Fangbai (Janet) Sun, MPH
BiostatisticianCards
About
Research
Publications
2024
A re-look at the relevance of TSH and thyroid autoimmunity for pregnancy outcomes: Analyses of RCT data from PPCOS II and AMIGOS
Kuokkanen S, Seungdamrong A, Santoro N, Lieman H, Sun F, Wild R, Zhang H, Pal L. A re-look at the relevance of TSH and thyroid autoimmunity for pregnancy outcomes: Analyses of RCT data from PPCOS II and AMIGOS. Fertility And Sterility 2024 PMID: 39672366, DOI: 10.1016/j.fertnstert.2024.12.005.Peer-Reviewed Original ResearchThyroid-stimulating hormoneRandomized controlled trialsTPO-AbThyroid autoimmunityPregnancy outcomesAssessment of Multiple Intrauterine GestationsRetrospective cohort analysis of dataRisk of pregnancy lossEarly preterm birthMaternal TSH levelsThyroid peroxidase antibodyCohort analysis of dataRetrospective cohort analysisBody mass indexDuration of infertilityAnalysis of RCT dataPolycystic ovary syndromeIntrauterine gestationPreterm birthTSH levelsPeroxidase antibodiesOvarian stimulationLive birthsPPCOS IIStimulating hormoneIS HISTORY OF POLYCYSTIC OVARY SYNDROME (PCOS) RELATED TO SLEEP QUALITY IN POSTMENOPAUSAL WOMEN IN THE STUDY OF WOMEN’S HEALTH ACROSS THE NATION
Alur-Gupta S, Sun F, Zhang H, Derby C, Kravitz H, Neal-Perry G, Swanson L, Vitek W, Santoro N, Sammel M. IS HISTORY OF POLYCYSTIC OVARY SYNDROME (PCOS) RELATED TO SLEEP QUALITY IN POSTMENOPAUSAL WOMEN IN THE STUDY OF WOMEN’S HEALTH ACROSS THE NATION. Fertility And Sterility 2024, 122: e419. DOI: 10.1016/j.fertnstert.2024.08.262.Peer-Reviewed Original ResearchASSISTED REPRODUCTIVE TECHNOLOGY USE AND OTHER BASELINE CHARACTERISTICS IMPACT THE ACCEPTABILITY OF TREATMENT FOR PREGNANCY OF UNKNOWN LOCATION: SECONDARY ANALYSIS OF THE ACTORNOT TRIAL
Ayyar A, Kloos J, Sun F, Zhang H, Weinerman R, Barnhart K. ASSISTED REPRODUCTIVE TECHNOLOGY USE AND OTHER BASELINE CHARACTERISTICS IMPACT THE ACCEPTABILITY OF TREATMENT FOR PREGNANCY OF UNKNOWN LOCATION: SECONDARY ANALYSIS OF THE ACTORNOT TRIAL. Fertility And Sterility 2024, 122: e104. DOI: 10.1016/j.fertnstert.2024.07.1003.Peer-Reviewed Original ResearchThe effect of improved metabolic syndrome parameters on live birth
Spitzer T, Diamond M, Wild R, Legro R, Zhang H, Sun F, Ling S, Santoro N. The effect of improved metabolic syndrome parameters on live birth. Fertility And Sterility 2024, 122: 373-375. PMID: 38641159, DOI: 10.1016/j.fertnstert.2024.04.020.Peer-Reviewed Original ResearchMetabolic syndrome Z-scoreLifestyle interventionLive birthsLive birth rateMetabolic syndrome parametersZ-scoreMetabolic syndromeUnexplained infertilityIntrauterine inseminationOvarian stimulationSyndrome parametersMetabolic parametersObese WomenBirth outcomesLive birth outcomesIntervention phaseImprove metabolic syndromeSecondary analysisFisher's exact testStudy participantsZ-score differenceLifestyle modificationStudent's t-testBirth rateLogistic regression
2023
Moderate and increased physical activity is not detrimental to live birth rates among women with unexplained infertility and obesity
Vitek W, Sun F, Cardozo E, Hoeger K, Hansen K, Santoro N, Zhang H, Legro R. Moderate and increased physical activity is not detrimental to live birth rates among women with unexplained infertility and obesity. F&S Reports 2023, 4: 308-312. PMID: 37719091, PMCID: PMC10504528, DOI: 10.1016/j.xfre.2023.06.004.Peer-Reviewed Original ResearchLive birth rateSteps/dayPhysical activityInfertility trialsLifestyle modificationUnexplained infertilityObese womenBirth rateClomiphene citrate treatmentUS fertility centersClinical pregnancy rateLifestyle modification programTime of enrollmentModerate physical activityPhysical activity goalsMiscarriage rateFertility centerIntrauterine inseminationFitbit activity trackerPregnancy rateSecondary analysisCitrate treatmentActivity goalsModification programWomenAnti-Müllerian Hormone Level Decline in Patients Undergoing Hysterectomy With and Without Oophorectomy Compared With Natural Menopause
