Featured Publications
Prevalence of and risk factors for vertebral fracture and low bone mineral density among Peruvian women aging with HIV
Cabrera D, Cornejo M, Slotkin R, Pinedo Y, Yu W, Guan W, Garcia P, Hsieh E. Prevalence of and risk factors for vertebral fracture and low bone mineral density among Peruvian women aging with HIV. Archives Of Osteoporosis 2023, 18: 64. PMID: 37160770, PMCID: PMC10170032, DOI: 10.1007/s11657-023-01250-w.Peer-Reviewed Original ResearchConceptsBone mineral densityLow bone mineral densityThoracolumbar X-rayVertebral fracturesFemoral neckRisk factorsLumbar spineOsteoporosis treatmentTotal hipTreatment gapMineral densityTotal hip bone mineral densityPresence of VFsPeruvian womenTH bone mineral densityHip bone mineral densityFN bone mineral densityLower FN BMDSubset of patientsGenant semiquantitative methodLower femoral neckImportant treatment gapsKey risk factorsAntiretroviral therapyFRAX score
2021
Incident Rheumatoid Arthritis in HIV Infection: Epidemiology and Treatment
Hanberg JS, Hsieh E, Akgün KM, Weinstein E, Fraenkel L, Justice AC, Team T. Incident Rheumatoid Arthritis in HIV Infection: Epidemiology and Treatment. Arthritis & Rheumatology 2021, 73: 2189-2199. PMID: 34042306, DOI: 10.1002/art.41802.Peer-Reviewed Original ResearchConceptsDisease-modifying antirheumatic drugsIncident rheumatoid arthritisDiagnosis of RARA patientsRheumatoid arthritisRheumatoid factorUninfected individualsRheumatology/European AllianceHigh titersVeterans Aging Cohort StudyRA-specific autoantibodiesRheumatology 2010 criteriaTenth Revision codesAging Cohort StudyIncidence rate ratiosHigh autoantibody titersICD-10 codesDMARD useUninfected veteransAntirheumatic drugsAutoantibody titersCohort studyImmunosuppressed populationHIV infectionMedical chartsEarly experience of COVID-19 vaccination in adults with systemic rheumatic diseases: results from the COVID-19 Global Rheumatology Alliance Vaccine Survey
Sattui SE, Liew JW, Kennedy K, Sirotich E, Putman M, Moni TT, Akpabio A, Alpízar-Rodríguez D, Berenbaum F, Bulina I, Conway R, Singh AD, Duff E, Durrant KL, Gheita TA, Hill CL, Howard RA, Hoyer BF, Hsieh E, Kibbi L, Kilian A, Kim AH, Liew DFL, Lo C, Miller B, Mingolla S, Nudel M, Palmerlee CA, Singh JA, Singh N, Ugarte-Gil MF, Wallace J, Young KJ, Bhana S, Costello W, Grainger R, Machado PM, Robinson PC, Sufka P, Wallace ZS, Yazdany J, Harrison C, Larché M, Levine M, Foster G, Thabane L, Rider LG, Hausmann JS, Simard JF, Sparks JA. Early experience of COVID-19 vaccination in adults with systemic rheumatic diseases: results from the COVID-19 Global Rheumatology Alliance Vaccine Survey. RMD Open 2021, 7: e001814. PMID: 34493645, PMCID: PMC8424419, DOI: 10.1136/rmdopen-2021-001814.Peer-Reviewed Original ResearchConceptsDisease-modifying antirheumatic drugsPatient-reported adverse eventsSystemic rheumatic diseasesCOVID-19 vaccinationRheumatic disease flareRheumatic diseasesDisease flareCOVID-19 vaccineAdverse eventsVaccine efficacyMuscle/joint painJanssen/JohnsonTime of vaccinationFever/chillsCommon rheumatic diseasePatient-reported dataOxford/AstraZenecaEarly experienceVaccines surveyAntirheumatic drugsMedication changesJoint painMost patientsPfizer-BioNTechRheumatoid arthritisSocial Support for Self-Care: Patient Strategies for Managing Diabetes and Hypertension in Rural Uganda
Tusubira AK, Nalwadda CK, Akiteng AR, Hsieh E, Ngaruiya C, Rabin TL, Katahoire A, Hawley NL, Kalyesubula R, Ssinabulya I, Schwartz JI, Armstrong-Hough M. Social Support for Self-Care: Patient Strategies for Managing Diabetes and Hypertension in Rural Uganda. Annals Of Global Health 2021, 87: 86. PMID: 34458110, PMCID: PMC8378074, DOI: 10.5334/aogh.3308.Peer-Reviewed Original ResearchConceptsNon-communicable diseasesSelf-care practicesPrescribed medicinesConventional medicinePatient's social support networkRural UgandaSelf-care activitiesBlood sugar levelsCross-sectional qualitative studyResource-limited settingsSelf-care effortsSocial support networksSocial supportNCD clinicsNineteen patientsAdult patientsHealth facilitiesPatientsPatient strategiesManaging diabetesHypertensionSelf-CareDiabetesDiagnostic testsLow-income countriesValidation of a six-item dietary calcium screening tool among HIV patients in China
