2011
Non-invasive imaging in acute chest pain syndromes
Sechtem U, Achenbach S, Friedrich M, Wackers F, Zamorano J. Non-invasive imaging in acute chest pain syndromes. European Heart Journal - Cardiovascular Imaging 2011, 13: 69-78. PMID: 22094238, DOI: 10.1093/ejechocard/jer250.Peer-Reviewed Original Research
2005
A Randomized, Double-Blind, Placebo-Controlled Study of the Safety and Efficacy of Intravenous MCC-135 as an Adjunct to Primary Percutaneous Coronary Intervention in Patients with Acute Myocardial Infarction: Rationale and Design of the Evaluation of MCC-135 for Left Ventricular Salvage in Acute MI (EVOLVE) Study
Jang I, Pettigrew V, Picard M, Kowey P, Demmel V, Zile M, Tatsuno J, Wackers F, Hibberd M. A Randomized, Double-Blind, Placebo-Controlled Study of the Safety and Efficacy of Intravenous MCC-135 as an Adjunct to Primary Percutaneous Coronary Intervention in Patients with Acute Myocardial Infarction: Rationale and Design of the Evaluation of MCC-135 for Left Ventricular Salvage in Acute MI (EVOLVE) Study. Journal Of Thrombosis And Thrombolysis 2005, 20: 147-153. PMID: 16261287, DOI: 10.1007/s11239-005-3267-4.Peer-Reviewed Original ResearchMeSH KeywordsAcute DiseaseAdolescentAdultAngioplasty, Balloon, CoronaryBenzenesulfonatesCalciumDouble-Blind MethodEchocardiographyHumansMaleMiddle AgedMuscle CellsMyocardial InfarctionMyocardial Reperfusion InjuryNecrosisPiperazinesRadiographyTomography, Emission-Computed, Single-PhotonVentricular Function, LeftConceptsPrimary percutaneous coronary interventionST-elevation myocardial infarctionLeft Ventricular SalvageElevation myocardial infarctionPlacebo-controlled clinical trialMCC-135Percutaneous coronary interventionIntracellular calcium overloadMyocardial infarctionPost-myocardial infarctionVentricular functionCalcium overloadEVOLVE studyCoronary interventionAdjunct therapyInfarct sizeClinical trialsPrimary PCIAcute ST-elevation myocardial infarctionMI studiesVentricular ejection fractionSerum cardiac markersAcute myocardial infarctionEarly clinical studiesMyocardial infarction size
2003
Use of radionuclide imaging in acute coronary syndromes
Abbott B, Wackers F. Use of radionuclide imaging in acute coronary syndromes. Current Cardiology Reports 2003, 5: 25-31. PMID: 12493157, DOI: 10.1007/s11886-003-0034-z.Peer-Reviewed Original ResearchConceptsAcute coronary syndromeMyocardial infarctionChest painCoronary syndromeEmergency departmentPerfusion imagingRadionuclide myocardial perfusion imagingAcute chest painTriage of patientsAcute myocardial infarctionPerfusion imaging studyMyocardial perfusion imagingNegative predictive valueReperfusion therapyED evaluationRoutine careRandomized trialsRisk stratificationInfarct sizePrognostic valueDiagnostic challengeUnnecessary hospitalizationPredictive valueTesting modalitiesImaging studies
2002
American Society of Nuclear Cardiology position statement on radionuclide imaging in patients with suspected acute ischemic syndromes in the emergency department or chest pain center
Wackers F, Brown K, Heller G, Kontos M, Tatum J, Udelson J, Ziffer J. American Society of Nuclear Cardiology position statement on radionuclide imaging in patients with suspected acute ischemic syndromes in the emergency department or chest pain center. Journal Of Nuclear Cardiology 2002, 9: 246-250. PMID: 11986573, DOI: 10.1067/mnc.2002.122630.Peer-Reviewed Original Research
1994
Radionuclide Evaluation of Coronary Artery Disease in the 1990S Choosing The Best Stress, Best Tracer, Best Technique
Wackers F. Radionuclide Evaluation of Coronary Artery Disease in the 1990S Choosing The Best Stress, Best Tracer, Best Technique. Cardiology Clinics 1994, 12: 385-389. PMID: 8033184, DOI: 10.1016/s0733-8651(18)30117-6.Peer-Reviewed Original Research
1990
Silent left ventricular dysfunction during routine activity after thrombolytic Therapy for acute myocardial infarction
Kayden D, Wackers F, Zaret B. Silent left ventricular dysfunction during routine activity after thrombolytic Therapy for acute myocardial infarction. Journal Of The American College Of Cardiology 1990, 15: 1500-1507. PMID: 2345230, DOI: 10.1016/0735-1097(90)92817-l.Peer-Reviewed Original ResearchConceptsTransient left ventricular dysfunctionLeft ventricular dysfunctionSilent left ventricular dysfunctionVentricular dysfunctionMyocardial infarctionCardiac eventsHospital dischargeEjection fractionThrombolytic therapySubmaximal supine bicycle exerciseNormal activityBaseline ejection fractionExercise test resultsSubsequent cardiac eventsSupine bicycle exerciseVentricular function monitoringAcute myocardial infarctionChest painPeak exerciseBicycle exerciseAmbulatory patientsElectrocardiographic changesPoor outcomePrognostic informationFunction monitoring
1981
Imaging the inflammatory response to acute myocardial infarction in man using indium-111-labeled autologous platelets.
