2015
Multimodality therapy for locally advanced thymomas: A propensity score–matched cohort study from the European Society of Thoracic Surgeons Database
Leuzzi G, Rocco G, Ruffini E, Sperduti I, Detterbeck F, Weder W, Venuta F, Van Raemdonck D, Thomas P, Facciolo F, Group E. Multimodality therapy for locally advanced thymomas: A propensity score–matched cohort study from the European Society of Thoracic Surgeons Database. Journal Of Thoracic And Cardiovascular Surgery 2015, 151: 47-57.e1. PMID: 26403869, DOI: 10.1016/j.jtcvs.2015.08.034.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgedAged, 80 and overAsiaChemotherapy, AdjuvantChildChi-Square DistributionDatabases, FactualDisease ProgressionDisease-Free SurvivalEuropeFemaleHumansKaplan-Meier EstimateMaleMiddle AgedMultivariate AnalysisNeoadjuvant TherapyNeoplasm Recurrence, LocalNeoplasm StagingNorth AmericaPropensity ScoreProportional Hazards ModelsRadiotherapy, AdjuvantRetrospective StudiesRisk AssessmentRisk FactorsSocieties, MedicalThymectomyThymomaThymus NeoplasmsTime FactorsTreatment OutcomeTumor BurdenYoung AdultConceptsRelapse-free survivalAdvanced thymomaMultimodality therapyOverall survivalT classificationPropensity score-matched cohort studyMultivariate Cox proportional hazards modelPropensity score-matched analysisCox proportional hazards modelPathologic T classificationStage III thymomaThoracic Surgeons databaseSignificant survival advantageSpecific pathologic featuresStrong predictive factorProportional hazards modelInduction therapyAdjuvant therapyPT3 tumorsCohort studyIndependent predictorsPrognostic impactMultivariable analysisPathologic featuresPredictive factors
2014
Outcome of primary neuroendocrine tumors of the thymus: A joint analysis of the International Thymic Malignancy Interest Group and the European Society of Thoracic Surgeons databases
Filosso PL, Yao X, Ahmad U, Zhan Y, Huang J, Ruffini E, Travis W, Lucchi M, Rimner A, Antonicelli A, Guerrera F, Detterbeck F, Committee E. Outcome of primary neuroendocrine tumors of the thymus: A joint analysis of the International Thymic Malignancy Interest Group and the European Society of Thoracic Surgeons databases. Journal Of Thoracic And Cardiovascular Surgery 2014, 149: 103-109.e2. PMID: 25308116, DOI: 10.1016/j.jtcvs.2014.08.061.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAged, 80 and overChemotherapy, AdjuvantDatabases, FactualFemaleHumansKaplan-Meier EstimateMaleMiddle AgedMultivariate AnalysisNeoadjuvant TherapyNeoplasm GradingNeoplasm Recurrence, LocalNeoplasm StagingNeuroendocrine TumorsProportional Hazards ModelsRadiotherapy, AdjuvantRetrospective StudiesRisk FactorsThymectomyThymus NeoplasmsTime FactorsTreatment OutcomeYoung AdultConceptsInternational Thymic Malignancy Interest GroupMasaoka-Koga stageOverall survivalCompleteness of resectionPrimary neuroendocrine tumorThoracic Surgeons databasePrognostic factorsHistologic subtypeSurgeons databaseNeuroendocrine tumorsHigher biologic aggressivenessMasaoka-Koga stage ICommon histologic subtypeMedian overall survivalEuropean SocietyRetrospective multicenter studyKaplan-Meier methodStrong prognostic factorLog-rank testInduction therapyAdjuvant treatmentCumulative incidenceResection statusComplete resectionMulticenter studyTumours of the thymus: a cohort study of prognostic factors from the European Society of Thoracic Surgeons database
Ruffini E, Detterbeck F, Van Raemdonck D, Rocco G, Thomas P, Weder W, Brunelli A, Evangelista A, Venuta F, Khaled A, Arame A, Refai M, Casadio C, Carbognani P, Cerfolio R, Donati G, Foroulis C, Gebitekin C, de Antonio D, Kernstine K, Keshavjee S, Moser B, Lequaglie C, Liberman M, Lim E, Nicholson A, Lang-Lazdunski L, Mancuso M, Altorki N, Nosotti M, Novoa N, Brioude G, Oliaro A, Filosso P, Saita S, Scarci M, Schützner J, Terzi A, Toker A, Van Veer H, Anile M, Rendina E, Voltolini L, Zurek W. Tumours of the thymus: a cohort study of prognostic factors from the European Society of Thoracic Surgeons database. European Journal Of Cardio-Thoracic Surgery 2014, 46: 361-368. PMID: 24482389, PMCID: PMC4155438, DOI: 10.1093/ejcts/ezt649.Peer-Reviewed Original ResearchConceptsOverall survivalAdjuvant therapyIncomplete resectionComplete resectionThymic tumorsTumor sizeWorld Health Organization histologyTen-year OSDisease-free survivalEuropean SocietyType of resectionClinical pathological characteristicsRisk of recurrenceShorter overall survivalThoracic Surgeons databaseR0 resectionCohort studyCumulative incidenceSecondary outcomesImproved survivalPrimary outcomePrognostic factorsIncident casesPrognostic predictorSurgeons databaseFewer complications result from a video-assisted approach to anatomic resection of clinical stage I lung cancer
Boffa DJ, Dhamija A, Kosinski AS, Kim AW, Detterbeck FC, Mitchell JD, Onaitis MW, Paul S. Fewer complications result from a video-assisted approach to anatomic resection of clinical stage I lung cancer. Journal Of Thoracic And Cardiovascular Surgery 2014, 148: 637-643. PMID: 24529729, DOI: 10.1016/j.jtcvs.2013.12.045.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgedAged, 80 and overFemaleHumansLogistic ModelsLung NeoplasmsMaleMiddle AgedMultivariate AnalysisNeoplasm StagingOdds RatioPneumonectomyPostoperative ComplicationsPropensity ScoreRisk FactorsThoracic Surgery, Video-AssistedThoracotomyTime FactorsTreatment OutcomeYoung AdultConceptsStage I lung cancerClinical stage I lung cancerI lung cancerThoracic Surgeons databaseAnatomic resectionLung cancerSurgeons databaseStage I primary lung cancerVideo-assisted thoracic surgery approachEarly-stage lung cancerMore pulmonary complicationsClinical stage ILung cancer resectionPrimary lung cancerMorbidity of patientsThoracic surgery approachStage lung cancerStandard of careMorbidity of thoracotomyVideo-assisted approachLower mortality rateOverall complicationsPulmonary complicationsThoracotomy groupVATS cohort