Tseng LY, Xie W, Pan W, Lyu H, Yu Z, Shi W, He Y, Chen W, Li T, Hsieh E. Validation of a six-item dietary calcium screening tool among HIV patients in China. Public Health Nutrition 2021, 24: 4786-4795. PMID: 33820577, PMCID: PMC8600937, DOI: 10.1017/s1368980021001427.Peer-Reviewed Original ResearchConceptsSix-item toolAdjacent quartilesClinical practiceScreening toolClinical risk factorsFollow-up screeningModerate relative validityTime-point studyHIV patientsAverage BMIBone healthMean ageOutpatient settingNutritional assessmentRisk factorsRoutine screeningDietary CaHealthy dietDisease preventionHIVFurther assessmentRelative validityAdequate CaChinese individualsTarget populationLong-term trabecular bone score and bone mineral density changes in Chinese antiretroviral-treated HIV-infected individuals
Guan W, Pan W, Yu W, Cao W, Lin Q, Zhang Z, Song X, Li Y, Tian J, Xu Y, Li T, Hsieh E. Long-term trabecular bone score and bone mineral density changes in Chinese antiretroviral-treated HIV-infected individuals. Archives Of Osteoporosis 2021, 16: 41. PMID: 33624129, PMCID: PMC9675940, DOI: 10.1007/s11657-021-00890-0.Peer-Reviewed Original ResearchConceptsTrabecular bone scoreBone mineral densityTH bone mineral densityNormal bone mineral densityAntiretroviral therapyBone scoreART initiationFemoral neckMineral densityBone microarchitectureTotal hip (TH) BMDLumbar spine (LS) BMDBone mineral density changesFN bone mineral densityLarge tertiary care hospitalRetrospective chart reviewTertiary care hospitalMineral density changesMean percent decreaseResultsFour hundred fiftyPercent decreaseAdult PWHChart reviewCare hospitalBMD changesKnowledge and Impact of COVID-19 on Middle-Aged and Older People Living with HIV in Lima, Peru
Diaz MM, Cabrera DM, Gil-Zacarias M, Ramirez V, Saavedra M, Cárcamo C, Hsieh E, Garcia PJ. Knowledge and Impact of COVID-19 on Middle-Aged and Older People Living with HIV in Lima, Peru. Journal Of The International Association Of Providers Of AIDS Care (JIAPAC) 2021, 20: 23259582211056760. PMID: 34870508, PMCID: PMC8655474, DOI: 10.1177/23259582211056760.Peer-Reviewed Original ResearchConceptsLow educational levelCOVID-19Large HIV clinicMajority of PWHCross-sectional telephone surveyHealthcare systemCOVID-19 symptomsHealth impactsHigher COVID-19 case ratesEducational levelMental health impactCOVID-19 case ratesHIV clinicOlder PWHFemale sexRisk factorsPWHMedical careCase ratesNationwide quarantineOlder peopleVulnerable populationsTelephone surveySocioeconomic supportHIV
2020
Longitudinal change in bone mineral density among Chinese individuals with HIV after initiation of antiretroviral therapy
Guo F, Song X, Li Y, Guan W, Pan W, Yu W, Li T, Hsieh E. Longitudinal change in bone mineral density among Chinese individuals with HIV after initiation of antiretroviral therapy. Osteoporosis International 2020, 32: 321-332. PMID: 32803316, PMCID: PMC9509525, DOI: 10.1007/s00198-020-05584-w.Peer-Reviewed Original ResearchConceptsTenofovir disoproxil fumarateLong-term clinical managementBone mineral density lossMineral density lossAntiretroviral therapyDisoproxil fumarateClinical managementRisk factorsGreater bone mineral density lossInitiation of TDFDual-energy x-ray absorptiometry testingHIV-specific parametersNon-TDF groupUndetectable viral loadOutpatient HIV clinicRelated risk factorsLarge tertiary hospitalBone mineral densityDensity lossAntiretroviral initiationTDF groupWeek 96HIV clinicWeek 48HIV diagnosisIncidence of hypertension among persons living with HIV in China: a multicenter cohort study
