2023
Restrictive Versus Liberal Red Blood Cell Transfusion Strategies for Patients with Hematologic Malignancies Receiving Intensive Chemotherapy
Radford M, Watson M, Sirotich E, Pitre T, Britto J, Brunskill S, Fergusson D, Arnold D, Estcourt L. Restrictive Versus Liberal Red Blood Cell Transfusion Strategies for Patients with Hematologic Malignancies Receiving Intensive Chemotherapy. Blood 2023, 142: 5573. DOI: 10.1182/blood-2023-180430.Peer-Reviewed Original ResearchRed blood cell transfusion strategyHematopoietic stem cell transplantationLiberal transfusion strategyRestrictive transfusion strategyTransfusion strategyRed blood cellsCertainty of evidenceIntensive chemotherapyHematologic malignanciesRisk ratioRed blood cell transfusionConfidence intervalsMean differenceRed blood cell unitsRed blood cell usageClinically significant bleedingCochrane's standard methodological proceduresStem cell transplantationMalignant hematological disordersCochrane Central Register of Controlled TrialsCentral Register of Controlled TrialsLow hemoglobin levelRegister of Controlled TrialsReview's primary outcomesCochrane Central RegisterImpact of iron supplementation on patient outcomes for women with abnormal uterine bleeding: a protocol for a systematic review and meta-analysis
Nazaryan H, Watson M, Ellingham D, Thakar S, Wang A, Pai M, Liu Y, Rochwerg B, Gabarin N, Arnold D, Sirotich E, Zeller M. Impact of iron supplementation on patient outcomes for women with abnormal uterine bleeding: a protocol for a systematic review and meta-analysis. Systematic Reviews 2023, 12: 121. PMID: 37443063, PMCID: PMC10347734, DOI: 10.1186/s13643-023-02222-4.Peer-Reviewed Original ResearchConceptsIron deficiency anemiaQuality of lifeHeavy menstrual bleedingStandard of carePatient outcomesIron interventionsSystematic reviewUterine bleedingCombination therapyIron supplementationIron indicesRed blood cell transfusionIron deficiencyRed blood cell utilizationAbnormal uterine bleedingIntraoperative blood lossBlood cell transfusionEvidence-based clinical practiceMeta-analyzed outcomesSystematic literature searchCost of treatmentWeb of ScienceCell transfusionHospital stayAdverse events
2021
Perioperative Anemia Management in Women Undergoing Gynecologic Procedures: A 10 Year Multisite Study
Gabarin N, Sirotich E, Liu Y, Pai M, Luketic L, Arnold D, Zeller M. Perioperative Anemia Management in Women Undergoing Gynecologic Procedures: A 10 Year Multisite Study. Blood 2021, 138: 752. DOI: 10.1182/blood-2021-154182.Peer-Reviewed Original ResearchPreoperative anemiaRetrospective cohort studyDay of surgeryGynecologic surgeryPerioperative periodHospital admissionICU admissionTransfusion rateMalignancy groupPreoperative HbCohort studyAdverse outcomesRBC utilizationAcademic hospitalMalignancy diagnosisGynecologic proceduresUnits RBCIntensive care unit admissionPatient blood management initiativesRed blood cell transfusionIron useGynecologic surgery patientsIntravenous iron useNon-malignancy groupNon-malignancy patients
2019
Impact of Iron Supplementation on Patient Outcomes in Women Undergoing Gynecological Procedures: Systematic Review and Meta-Analysis of Randomized Trials
Sirotich E, Jamula E, Wang A, Arnold D, Zeller M. Impact of Iron Supplementation on Patient Outcomes in Women Undergoing Gynecological Procedures: Systematic Review and Meta-Analysis of Randomized Trials. Blood 2019, 134: 59. DOI: 10.1182/blood-2019-122269.Peer-Reviewed Original ResearchPerioperative RBC transfusionPreoperative Hb levelErythropoietin-stimulating agentsRBC transfusion ratesAdverse eventsIron supplementationGynecological proceduresRBC transfusionPatient outcomesHb levelsSystematic reviewPostoperative HbTransfusion rateHemoglobin levelsIron supplementsPerioperative red blood cell transfusionIncidence of AEsOccurrence of AEsRed blood cell transfusionNumber of AEsPatient blood management strategiesPostoperative Hb levelsPreoperative iron supplementationBlood cell transfusionRisk of anemia