2017
Surgical outcome in adolescents with mesial temporal sclerosis: Is it different?
Farooque P, Hirsch L, Levy S, Testa F, Mattson R, Spencer D. Surgical outcome in adolescents with mesial temporal sclerosis: Is it different? Epilepsy & Behavior 2017, 69: 24-27. PMID: 28235653, DOI: 10.1016/j.yebeh.2016.10.028.Peer-Reviewed Original ResearchConceptsMesial temporal sclerosisTemporal sclerosisStatus epilepticusTemporal lobectomySurgical outcomesAdolescent patientsIctal onsetMore lobesEpilepsy surgery databaseScalp EEGSeizure freedomPatient populationSurgery DatabaseRisk factorsPatientsElectrographic dataLobectomyEpilepticusTwo yearsSclerosisHypometabolismNovel findingsAdolescentsMRIOutcomes
2014
Complete remission of childhood-onset epilepsy: stability and prediction over two decades
Berg AT, Rychlik K, Levy SR, Testa FM. Complete remission of childhood-onset epilepsy: stability and prediction over two decades. Brain 2014, 137: 3213-3222. PMID: 25338950, PMCID: PMC4240301, DOI: 10.1093/brain/awu294.Peer-Reviewed Original ResearchConceptsComplete remissionSeizure resolutionSeizure outcomeInitial diagnosisChildhood epilepsyLast contactCourse of epilepsyChildhood-onset epilepsySelf-limited epilepsy syndromeProportional hazards modelProspective cohortBaseline factorsRelapse rateLate remissionEpilepsy syndromesComplete resolutionRemissionHazards modelPredictive valueEpilepsyLogistic regressionConnecticut StudyDiagnosisFurther treatmentDevelopmental problemsLong‐term seizure remission in childhood absence epilepsy: Might initial treatment matter?
Berg AT, Levy SR, Testa FM, Blumenfeld H. Long‐term seizure remission in childhood absence epilepsy: Might initial treatment matter? Epilepsia 2014, 55: 551-557. PMID: 24512528, PMCID: PMC3999182, DOI: 10.1111/epi.12551.Peer-Reviewed Original ResearchConceptsChildhood absence epilepsyComplete remissionAtypical EEG featuresValproic acidEarly remissionAbsence epilepsyLong-term seizure outcomeLong-term seizure remissionPotential disease-modifying effectsPrimary long-term outcomeCommunity-based cohort studySignificant imaging abnormalitiesDisease-modifying effectsInitial treatment choiceLong-term outcomesInitial success rateGenetic absence modelSupporting Information sectionSeizure outcomeCohort studyFirst medicationSeizure remissionConvulsive seizuresImaging abnormalitiesInitial medication
2012
Age at onset of epilepsy, pharmacoresistance, and cognitive outcomes
Berg AT, Zelko FA, Levy SR, Testa FM. Age at onset of epilepsy, pharmacoresistance, and cognitive outcomes. Neurology 2012, 79: 1384-1391. PMID: 22972641, PMCID: PMC3448745, DOI: 10.1212/wnl.0b013e31826c1b55.Peer-Reviewed Original Research