Davies R, Thakur M, Berger H, Wackers F, Gottschalk A, Zaret B. Imaging the inflammatory response to acute myocardial infarction in man using indium-111-labeled autologous platelets. Circulation 1981, 63: 826-832. PMID: 7471338, DOI: 10.1161/01.cir.63.4.826.Peer-Reviewed Original ResearchConceptsMyocardial infarctionInflammatory responseIndium-111-labeled autologous plateletsMembrane-active antiarrhythmic drugsPeak serum creatine kinaseStable coronary artery diseaseAcute transmural myocardial infarctionPeripheral leukocyte countCoronary artery diseaseAcute myocardial infarctionHours of infarctionTransmural myocardial infarctionIncidence of pericarditisLocation of infarctionIndium-111 leukocytesSerum creatine kinaseChest painArtery diseaseAntiarrhythmic drugsAcute infarctionAutologous leukocytesLeukocyte countAntiinflammatory drugsAutologous plateletsInfarction
1978
Thallium-201 myocardial imaging: an interinstitutional study of observer variability.
Trobaugh G, Wackers F, Sokole E, DeRouen T, Ritchie J, Hamilton G. Thallium-201 myocardial imaging: an interinstitutional study of observer variability. Journal Of Nuclear Medicine 1978, 19: 359-63. PMID: 632921.Peer-Reviewed Original Research
1976
Myocardial scintigraphy in patients with acute and chronic coronary insufficiency.
Wackers F, Sokole-Busemann E, Samson G, van der Schoot J, Lie K, Liem K, Durrer D, Wellens H. Myocardial scintigraphy in patients with acute and chronic coronary insufficiency. Nederlands Tijdschrift Voor Geneeskunde 1976, 120: 2151-6. PMID: 1012373.Peer-Reviewed Original ResearchCoronary artery disease in patients dying from cardiogenic shock or congestive heart failure in the setting of acute myocardial infarction.
Wackers F, Lie K, Becker A, Durrer D, Wellens H. Coronary artery disease in patients dying from cardiogenic shock or congestive heart failure in the setting of acute myocardial infarction. Heart 1976, 38: 906. PMID: 971375, PMCID: PMC483104, DOI: 10.1136/hrt.38.9.906.Peer-Reviewed Original ResearchConceptsCongestive heart failureAcute myocardial infarctionHeart failureCardiogenic shockCoronary arteryMyocardial infarctionSevere diseaseFatal congestive heart failureRefractory congestive heart failurePump failureThree-vessel diseaseCoronary bypass surgeryRight coronary arteryCoronary artery diseaseLeft circumflex arteryCent narrowingBypass surgeryArtery diseaseLeft anteriorCircumflex arteryPathological findingsSevere narrowingEqual incidenceAnatomical findingsPatientsMyocardial imaging in coronary heart disease with radionuclides, with emphasis on Thallium-201.
Wackers F, Sokole E, Samson G, Schoot J, Wellens H. Myocardial imaging in coronary heart disease with radionuclides, with emphasis on Thallium-201. International Journal Of Cardiology 1976, 4: 273-82. PMID: 183959.Peer-Reviewed Original ResearchValue and Limitations of Thallium-201 Scintigraphy in the Acute Phase of Myocardial Infarction
Wackers F, Sokole E, Samson G, Schoot J, Lie K, Liem K, Wellens H. Value and Limitations of Thallium-201 Scintigraphy in the Acute Phase of Myocardial Infarction. New England Journal Of Medicine 1976, 295: 1-5. PMID: 1272283, DOI: 10.1056/nejm197607012950101.Peer-Reviewed Original Research
1975
Noninvasive visualization of acute myocardial infarction in man with thallium-201.
Wackers F, Schoot J, Sokole E, Samson G, Niftrik G, Lie K, Durrer D, Wellens H. Noninvasive visualization of acute myocardial infarction in man with thallium-201. Heart 1975, 37: 741. PMID: 1156481, PMCID: PMC482866, DOI: 10.1136/hrt.37.7.741.Peer-Reviewed Original Research