Fan H, Guo F, Hsieh E, Chen WT, Lv W, Han Y, Xie J, Li Y, Song X, Li T. Incidence of hypertension among persons living with HIV in China: a multicenter cohort study. BMC Public Health 2020, 20: 834. PMID: 32487185, PMCID: PMC7268367, DOI: 10.1186/s12889-020-08586-9.Peer-Reviewed Original ResearchConceptsIncidence of hypertensionAntiretroviral therapyChinese PLWHIncident hypertensionInitiation of ARTProspective longitudinal multicenter studyReceipt of ARTCox proportional hazards modelART-naïve patientsDetectable HIV viremiaMulticenter cohort studyCox regression analysisBody mass indexRecent viral loadLongitudinal multicenter studyProportional hazards modelHIV viremiaMedian followZidovudine exposureChronic comorbiditiesHIV careViral suppressionCohort studyConclusionsThe incidenceMass indexOptimizing Treatment for Adults with HIV/AIDS in China: Successes over Two Decades and Remaining Challenges
Cao W, Hsieh E, Li T. Optimizing Treatment for Adults with HIV/AIDS in China: Successes over Two Decades and Remaining Challenges. Current HIV/AIDS Reports 2020, 17: 26-34. PMID: 31939111, PMCID: PMC6989417, DOI: 10.1007/s11904-019-00478-x.BooksConceptsNational Free Antiretroviral Therapy ProgramAntiretroviral therapyHIV/AIDSChinese patientsFree antiretroviral therapy (ART) programLong-term antiretroviral therapyHIV/AIDS patientsFree antiretroviral drugsLifelong antiretroviral therapyHIV care cascadeAIDS/STD ControlAntiretroviral therapy coverageAntiretroviral therapy programsHIV/AIDS diagnosisHIV/AIDS treatmentNumber of patientsMulti-center studyAvailable ART regimensART regimensCare cascadeChronic complicationsAntiretroviral treatmentOverall mortalityAIDS patientsChronic inflammation
2019
Impact of reference point selection on DXA-based measurement of forearm bone mineral density
Yu W, Ying Q, Guan W, Lin Q, Zhang Z, Chen J, Engelke K, Hsieh E. Impact of reference point selection on DXA-based measurement of forearm bone mineral density. Archives Of Osteoporosis 2019, 14: 107. PMID: 31707587, PMCID: PMC9721067, DOI: 10.1007/s11657-019-0658-2.Peer-Reviewed Original Research
2017
Cardiovascular disease risk among Chinese antiretroviral-naïve adults with advanced HIV disease
Guo F, Hsieh E, Lv W, Han Y, Xie J, Li Y, Song X, Li T. Cardiovascular disease risk among Chinese antiretroviral-naïve adults with advanced HIV disease. BMC Infectious Diseases 2017, 17: 287. PMID: 28427339, PMCID: PMC5397830, DOI: 10.1186/s12879-017-2358-0.Peer-Reviewed Original ResearchConceptsCVD risk factorsFramingham risk scoreRisk factorsRisk scoreCVD riskAtherosclerotic cardiovascular disease risk scoreCommon CVD risk factorsCardiovascular disease risk scoreAdvanced HIV diseaseD risk scoreTreatment-naïve HIVLipid-lowering therapyPrevalence of hypertensionRisk factor treatmentBurden of CVDCardiovascular disease riskTreatment-naïve individualsMulticenter clinical trialAntiretroviral-naïve adultsDisease risk scoreRoutine clinical assessmentHIV providersAdverse eventsBackgroundCardiovascular diseaseHIV disease
2016
Longitudinal increase in vitamin D binding protein levels after initiation of tenofovir/lamivudine/efavirenz among individuals with HIV
Hsieh E, Fraenkel L, Han Y, Xia W, Insogna KL, Yin MT, Zhu T, Cheng X, Li T. Longitudinal increase in vitamin D binding protein levels after initiation of tenofovir/lamivudine/efavirenz among individuals with HIV. AIDS 2016, 30: 1935-1942. PMID: 27124896, PMCID: PMC4949136, DOI: 10.1097/qad.0000000000001131.Peer-Reviewed Original ResearchConceptsTenofovir disoproxil fumarateVitamin DProcollagen type 1 N-terminal propeptideInitiation of TDFTenofovir/lamivudine/efavirenzVitamin D binding protein (VDBP) levelsCollagen type 1 cross-linked C-telopeptideIntact parathyroid hormone levelsCross-linked C-telopeptideIntact parathyroid hormoneParathyroid hormone levelsTotal procollagen type 1 N-terminal propeptideBinding protein levelsProtein levelsMulticenter clinical trialPlasma samplesOngoing multicenter clinical trialsN-terminal propeptideClinical characteristicsParathyroid hormoneBone lossFormation markersDisoproxil fumarateC-telopeptideBone resorptionExploring HIV-related stigma among HIV-infected men who have sex with men in Beijing, China: a correlation study
