1985
Pulmonary macrophage function during experimental cytomegalovirus interstitial pneumonia
Miller S, Bia F, Coleman D, Lucia H, Young K, Root R. Pulmonary macrophage function during experimental cytomegalovirus interstitial pneumonia. Infection And Immunity 1985, 47: 211-216. PMID: 2981196, PMCID: PMC261498, DOI: 10.1128/iai.47.1.211-216.1985.Peer-Reviewed Original ResearchConceptsPulmonary macrophagesInterstitial pneumoniaCytomegalovirus interstitial pneumoniaMacrophage oxidative functionTissue culture infective dosesH2O2 releaseCMV interstitial pneumoniaPulmonary macrophage functionGuinea pig CMVSalivary gland suspensionsBuffy coat cellsBone marrow cellsPhorbol myristate acetateO2 consumptionCMV pneumoniaPulmonary granulocytesCytomegalovirus infectionVariety of pathogensWhole lungControl animalsPulmonary lavageUninfected controlsMacrophage functionVirus isolationDay 7
1983
Cytomegaloviral Infections in the Guinea Pig: Experimental Models for Human Disease
Bia F, Griffith B, Fong C, Hsiung G. Cytomegaloviral Infections in the Guinea Pig: Experimental Models for Human Disease. Clinical Infectious Diseases 1983, 5: 177-195. PMID: 6302812, DOI: 10.1093/clinids/5.2.177.Peer-Reviewed Original ResearchConceptsGuinea pig cytomegalovirusInterstitial pneumoniaTransplacental transmissionGuinea pigsPrimary CMV infectionPolymorphonuclear leukocyte functionGuinea pig modelSalivary gland virusHuman viral infectionsCongenital infectionCytomegaloviral infectionCMV infectionBlood transfusionFungal superinfectionsViremic infectionAntigen vaccineTransmission of virusesSuch vaccinesLeukocyte functionHuman diseasesCocultivation techniquesViral infectionPig modelCytomegalovirusInfectious diseases
1982
Effects of Vaccination on Cytomegalovirus-Associated Interstitial Pneumonia in Strain 2 Guinea Pigs
Bia F, Lucia H, Fong C, Tarsio M, Hsiung G. Effects of Vaccination on Cytomegalovirus-Associated Interstitial Pneumonia in Strain 2 Guinea Pigs. The Journal Of Infectious Diseases 1982, 145: 742-747. PMID: 6281341, DOI: 10.1093/infdis/145.2.742.Peer-Reviewed Original ResearchConceptsStrain 2 guinea pigsInterstitial pneumoniaCMV infectionGuinea pigsMinimal histopathologic changesTissue culture infective dosesBilateral interstitial pneumoniaEffect of vaccinationStudy of pathogenesisGuinea pig cytomegalovirusHistologic evidenceHistopathologic changesPneumoniaVaccinated animalsInfective dosesCytomegalovirusInfectionLungInfected tissuesPathogenesisPigsTissuePreventionAnimalsViremia