2023
Characteristics associated with poor COVID-19 outcomes in people with psoriasis, psoriatic arthritis and axial spondyloarthritis: data from the COVID-19 PsoProtect and Global Rheumatology Alliance physician-reported registries
Machado P, Schäfer M, Mahil S, Liew J, Gossec L, Dand N, Pfeil A, Strangfeld A, Regierer A, Fautrel B, Alonso C, Saad C, Griffiths C, Lomater C, Miceli-Richard C, Wendling D, Rodriguez D, Wiek D, Mateus E, Sirotich E, Soriano E, Ribeiro F, Omura F, Martins F, Santos H, Dau J, Barker J, Hausmann J, Hyrich K, Gensler L, Silva L, Jacobsohn L, Carmona L, Pinheiro M, Zelaya M, de los Ángeles Severina M, Yates M, Dubreuil M, Gore-Massy M, Romeo N, Haroon N, Sufka P, Grainger R, Hasseli R, Lawson-Tovey S, Bhana S, Pham T, Olofsson T, Bautista-Molano W, Wallace Z, Yiu Z, Yazdany J, Robinson P, Smith C. Characteristics associated with poor COVID-19 outcomes in people with psoriasis, psoriatic arthritis and axial spondyloarthritis: data from the COVID-19 PsoProtect and Global Rheumatology Alliance physician-reported registries. Annals Of The Rheumatic Diseases 2023, 82: 698-709. PMID: 36787993, PMCID: PMC10176347, DOI: 10.1136/ard-2022-223499.Peer-Reviewed Original ResearchConceptsSevere COVID-19High disease activityPandemic time periodDisease activityPsoriatic arthritisMale sexAxial spondyloarthritisCOVID-19Multivariable ordinal logistic regressionPoor COVID-19 outcomesOlder ageFuture respiratory pandemicsCOVID-19 severityCOVID-19 outcomesComorbidity burdenGlucocorticoid intakeGlucocorticoid useCancer comorbidityClinical characteristicsCOVID-19 waveRisk stratificationOrdinal logistic regressionReduced oddsSeverity ScaleRespiratory pandemic
2022
Factors associated with severe COVID-19 in people with idiopathic inflammatory myopathy: results from the COVID-19 Global Rheumatology Alliance physician-reported registry
Yeoh S, Gianfrancesco M, Lawson-Tovey S, Hyrich K, Strangfeld A, Gossec L, Carmona L, Mateus E, Schäfer M, Richez C, Hachulla E, Holmqvist M, Scirè C, Lorenz H, Voll R, Hasseli R, Jayatilleke A, Hsu T, D’Silva K, Pimentel-Quiroz V, del Mercado M, Shinjo S, dos Reis Neto E, da Rocha L, de Oliveira e Silva Montandon A, Pons-Estel G, Ornella S, Exeni M, Velozo E, Jordan P, Sirotich E, Hausmann J, Liew J, Jacobsohn L, Gore-Massy M, Sufka P, Grainger R, Bhana S, Wallace Z, Robinson P, Yazdany J, Machado P. Factors associated with severe COVID-19 in people with idiopathic inflammatory myopathy: results from the COVID-19 Global Rheumatology Alliance physician-reported registry. RMD Open 2022, 8: e002508. PMID: 36100295, PMCID: PMC9471207, DOI: 10.1136/rmdopen-2022-002508.Peer-Reviewed Original ResearchConceptsIdiopathic inflammatory myopathiesSevere COVID-19Prednisolone-equivalent doseHigh disease activityDisease activityInflammatory myopathiesMale sexSevere outcomesCOVID-19Multivariable ordinal logistic regressionOlder ageHigher comorbidity burdenLarge registry dataCOVID-19 diagnosisComorbidity burdenRituximab exposureClinical characteristicsRisk stratificationOrdinal logistic regressionRegistry dataHospitalisationSeverity ScaleDemographic dataLogistic regressionPatientsOP0249 CHARACTERISTICS ASSOCIATED WITH POOR COVID-19 OUTCOMES IN PEOPLE WITH PSORIASIS AND SPONDYLOARTHRITIS: DATA FROM THE COVID-19 PsoProtect AND GLOBAL RHEUMATOLOGY ALLIANCE PHYSICIAN-REPORTED REGISTRIES
