2020
Comparative Genomics within and across Bilaterians Illuminates the Evolutionary History of ALK and LTK Proto-Oncogene Origination and Diversification
Dornburg A, Wang Z, Wang J, Mo ES, López-Giráldez F, Townsend JP. Comparative Genomics within and across Bilaterians Illuminates the Evolutionary History of ALK and LTK Proto-Oncogene Origination and Diversification. Genome Biology And Evolution 2020, 13: evaa228. PMID: 33196781, PMCID: PMC7851593, DOI: 10.1093/gbe/evaa228.Peer-Reviewed Original ResearchConceptsLeukocyte tyrosine kinaseEvolutionary historyPhylogenetic analysisProtein-coding genesComparative genomic analysisEarly embryonic expressionMetazoan genomesComparative genomicsPhylogenetic contextModel organismsEmbryonic expressionModel speciesHuman genesKey genesGenomic analysisImportant genesMammal systemsFunctional convergenceTyrosine kinaseMolecular homologyGenesFunctional roleVertebratesMammal modelsHomology
2013
Evaluating Phylogenetic Informativeness as a Predictor of Phylogenetic Signal for Metazoan, Fungal, and Mammalian Phylogenomic Data Sets
López-Giráldez F, Moeller AH, Townsend JP. Evaluating Phylogenetic Informativeness as a Predictor of Phylogenetic Signal for Metazoan, Fungal, and Mammalian Phylogenomic Data Sets. BioMed Research International 2013, 2013: 621604. PMID: 23878813, PMCID: PMC3708382, DOI: 10.1155/2013/621604.Peer-Reviewed Original ResearchConceptsPhylogenomic data setsPhylogenetic informativenessPhylogenetic signalEffects of homoplasyPoor phylogenetic resolutionPhylogenetic resolutionSister cladeOutgroup taxaPhylogenetic researchTaxonomic groupsPhylogenetic inferenceAdvantageous genesGenesMetazoansCladeTaxaDiverse groupDiverse time scalesHomoplasyHaphazard samplingMammalsFungiOrganismsFungalMarkers
2011
Assessing the Role of Tandem Repeats in Shaping the Genomic Architecture of Great Apes
Farré M, Bosch M, López-Giráldez F, Ponsà M, Ruiz-Herrera A. Assessing the Role of Tandem Repeats in Shaping the Genomic Architecture of Great Apes. PLOS ONE 2011, 6: e27239. PMID: 22076140, PMCID: PMC3208591, DOI: 10.1371/journal.pone.0027239.Peer-Reviewed Original ResearchConceptsEvolutionary breakpoint regionsTandem repeatsEvolutionary regionBreakpoint regionSpecific tandem repeatMore base pairsGreat apesGenome architectureMammalian genomesGenome organizationSynteny blocksChromatin conformationEvolutionary biologistsGenomic architectureAncestral reconstructionGenome instabilityMacaque genomeChromosomal reorganizationTransposable elementsGenomic regionsHuman genomeGenomic areasAlu elementsGenomeBase pairs
2006
Analyses of carnivore microsatellites and their intimate association with tRNA-derived SINEs
López-Giráldez F, Andrés O, Domingo-Roura X, Bosch M. Analyses of carnivore microsatellites and their intimate association with tRNA-derived SINEs. BMC Genomics 2006, 7: 269. PMID: 17059596, PMCID: PMC1634856, DOI: 10.1186/1471-2164-7-269.Peer-Reviewed Original Research