Santoro N, Flyckt R, Davis A, Finkelstein J, Crawford S, Sun F, Derby C, Morrison A, Sluss P, Zhang H. Anti-Müllerian Hormone Level Decline in Patients Undergoing Hysterectomy With and Without Oophorectomy Compared With Natural Menopause. Obstetrics And Gynecology 2023, 141: 331-340. PMID: 36649324, PMCID: PMC9858351, DOI: 10.1097/aog.0000000000005049.Peer-Reviewed Original ResearchConceptsFinal menstrual periodAnti-Müllerian hormone levelsAMH levelsNatural menopauseHormone levelsUndetectable AMH levelsCommunity-based studyOvarian conservationOvarian reserveAMH measurementOvarian failureMenstrual periodSurgery dateHysterectomyLinear mixed modelingMenopauseSurvival analysisPatientsImmediate reductionMixed modelingWomenOvariesSimilar patternRapid declineBSO
2022
Minimal Stimulation Using Gonadotropin-Releasing Hormone Antagonist is Associated with Higher Live Birth Rates: A National Study of 13,050 Cycles
Hurley E, Sun F, Zhang H, Polotsky A, Rios J. Minimal Stimulation Using Gonadotropin-Releasing Hormone Antagonist is Associated with Higher Live Birth Rates: A National Study of 13,050 Cycles. Women's Health Reports 2022, 3: 957-963. PMID: 36479370, PMCID: PMC9712044, DOI: 10.1089/whr.2022.0080.Peer-Reviewed Original ResearchHigher live birth rateLive birth rateGnRH antagonist useAntagonist useMinimal stimulationRank sum testHormone antagonistBirth rateImproved live birth ratesGonadotropin-releasing hormone antagonistCancelation rateCycle cancelation rateGnRH antagonist suppressionMinimal stimulation IVFTotal gonadotropin dosageDiminished ovarian reserveYears of ageWilcoxon rank sum testChi-square testNumber of embryosGonadotropin dosageOvarian reserveGnRH antagonistAntimullerian hormoneOlder womenRELATIONSHIP OF ANTITHYROID ANTIBODIES AND TSH TO INFERTILITY PHENOTYPES AND OUTCOMES
Seungdamrong A, Pal L, Kuokkanen S, Lieman H, Wild R, Sun F, Zhang H, Diamond M, Legro R, Santoro N. RELATIONSHIP OF ANTITHYROID ANTIBODIES AND TSH TO INFERTILITY PHENOTYPES AND OUTCOMES. Fertility And Sterility 2022, 118: e103. DOI: 10.1016/j.fertnstert.2022.08.311.Peer-Reviewed Original ResearchPoor reproducibility of percentage of normally shaped sperm using the World Health Organization Fifth Edition strict grading criteria
Baker KC, Steiner AZ, Hansen KR, Barnhart KT, Cedars MI, Legro RS, Diamond MP, Krawetz SA, Usadi R, Baker VL, Coward RM, Sun F, Wild R, Masson P, Smith JF, Santoro N, Zhang H, Network R. Poor reproducibility of percentage of normally shaped sperm using the World Health Organization Fifth Edition strict grading criteria. F&S Reports 2022, 3: 110-115. PMID: 35789726, PMCID: PMC9250115, DOI: 10.1016/j.xfre.2022.03.003.Peer-Reviewed Original ResearchFertility centerCore laboratoryStrict morphologySecondary cohort analysisPlacebo-controlled trialSame semen sampleMultisite clinical trialLower reference limitSemen samplesInfertility trialsClinical trialsFertility laboratoriesCohort analysisCutoff valueEffect of antioxidantsReference limitsInterobserver agreementCentral laboratoryModerate agreementSemen valuesLack of correlationTrialsGrading criteriaMale fertilityCenter LaboratoryBiomarkers of Stress and Male Fertility
Spitzer TL, Trussell JC, Coward RM, Hansen KR, Barnhart KT, Cedars MI, Diamond MP, Krawetz SA, Sun F, Zhang H, Santoro N, Steiner AZ. Biomarkers of Stress and Male Fertility. Reproductive Sciences 2022, 29: 1262-1270. PMID: 35106743, PMCID: PMC9078052, DOI: 10.1007/s43032-022-00853-x.Peer-Reviewed Original ResearchConceptsLive birth rateSemen parametersSalivary levelsSperm countPregnancy/live birth rateBirth rateTotal motile sperm countMale factor infertilityMotile sperm countDNA fragmentationTotal sperm countSalivary cortisol levelsMale fertilityStress-related biomarkersChi-square testingSalivary alpha-amylaseInfertility trialsCohort studyHighest quintileIntrauterine inseminationPregnancy rateUpper quintileInfertile menPhysiologic measuresBiomarkers of stress