2020
TRiC/CCT Complex, a Binding Partner of NS1 Protein, Supports the Replication of Zika Virus in Both Mammalians and Mosquitoes
Wang Y, Uraki R, Hwang J, Fikrig E. TRiC/CCT Complex, a Binding Partner of NS1 Protein, Supports the Replication of Zika Virus in Both Mammalians and Mosquitoes. Viruses 2020, 12: 519. PMID: 32397176, PMCID: PMC7290343, DOI: 10.3390/v12050519.Peer-Reviewed Original ResearchConceptsZika virusZIKV replicationZIKV NS1 proteinGuillain-Barré syndromeNS1 proteinTRiC/CCT complexPromising therapeutic targetZIKV infectionCongenital microcephalySpecific treatmentTherapeutic targetHost factorsVirusMosquitoesSyndromeVaccineSymptomsInfectionMicrocephalyProteinReplicationImportant role
2003
Immunoassay Targeting Nonstructural Protein 5 To Differentiate West Nile Virus Infection from Dengue and St. Louis Encephalitis Virus Infections and from Flavivirus Vaccination
Wong SJ, Boyle RH, Demarest VL, Woodmansee AN, Kramer LD, Li H, Drebot M, Koski RA, Fikrig E, Martin DA, Shi PY. Immunoassay Targeting Nonstructural Protein 5 To Differentiate West Nile Virus Infection from Dengue and St. Louis Encephalitis Virus Infections and from Flavivirus Vaccination. Journal Of Clinical Microbiology 2003, 41: 4217-4223. PMID: 12958248, PMCID: PMC193845, DOI: 10.1128/jcm.41.9.4217-4223.2003.Peer-Reviewed Original ResearchConceptsSt. Louis encephalitis virus infectionEncephalitis virus infectionWest Nile virusWNV infectionVirus infectionFlavivirus vaccinationWest Nile virus infectionNatural WNV infectionWNV structural proteinsDetection of antibodiesBlood transfusionRecent infectionOrgan transplantationSerologic assaysImmune responseDengue virusInfectionProtein 3Nonstructural protein 3Nile virusNatural transmissionProtein 5Structural proteinsLack specificityFrequent epidemics