Li Z, Hsieh E, Morano JP, Sheng Y. Exploring HIV-related stigma among HIV-infected men who have sex with men in Beijing, China: a correlation study. AIDS Care 2016, 28: 1394-1401. PMID: 27137205, PMCID: PMC5069196, DOI: 10.1080/09540121.2016.1179713.Peer-Reviewed Original ResearchConceptsHIV transmissionHIV stigmaStigma scoresPoor self-rated health statusBerger HIV Stigma ScaleSelf-rated health statusHIV-positive MSMIncidence of HIVMultivariable linear regression modelsHuman immunodeficiency virusLevels of HIVHIV Stigma ScaleAdverse health outcomesCross-sectional survey studySocial support networksAntiretroviral therapyHIV statusOpportunistic infectionsImmunodeficiency virusPoor adherenceSocio-demographic characteristicsRisk factorsStudy populationHIVHealth outcomes
2014
Osteoporosis knowledge, self-efficacy, and health beliefs among Chinese individuals with HIV
Hsieh E, Fraenkel L, Bradley EH, Xia W, Insogna KL, Cui Q, Li K, Li T. Osteoporosis knowledge, self-efficacy, and health beliefs among Chinese individuals with HIV. Archives Of Osteoporosis 2014, 9: 201. PMID: 25487753, PMCID: PMC4269230, DOI: 10.1007/s11657-014-0201-4.Peer-Reviewed Original ResearchConceptsHealth Belief ModelInternational Physical Activity QuestionnaireHealth beliefsPhysical activityPreventive behaviorsOsteoporosis Health Belief ScaleOsteoporosis Self-Efficacy ScaleVitamin D intakeClinical risk factorsDietary calcium intakeBelief ModelLow physical activityOsteoporosis Knowledge TestPhysical Activity QuestionnaireMultivariate logistic regressionMulti-center trialCross-sectional studyHealth Belief ScalePreventive health behaviorsChinese individualsManual labor occupationD intakeCalcium intakeAverage BMIOsteoporosis knowledgeIncreased bone resorption during tenofovir plus lopinavir/ritonavir therapy in Chinese individuals with HIV
Hsieh E, Fraenkel L, Xia W, Hu YY, Han Y, Insogna K, Yin MT, Xie J, Zhu T, Li T. Increased bone resorption during tenofovir plus lopinavir/ritonavir therapy in Chinese individuals with HIV. Osteoporosis International 2014, 26: 1035-1044. PMID: 25224293, PMCID: PMC4334679, DOI: 10.1007/s00198-014-2874-3.Peer-Reviewed Original ResearchConceptsHuman immunodeficiency virusLopinavir/ritonavirBone turnover markersBone resorption marker levelsResorption marker levelsNon-Chinese populationsAntiretroviral therapyTreatment failureImmunodeficiency virusMarker levelsSkeletal metabolismC-terminal cross-linking telopeptideLopinavir/ritonavir therapyTreatment-naïve patientsFirst-line therapyBone resorption markersProcollagen type 1Multi-center trialPlasma samplesChinese individualsN-terminal propeptideType 1 collagenRitonavir therapyTurnover markersResorption markers
2013
Needs and Priorities in Women's Health Training: Perspectives from an Internal Medicine Residency Program
Hsieh E, Nunez-Smith M, Henrich JB. Needs and Priorities in Women's Health Training: Perspectives from an Internal Medicine Residency Program. Journal Of Women's Health 2013, 22: 667-672. PMID: 23915106, PMCID: PMC4047848, DOI: 10.1089/jwh.2013.4264.Peer-Reviewed Original Research
2006
Sexually transmitted infections and private physicians in Peru, 2003
Hsieh EJ, Blas MM, La Rosa Roca S, Garcia PJ. Sexually transmitted infections and private physicians in Peru, 2003. BULL PAN AM HEALTH ORGAN 2006, 20: 223-229. PMID: 17316480, DOI: 10.1590/s1020-49892006000900002.Peer-Reviewed Original ResearchConceptsPrivate physiciansPrivate practiceCases of STIsPublic health problemInterventional trialsFemale patientsNumber of physiciansPhysician managementSTI casesHealth problemsMedical careDoor surveyPhysician densityMedical officesPhysiciansCities of PeruDemographic informationSTIsPatientsClinical positionsInfectionPhysician workforceMonthsConsultationPublic practice