms Reduces Paraplegia Risk. The Annals Of Thoracic Surgery 2010, 90: 722-729. PMID: 20732484, DOI: 10.1016/j.athoracsur.2010.04.047.Peer-Reviewed Original ResearchConceptsSpinal cord perfusion pressureHind limb functionGroup 2Artery sacrificeLimb functionExtensive segmental artery sacrificeExtensive thoracoabdominal aneurysmsJuvenile Yorkshire pigsSevere ischemic damageMotor-evoked potentialsLumbar spinal cordSpinal cord functionModified Tarlov scoreSpinal cord injuryParaplegia riskTarlov scoreThoracoabdominal aneurysmsAneurysm repairCord functionDistal stumpIschemic damagePerfusion pressureCord injurySpinal cordLower thoracicNoninvasive cerebral oxygenation may predict outcome in patients undergoing aortic arch surgery
Fischer GW, Lin HM, Krol M, Galati MF, Di Luozzo G, Griepp RB, Reich DL. Noninvasive cerebral oxygenation may predict outcome in patients undergoing aortic arch surgery. Journal Of Thoracic And Cardiovascular Surgery 2010, 141: 815-821. PMID: 20579669, DOI: 10.1016/j.jtcvs.2010.05.017.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overAorta, ThoracicBlood Vessel Prosthesis ImplantationCardiopulmonary BypassCirculatory Arrest, Deep Hypothermia InducedCritical CareFemaleFrontal LobeHeart Arrest, InducedHospital CostsHumansLength of StayLogistic ModelsMaleMiddle AgedMonitoring, IntraoperativeNew York CityOximetryOxygenPostoperative ComplicationsPredictive Value of TestsRespiration, ArtificialRisk AssessmentRisk FactorsSeverity of Illness IndexTime FactorsTreatment OutcomeConceptsRegional oxygen saturationAortic arch surgeryArch surgeryOxygen saturationOrgan dysfunctionIntensive care unit lengthRegional oxygen saturation valuesTotal aortic arch replacementPostoperative organ dysfunctionAortic arch replacementExtended hospital staySevere adverse outcomesCerebral oxygenation valuesOxygen saturation valuesArch replacementHemiarch replacementExtubation timeHospital lengthHospital stayPostoperative complicationsCerebral oximetryMinor complicationsConsiderable morbidityMajor complicationsSurgical repair
2007
Aortic root reconstruction with a bioprosthetic valved conduit: A consecutive series of 275 procedures
Etz CD, Homann TM, Rane N, Bodian CA, Di Luozzo G, Plestis KA, Spielvogel D, Griepp RB. Aortic root reconstruction with a bioprosthetic valved conduit: A consecutive series of 275 procedures. Journal Of Thoracic And Cardiovascular Surgery 2007, 133: 1455-1463. PMID: 17532939, DOI: 10.1016/j.jtcvs.2007.01.058.Peer-Reviewed Original ResearchConceptsBioprosthetic valved conduitAortic root reconstructionValved conduitRoot reconstructionExtensive arch reconstructionOpen distal anastomosisPostoperative mortality rateAortic root replacementPatients 12 yearsRate of strokeHypothermic circulatory arrestLong-term outcomesLong-term survivalDegenerative aneurysmsHemiarch reconstructionHospital mortalityPermanent strokeAtherosclerotic aneurysmsRoot replacementArch reconstructionCirculatory arrestDistal anastomosisAdditional patientsDacron graftSignificant hemorrhage