Machado P, Schaefer M, Mahil S, Dand N, Gianfrancesco M, Lawson-Tovey S, Yiu Z, Yates M, Hyrich K, Gossec L, Carmona L, Mateus E, Wiek D, Bhana S, Gore-Massy M, Grainger R, Hausmann J, Sufka P, Sirotich E, Wallace Z, Olofsson T, Lomater C, Romeo N, Wendling D, Pham T, Miceli Richard C, Fautrel B, Silva L, Santos H, Martins F, Hasseli R, Pfeil A, Regierer A, Isnardi C, Soriano E, Quintana R, Omura F, Machado Ribeiro F, Pinheiro M, Bautista-Molano W, Alpizar-Rodriguez D, Saad C, Dubreuil M, Haroon N, Gensler L, Dau J, Jacobsohn L, Liew J, Strangfeld A, Barker J, Griffiths C, Robinson P, Yazdany J, Smith C. OP0249 CHARACTERISTICS ASSOCIATED WITH POOR COVID-19 OUTCOMES IN PEOPLE WITH PSORIASIS AND SPONDYLOARTHRITIS: DATA FROM THE COVID-19 PsoProtect AND GLOBAL RHEUMATOLOGY ALLIANCE PHYSICIAN-REPORTED REGISTRIES. Annals Of The Rheumatic Diseases 2022, 81: 163-164. DOI: 10.1136/annrheumdis-2022-eular.1753.Peer-Reviewed Original ResearchIL-23/IL-12High disease activitySevere COVID-19 outcomesDisease activityAssociated with severe COVID-19 outcomesCOVID-19 outcomesGlobal Rheumatology AllianceMale sexPooled analysis of dataFactors associated with severe COVID-19 outcomesDiagnosis of PsOPsoriasis patient registriesIL-17 inhibitorsAnti-rheumatic drugsOlder agePhysician-reported disease activityChronic kidney diseaseMultivariate ordinal logistic regression modelGC intakeIL-17iCOVID-19 severityActive diseaseSpecificity of patientsCOVID-19 Global Rheumatology AllianceAxial spondyloarthritisCharacteristics associated with poor COVID-19 outcomes in individuals with systemic lupus erythematosus: data from the COVID-19 Global Rheumatology Alliance
Ugarte-Gil M, Alarcón G, Izadi Z, Duarte-García A, Reátegui-Sokolova C, Clarke A, Wise L, Pons-Estel G, Santos M, Bernatsky S, Ribeiro S, Al Emadi S, Sparks J, Hsu T, Patel N, Gilbert E, Valenzuela-Almada M, Jönsen A, Landolfi G, Fredi M, Goulenok T, Devaux M, Mariette X, Queyrel V, Romão V, Sequeira G, Hasseli R, Hoyer B, Voll R, Specker C, Baez R, Castro-Coello V, Ficco H, Neto E, Ferreira G, Monticielo O, Sirotich E, Liew J, Hausmann J, Sufka P, Grainger R, Bhana S, Costello W, Wallace Z, Jacobsohn L, Taylor T, Ja C, Strangfeld A, Mateus E, Hyrich K, Carmona L, Lawson-Tovey S, Kearsley-Fleet L, Schäfer M, Machado P, Robinson P, Gianfrancesco M, Yazdany J. Characteristics associated with poor COVID-19 outcomes in individuals with systemic lupus erythematosus: data from the COVID-19 Global Rheumatology Alliance. Annals Of The Rheumatic Diseases 2022, 81: 970-978. PMID: 35172961, PMCID: PMC8882632, DOI: 10.1136/annrheumdis-2021-221636.Peer-Reviewed Original ResearchConceptsSystemic lupus erythematosusCOVID-19 outcomesSevere outcomesDisease activityLupus erythematosusHigher SLE disease activityActive systemic lupus erythematosusMultivariable ordinal logistic regression modelsSevere COVID-19 outcomesPoor COVID-19 outcomesSLE disease activitySex-adjusted modelsMore severe outcomesCOVID-19 severityCOVID-19Logistic regression modelsOrdinal logistic regression modelsPrednisone doseMale sexGlobal RegistryWorse outcomesMultivariable modelCurrent treatmentComorbiditiesOlder age
2021
