2022
Spinal cord protection in open and endovascular approaches to thoracoabdominal aortic aneurysms
Amabile A, Lewis E, Costa V, Tadros RO, Han DK, Di Luozzo G. Spinal cord protection in open and endovascular approaches to thoracoabdominal aortic aneurysms. Vascular 2022, 31: 874-883. PMID: 35507464, DOI: 10.1177/17085381221094411.Peer-Reviewed Original ResearchConceptsSpinal cord injuryCord injuryAortic aneurysmSpinal cordDistal aortic perfusionSubclavian artery revascularizationSpinal cord protectionThoracoabdominal aortic aneurysmsCerebrospinal fluid drainageThoracic aortic aneurysmArtery revascularizationAortic repairEndovascular repairAortic perfusionAortic proceduresEndovascular approachSystemic hypothermiaPostoperative managementExtracorporeal circulationLocal edemaPersistent complicationsFluid drainageCurrent evidenceInjuryAdjunct
2019
Paraspinous muscle gene expression profiling following simulated staged endovascular repair of thoracoabdominal aortic aneurysm: exploring potential therapeutic pathways
Lewis ER, Geisbüsch S, Chang YJ, Costa V, Husain S, Soteropoulos P, Griepp RB, Di Luozzo G. Paraspinous muscle gene expression profiling following simulated staged endovascular repair of thoracoabdominal aortic aneurysm: exploring potential therapeutic pathways. European Journal Of Cardio-Thoracic Surgery 2019, 57: 30-38. PMID: 31006003, DOI: 10.1093/ejcts/ezz113.Peer-Reviewed Original ResearchConceptsAneurysm repairGene expression profilingCollateral networkThoracoabdominal aortic aneurysm repairSpinal collateral networkSpinal segmental arteriesSuch extensive proceduresThoracoabdominal aortic aneurysmsAortic aneurysm repairSpinal cord perfusionSpinal cord injuryPotential therapeutic pathwayExpression profilingArteriolar remodellingTAAA repairCord perfusionNeurological complicationsEndovascular repairNeuroprotective effectsEndovascular techniquesCord injuryAortic aneurysmCoil embolizationEndovascular coilingEndovascular intervention
2012
Imaging of vascular remodeling after simulated thoracoabdominal aneurysm repair
Geisbüsch S, Schray D, Bischoff MS, Lin HM, Griepp RB, Di Luozzo G. Imaging of vascular remodeling after simulated thoracoabdominal aneurysm repair. Journal Of Thoracic And Cardiovascular Surgery 2012, 144: 1471-1478. PMID: 23010582, PMCID: PMC3496032, DOI: 10.1016/j.jtcvs.2012.08.062.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAortic Aneurysm, ThoracicArteriesBarium SulfateBehavior, AnimalCollateral CirculationContrast MediaDilatation, PathologicDisease Models, AnimalFemaleLatexLigationMammary ArteriesMultidetector Computed TomographyNeovascularization, PhysiologicParaplegiaReplica TechniquesSpinal CordSpinal Cord IschemiaSwineTime FactorsVascular Surgical ProceduresConceptsAnterior spinal arterySpinal cord blood supplySmall collateral vesselsAneurysm repairCollateral vesselsBlood supplyJuvenile Yorkshire pigsRisk of paraplegiaThoracoabdominal aneurysm repairThoracoabdominal aortic aneurysmsSpinal cord circulationEndovascular repairSpinal arteryArtery sacrificeIntercostal arteriesCord circulationInternal thoracicAortic aneurysmTomographic scanTomographic scanningVascular remodelingGroup 2Group 1Group 3Previous interventionsOpen Repair of Descending and Thoracoabdominal Aortic Aneurysms and Dissections in Patients Aged Younger Than 60 Years: Superior to Endovascular Repair?
Di Luozzo G, Geisbüsch S, Lin HM, Bischoff MS, Schray D, Pawale A, Griepp RB. Open Repair of Descending and Thoracoabdominal Aortic Aneurysms and Dissections in Patients Aged Younger Than 60 Years: Superior to Endovascular Repair? The Annals Of Thoracic Surgery 2012, 95: 12-19. PMID: 22785215, DOI: 10.1016/j.athoracsur.2012.05.071.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAge FactorsAortic Aneurysm, ThoracicAortic DissectionBlood Vessel Prosthesis ImplantationCirculatory Arrest, Deep Hypothermia InducedFemaleFollow-Up StudiesHospital MortalityHumansMaleMiddle AgedNew YorkRetrospective StudiesStentsSurvival RateTime FactorsTreatment OutcomeYoung AdultConceptsThoracoabdominal aortic aneurysmsEndovascular repairOpen repairStent graftingAortic aneurysmDeep hypothermic circulatory arrestPrevious aortic operationHypothermic circulatory arrestOpen surgical repairNeurologic complication rateCerebrospinal fluid drainageModality of choiceChronic dissectionAcute dissectionAortic complicationsAortic operationsDiversity of patientsYounger patientsCirculatory arrestCommon indicationComplication rateNeurologic monitoringSurgical repairEarly mortalityLinearized rate
2010
Predicting the Risk of Paraplegia After Thoracic and Thoracoabdominal Aneurysm Repair
Zoli S, Roder F, Etz CD, Brenner RM, Bodian CA, Lin HM, Di Luozzo G, Griepp RB. Predicting the Risk of Paraplegia After Thoracic and Thoracoabdominal Aneurysm Repair. The Annals Of Thoracic Surgery 2010, 90: 1237-1245. PMID: 20868820, DOI: 10.1016/j.athoracsur.2010.04.091.Peer-Reviewed Original ResearchConceptsSpinal cord injuryRisk of paraplegiaSegmental arteriesParaplegia riskEndovascular repairAneurysm repairCord injuryThoracoabdominal aortic aneurysm repairMotor-evoked potential monitoringPrevious aortic surgeryThoracoabdominal aneurysm repairIndependent risk factorThoracoabdominal aortic aneurysmsAortic aneurysm repairStandard surgical approachCerebrospinal fluid drainageCrawford classificationHospital mortalitySCI riskAortic surgeryEmergent operationSurgical approachAortic aneurysmRisk factorsAbdominal aorta
2009
Direct Spinal Cord Perfusion Pressure Monitoring in Extensive Distal Aortic Aneurysm Repair
Etz CD, Di Luozzo G, Zoli S, Lazala R, Plestis KA, Bodian CA, Griepp RB. Direct Spinal Cord Perfusion Pressure Monitoring in Extensive Distal Aortic Aneurysm Repair. The Annals Of Thoracic Surgery 2009, 87: 1764-1774. PMID: 19463592, DOI: 10.1016/j.athoracsur.2009.02.101.Peer-Reviewed Original ResearchConceptsSpinal cord perfusion pressureDeep hypothermic circulatory arrestThoracoabdominal aortic aneurysmsAortic aneurysm repairHypothermic circulatory arrestNonpulsatile cardiopulmonary bypassCardiopulmonary bypassPerfusion pressureSegmental arteriesEndovascular repairAneurysm repairCirculatory arrestAortic aneurysmThoracoabdominal aortic aneurysm repairNormal spinal cord functionPerfusion pressure monitoringThoracic segmental arteriesMean arterial pressureSpinal cord functionSpinal cord recoveryParaspinal collateral networkArterial pressureCord functionCollateral networkPressure monitoring