OP0286 CHARACTERISTICS ASSOCIATED WITH SEVERE COVID-19 OUTCOMES IN SYSTEMIC LUPUS ERYTHEMATOSUS (SLE): RESULTS FROM THE COVID-19 GLOBAL RHEUMATOLOGY ALLIANCE (COVID-19 GRA)
Ugarte-Gil M, Alarcon G, Seet A, Izadi Z, Reategui Sokolova C, Clarke A, Wise L, Pons-Estel G, Santos M, Bernatsky S, Mathias L, Lim N, Sparks J, Wallace Z, Hyrich K, Strangfeld A, Gossec L, Carmona L, Mateus E, Lawson-Tovey S, Trupin L, Rush S, Schmajuk G, Katz P, Jacobsohn L, Al Emadi S, Gilbert E, Duarte-Garcia A, Valenzuela-Almada M, Hsu T, D’silva K, Serling-Boyd N, Dieudé P, Nikiphorou E, Kronzer V, Singh N, Wallace B, Akpabio A, Thomas R, Bhana S, Costello W, Grainger R, Hausmann J, Liew J, Sirotich E, Sufka P, Robinson P, Machado P, Gianfrancesco M, Yazdany J. OP0286 CHARACTERISTICS ASSOCIATED WITH SEVERE COVID-19 OUTCOMES IN SYSTEMIC LUPUS ERYTHEMATOSUS (SLE): RESULTS FROM THE COVID-19 GLOBAL RHEUMATOLOGY ALLIANCE (COVID-19 GRA). Annals Of The Rheumatic Diseases 2021, 80: 173.2-175. DOI: 10.1136/annrheumdis-2021-eular.2984.Peer-Reviewed Original ResearchSystemic lupus erythematosusChronic renal diseaseModerate/high disease activityNon-invasive ventilationSevere COVID-19 outcomesBristol-Myers SquibbDisease activityGrant/research supportRenal diseaseCOVID-19 outcomesCOVID-19 diagnosisDrug monotherapyImmunomodulatory therapyGlobal Rheumatology AllianceMembrane oxygenationCOVID-19 Global Rheumatology AllianceNational Institute for Health ResearchMale sexModerate to high daily dosesSLE adult patientsBristol-MyersSystemic lupus erythematosus patientsSystemic lupus erythematosus therapyCardiovascular diseaseOdds of poor outcomeFactors associated with COVID-19-related death in people with rheumatic diseases: results from the COVID-19 Global Rheumatology Alliance physician-reported registry
Strangfeld A, Schäfer M, Gianfrancesco M, Lawson-Tovey S, Liew J, Ljung L, Mateus E, Richez C, Santos M, Schmajuk G, Scirè C, Sirotich E, Sparks J, Sufka P, Thomas T, Trupin L, Wallace Z, Al-Adely S, Bachiller-Corral J, Bhana S, Cacoub P, Carmona L, Costello R, Costello W, Gossec L, Grainger R, Hachulla E, Hasseli R, Hausmann J, Hyrich K, Izadi Z, Jacobsohn L, Katz P, Kearsley-Fleet L, Robinson P, Yazdany J, Machado P, Dahou B, Pinheiro M, Ribeiro F, Chassin-Trubert A, Ibáñez S, Dong L, Cajas L, Hamoud H, Avouac J, Belin V, Borie R, Chazerain P, Chevalier X, Claudepierre P, Clavel G, Colette-Cedoz M, Combe B, Constant E, Costedoat-Chalumeau N, Desmurs M, Devauchelle-Pensec V, Devaux M, Dhote R, Dieudonné Y, Domont F, Duret P, Ebbo M, Ebstein E, Mahou S, Fautrel B, Felten R, Flipo R, Foltz V, Froissart A, Galland J, Gaud-Listrat V, Georgin-Lavialle S, Giraud-Morelet A, Quitrec J, Goupille P, Govindaraju-Audouard S, Grados F, Guillaume-Czitrom S, Hermet M, Hittinger-Roux A, Hudry C, Kone-Paut I, La Batide Alanore S, Lafforgue P, Lahalle S, Lambrecht I, Langlois V, Larbre J, Ledoult E, Leroux C, Liote F, Maria A, Marotte H, Mekinian A, Melki I, Messer L, Michel C, Morel G, Morel J, Paris-Havard M, Pertuiset E, Pham T, Renard M, Revuz S, Rivière S, Rousselin C, Roux C, Rouzaud D, Sellam J, Seror R, Servettaz A, Sobanski V, Sordet C, Spielmann L, Tieulié N, Tison A, Trijau S, Virone A, Warzocha U, Wendling D, Albach F, Aries P, Decker E, Hartmann U, Henes J, Hoyer B, Krause A, Krüger K, Lorenz H, Müller-Ladner U, Pfeil A, Regierer A, Richter J, Rihl M, Schmeiser T, Schulze-Koops H, Specker C, Voll R, Werner S, Melgar G, Vojdanian, Andreoli L, Bartoloni-Bocci E, Benucci M, Campanaro F, Caprioli M, Carboni D, Carrara G, Cipolletta E, Crotti C, Dallagiacoma G, Faggioli P, Foti R, Franceschini F, Fredi M, Guidelli G, Iannone F, Landolfi G, Lomater C, Nalli C, Parisi S, Quartuccio L, Raffeiner B, Reggia R, Riva M, Romeo N, Rotondo C, Silvagni E, Sinigaglia L, Tinazzi I, Zanetti A, Zanframundo G, Abutiban F, Alpízar-Rodríguez D, Rull-Gabayet M, Irazoque F, Jimenez X, Martín-Nares E, Castillo-Ortiz A, Rodriguez-Reyna T, Rosete D, Zamora-Tehozol E, Vega-Morales D, Zaueta-Montiel B, Al-Adhoubi N, Salim B, Giraldo E, Salinas A, Ugarte-Gil M, Almeida D, Bernardes M, Machado R, Rato M, Al-Emadi S, Conway R, Flood R, Alegre-Sancho J, Coro M, de la Torre-Rubio N, Esteban J, del Martin M, Puerta J, Back J, Dastmalchi M, Dupré B, Grenholm E, Hensvold A, Knight A, Akar S, Icacan O, Chadwick L, Devine K, Dunt S, Fusi L, Jones C, Macphie E, Nikiphorou E, O'Kane D, O'Reilly S, Patel S, Salerno R, Thornton L, Tyler J, Vandevelde C, Warner E, Yeoh S, Baig S, Bajwa H, Ban B, Berglund V, Calabrese C, D'Silva K, Dahle A, Dao K, Daver N, Davis W, Dorman W, Fatemeh E, Fields T, Hargrove J, Harvey M, Hilton M, Hsu T, Izadi Z, Jayatilleke A, Karp D, Kepecs G, Kramer N, Lamore C, Lebedoff N, Leonard S, Mody S, Morgan J, Pfeifer E, Quiceno G, Quinet R, Rosenstein E, Ruderman E, Scopelitis E, Serling-Boyd N, Siddique F, Skemp A, Sparks J, Todd D, Toribio K, Wallwork R, Webb-Detiege T, White D, Wilson J, Winter M, Wise L, Wolff A, Young K, Zakem J, Zell J, Zimmerman K. Factors associated with COVID-19-related death in people with rheumatic diseases: results from the COVID-19 Global Rheumatology Alliance physician-reported registry. Annals Of The Rheumatic Diseases 2021, 80: 930-942. PMID: 33504483, PMCID: PMC7843211, DOI: 10.1136/annrheumdis-2020-219498.Peer-Reviewed Original ResearchConceptsDisease-modifying anti-rheumatic drugsCOVID-19-related deathsHigh disease activityRheumatic diseasesDisease activityHigher oddsBiological disease-modifying anti-rheumatic drugsMultivariable logistic regression modelRegistry of adultsRheumatic disease diagnosisAnti-rheumatic drugsChronic lung diseaseDisease-specific factorsAdequate disease controlLogistic regression modelsGlucocorticoid dosageMethotrexate monotherapyPrimary outcomeSmoking statusMale sexLung diseaseCardiovascular diseaseIndependent factorsDisease categoriesDisease control
2020
Management of major bleeds in patients with immune thrombocytopenia
Mithoowani S, Cervi A, Shah N, Ejaz R, Sirotich E, Barty R, Li N, Nazy I, Arnold D. Management of major bleeds in patients with immune thrombocytopenia. Journal Of Thrombosis And Haemostasis 2020, 18: 1783-1790. PMID: 32219982, DOI: 10.1111/jth.14809.Peer-Reviewed Original ResearchConceptsMajor bleedsImmune thrombocytopeniaEmergency departmentITP patientsEvidence-based treatment strategiesIntravenous immune globulinRetrospective cohort studyPermanent neurological disabilityITP therapyMajor bleedingRecurrent bleedsHemodynamic instabilityMinor bleedingCohort studyED visitsGross hematuriaImmune globulinAcute treatmentNeurological disabilityArterial thrombosisPlatelet transfusionsSevere thrombocytopeniaSignificant morbidityMale sexRisk factors